Histopathological and biochemical changes in the liver, kidney, and bloodof amphibians intoxicated with cadmium

Marcela Fatima MEDINA, (Institute of Biology, Faculty of Biochemistry, Chemistry, and Pharmacy, National University of Tucumán,San Miguel de Tucumán, Argentina)
Maria Elena GONZALEZ, (Institute of Biology, Faculty of Biochemistry, Chemistry, and Pharmacy, National University of Tucumán,San Miguel de Tucumán, Argentina)
Sandra Maria Roxana KLYVER, (Faculty of Medicine, National University of Tucumán, San Miguel de Tucumán, Argentina)
Iris Maria AYBAR ODSTRCIL (Faculty of Medicine, National University of Tucumán, San Miguel de Tucumán, Argentina)
Turkish Journal of Biology
2 0
Yıl: 2016 Cilt: 40 Sayı: 1 Sayfa Aralığı: 229 - 238 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Histopathological and biochemical changes in the liver, kidney, and bloodof amphibians intoxicated with cadmium

Öz:
The worldwide decline in amphibian populations has made heavy metal pollution a subject of interest. The aim of this work was to analyze the effect of sublethal doses of cadmium (Cd) on the liver, kidney, and blood of Rhinella arenarum specimens. Serum markers indicative of hepatic injury (gamma glutamyltransferase, alkaline phosphatase, pseudo cholinesterase, and total cholesterol) and markers of renal dysfunction (blood urea nitrogen, serum creatinine, calcium, and glucose) showed variation in animals treated with a 0.5 mg/kg dose compared to controls. Histopathological images revealed alterations in the liver (hepatocyte ballooning and hyperplasia of Kupffer cells) and kidney (renal tubular lumen dilation with tubular necrosis) of animals with abnormal serum markers. The above-mentioned lesions were more evident with the 5 mg/kg dose. With the 0.5 mg/kg dose, hematological values remained normal with the exception of the leukocyte formula. Animals treated with 5 mg/kg showed a significant decrease in both white and red blood cell counts and hematocrit and hemoglobin values. Differential leukocyte counts showed neutrophilia, monocytosis, and lymphopenia. Morphological aberrations were found in white and red blood cells. Results indicated that the evaluation of morphological and functional parameters in kidney, liver, and blood is required in order to monitor amphibian populations exposed to chemical contaminants.
Anahtar Kelime:

Konular: Biyoloji
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA MEDINA M, GONZALEZ M, KLYVER S, AYBAR ODSTRCIL I (2016). Histopathological and biochemical changes in the liver, kidney, and bloodof amphibians intoxicated with cadmium. , 229 - 238.
Chicago MEDINA Marcela Fatima,GONZALEZ Maria Elena,KLYVER Sandra Maria Roxana,AYBAR ODSTRCIL Iris Maria Histopathological and biochemical changes in the liver, kidney, and bloodof amphibians intoxicated with cadmium. (2016): 229 - 238.
MLA MEDINA Marcela Fatima,GONZALEZ Maria Elena,KLYVER Sandra Maria Roxana,AYBAR ODSTRCIL Iris Maria Histopathological and biochemical changes in the liver, kidney, and bloodof amphibians intoxicated with cadmium. , 2016, ss.229 - 238.
AMA MEDINA M,GONZALEZ M,KLYVER S,AYBAR ODSTRCIL I Histopathological and biochemical changes in the liver, kidney, and bloodof amphibians intoxicated with cadmium. . 2016; 229 - 238.
Vancouver MEDINA M,GONZALEZ M,KLYVER S,AYBAR ODSTRCIL I Histopathological and biochemical changes in the liver, kidney, and bloodof amphibians intoxicated with cadmium. . 2016; 229 - 238.
IEEE MEDINA M,GONZALEZ M,KLYVER S,AYBAR ODSTRCIL I "Histopathological and biochemical changes in the liver, kidney, and bloodof amphibians intoxicated with cadmium." , ss.229 - 238, 2016.
ISNAD MEDINA, Marcela Fatima vd. "Histopathological and biochemical changes in the liver, kidney, and bloodof amphibians intoxicated with cadmium". (2016), 229-238.
APA MEDINA M, GONZALEZ M, KLYVER S, AYBAR ODSTRCIL I (2016). Histopathological and biochemical changes in the liver, kidney, and bloodof amphibians intoxicated with cadmium. Turkish Journal of Biology, 40(1), 229 - 238.
Chicago MEDINA Marcela Fatima,GONZALEZ Maria Elena,KLYVER Sandra Maria Roxana,AYBAR ODSTRCIL Iris Maria Histopathological and biochemical changes in the liver, kidney, and bloodof amphibians intoxicated with cadmium. Turkish Journal of Biology 40, no.1 (2016): 229 - 238.
MLA MEDINA Marcela Fatima,GONZALEZ Maria Elena,KLYVER Sandra Maria Roxana,AYBAR ODSTRCIL Iris Maria Histopathological and biochemical changes in the liver, kidney, and bloodof amphibians intoxicated with cadmium. Turkish Journal of Biology, vol.40, no.1, 2016, ss.229 - 238.
AMA MEDINA M,GONZALEZ M,KLYVER S,AYBAR ODSTRCIL I Histopathological and biochemical changes in the liver, kidney, and bloodof amphibians intoxicated with cadmium. Turkish Journal of Biology. 2016; 40(1): 229 - 238.
Vancouver MEDINA M,GONZALEZ M,KLYVER S,AYBAR ODSTRCIL I Histopathological and biochemical changes in the liver, kidney, and bloodof amphibians intoxicated with cadmium. Turkish Journal of Biology. 2016; 40(1): 229 - 238.
IEEE MEDINA M,GONZALEZ M,KLYVER S,AYBAR ODSTRCIL I "Histopathological and biochemical changes in the liver, kidney, and bloodof amphibians intoxicated with cadmium." Turkish Journal of Biology, 40, ss.229 - 238, 2016.
ISNAD MEDINA, Marcela Fatima vd. "Histopathological and biochemical changes in the liver, kidney, and bloodof amphibians intoxicated with cadmium". Turkish Journal of Biology 40/1 (2016), 229-238.
Sayfa Oluşturulma Tarihi
23-04-2024 0:40

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