Yıl: 2016 Cilt: 22 Sayı: 3 Sayfa Aralığı: 69 - 73 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Immunosuppressive Therapy and Hepatitis B Virus Reactivation

Öz:
Hepatit B virüs (HBV) reaktivasyonu, inaktif hepatit B yüzey antijeni taşıyıcılarında veya iyileşmiş HBV enfeksiyonu olan kişilerde aktif nekroenflamatuvar karaciğer hastalığının yeniden ortaya çıkmasıdır. Malign, otoimmün ve romatizmal hastalıklarda kullanılan immünsupresif tedaviler, HBV immün baskılanmasının kaybına bağlı olarak HBV reaktivasyonu ve alevlenme için risk oluştururlar. HBV reaktivasyonu antiviral profilaksi ile önlenebilir. İmmünsüpresif tedaviye başlandıktan sonra verilen antiviral ilaçlar karaciğer hasarını önlemek için daha az etkili olup tercih edilmemelidir
Anahtar Kelime:

Konular: Gastroenteroloji ve Hepatoloji

İmmünsüpresif Tedavi ve Hepatit B Virüs Reaktivasyonu

Öz:
Reactivation of hepatitis B virus (HBV) refers to reappearance of active necroinflammatory disease of the liver in an individual at an inactive hepatitis B surface antigen carrier state or who is known to have resolved HBV infection. Patients receiving immunosuppressive therapy for malignant, autoimmune or chronic rheumatic diseases are at risk for HBV reactivation and a flare of their HBV infection due to loss of HBV immune control. HBV reactivation can be prevented by antiviral prophylaxis. Antiviral drugs given after the initiation of immunosuppressive therapy are less effective for liver injury and should not be preferred.
Anahtar Kelime:

Konular: Gastroenteroloji ve Hepatoloji
Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık
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APA Koksal I (2016). Immunosuppressive Therapy and Hepatitis B Virus Reactivation. , 69 - 73.
Chicago Koksal Iftihar Immunosuppressive Therapy and Hepatitis B Virus Reactivation. (2016): 69 - 73.
MLA Koksal Iftihar Immunosuppressive Therapy and Hepatitis B Virus Reactivation. , 2016, ss.69 - 73.
AMA Koksal I Immunosuppressive Therapy and Hepatitis B Virus Reactivation. . 2016; 69 - 73.
Vancouver Koksal I Immunosuppressive Therapy and Hepatitis B Virus Reactivation. . 2016; 69 - 73.
IEEE Koksal I "Immunosuppressive Therapy and Hepatitis B Virus Reactivation." , ss.69 - 73, 2016.
ISNAD Koksal, Iftihar. "Immunosuppressive Therapy and Hepatitis B Virus Reactivation". (2016), 69-73.
APA Koksal I (2016). Immunosuppressive Therapy and Hepatitis B Virus Reactivation. Viral Hepatitis Journal, 22(3), 69 - 73.
Chicago Koksal Iftihar Immunosuppressive Therapy and Hepatitis B Virus Reactivation. Viral Hepatitis Journal 22, no.3 (2016): 69 - 73.
MLA Koksal Iftihar Immunosuppressive Therapy and Hepatitis B Virus Reactivation. Viral Hepatitis Journal, vol.22, no.3, 2016, ss.69 - 73.
AMA Koksal I Immunosuppressive Therapy and Hepatitis B Virus Reactivation. Viral Hepatitis Journal. 2016; 22(3): 69 - 73.
Vancouver Koksal I Immunosuppressive Therapy and Hepatitis B Virus Reactivation. Viral Hepatitis Journal. 2016; 22(3): 69 - 73.
IEEE Koksal I "Immunosuppressive Therapy and Hepatitis B Virus Reactivation." Viral Hepatitis Journal, 22, ss.69 - 73, 2016.
ISNAD Koksal, Iftihar. "Immunosuppressive Therapy and Hepatitis B Virus Reactivation". Viral Hepatitis Journal 22/3 (2016), 69-73.