Investigation of Acute Phase Reactants and Antioxidant Capacity in Calves Infected with Cryptosporidium parvum
Yıl: 2017 Cilt: 23 Sayı: 3 Sayfa Aralığı: 481 - 485 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022
Investigation of Acute Phase Reactants and Antioxidant Capacity in Calves Infected with Cryptosporidium parvum
Öz: Kriptosporidiozis, fekal-oral yolla bulaşan bir zoonoz enfeksiyondur. Cryptosporidium parvum yaygın prevalans göstermekle birlikte, buzağılarda daha epidemik olarak seyretmektedir. Hastalık yüksek morbidite ve mortalitesine bağlı olarak, ciddi ekonomik kayıplara neden olur. Bu çalışmada, C. parvum ile enfekte buzağılara halofuginon (100 µg /kg/gün-7 gün) tedavisi uygulanmış ve bu tedavinin akut faz proteinleri ile antioksidant kapasite üzerindeki etkileri araştırılmıştır. Çalışma grubu, C. parvum ile enfekte, 1-3 haftalık 10 Holstein buzağıdan oluşturulmuştur. Tedavi öncesi ve sonrası alınan kan numunelerinde, serum amiloid A (SAA), haptoglobulin (Hp), C-reaktif protein (CRP), seruloplazmin (CP), malondialdehid (MDA) seviyeleri ile süperoksid dismutaz (SOD) ve adenozin deaminaz (ADA) aktiviteleri tespit edilmiştir. Elde edilen veriler, tedavi öncesi ve sonrası SAA, CRP ve MDA seviyelerinde istatistiksel bir farklılık olmadığını, fakat tedavi sonrası Hp (P<0.001) ve CP (P<0.05) seviyeleri ile ADA (P<0.05) ve SOD (P<0.001) aktivitelerinde istatistiksel olarak anlamlı bir düşüş meydana geldiğini ortaya koymuştur. Sonuç olarak, C. parvum ile enfekte buzağılarda tedavi ile ADA ve SOD aktiviteleri ile Hp ve CP seviyelerinde düşüş sağlandığı tespit edilmiştir
Anahtar Kelime: Konular:
Cryptosporidium parvum ile Enfekte Buzağılarda Akut Faz Reaktanları ve Antioksidant Kapasitenin Araştırılması
Öz: Cryptosporidiosis is a zoonotic infection contaminating via fecal-oral route. Cryptosporidium parvum has a wide host prevalance, but is more epidemic in calves. This disease courses with high morbidity and mortality resulting considerable economic losses. In this study, halofuginon (100 µg /kg/day for 7 days) was applied to calves infected with C. parvum and the effect of this treatment on acute phase proteins and antioxidant capacity were investigated. Study group was comprised of sera of 10 Holstein calves aged 1-3 weeks, infected with C. parvum. Blood samples were obtained from the animals before and after treatment of 7 days and serum amyloid A (SAA), haptoglobin (Hp), C-reactive protein (CRP), ceruloplasmin (CP), malondialdehyde (MDA) levels and superoxide dismutase (SOD) and adenosine deaminase (ADA) activities were measured in sera. Obtained data showed that there was no statistical difference between pre and post treatment SAA, CRP and MDA levels, but a decrease was determined in post treatment Hp (P<0.001) and CP (P<0.05) levels, with ADA (P<0.05) and SOD (P<0.001) activities. Eventually, it was determined that ADA and SOD activities and Hp and CP levels decreases by treatment in calves infected with C. parvum
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | ÇENESİZ M, sagkan ozturk a, DALĞIN D, Yarim G, ÇİFTCİ G, ÖZDEMİR R, GÜZEL M, Kazak F, ÇENESİZ S (2017). Investigation of Acute Phase Reactants and Antioxidant Capacity in Calves Infected with Cryptosporidium parvum. , 481 - 485. |
| Chicago | ÇENESİZ METİN,sagkan ozturk aliye,DALĞIN Duygu,Yarim Gul Fatma,ÇİFTCİ GÜLAY,ÖZDEMİR Ramazan,GÜZEL Murat,Kazak Filiz,ÇENESİZ Sena Investigation of Acute Phase Reactants and Antioxidant Capacity in Calves Infected with Cryptosporidium parvum. (2017): 481 - 485. |
| MLA | ÇENESİZ METİN,sagkan ozturk aliye,DALĞIN Duygu,Yarim Gul Fatma,ÇİFTCİ GÜLAY,ÖZDEMİR Ramazan,GÜZEL Murat,Kazak Filiz,ÇENESİZ Sena Investigation of Acute Phase Reactants and Antioxidant Capacity in Calves Infected with Cryptosporidium parvum. , 2017, ss.481 - 485. |
| AMA | ÇENESİZ M,sagkan ozturk a,DALĞIN D,Yarim G,ÇİFTCİ G,ÖZDEMİR R,GÜZEL M,Kazak F,ÇENESİZ S Investigation of Acute Phase Reactants and Antioxidant Capacity in Calves Infected with Cryptosporidium parvum. . 2017; 481 - 485. |
| Vancouver | ÇENESİZ M,sagkan ozturk a,DALĞIN D,Yarim G,ÇİFTCİ G,ÖZDEMİR R,GÜZEL M,Kazak F,ÇENESİZ S Investigation of Acute Phase Reactants and Antioxidant Capacity in Calves Infected with Cryptosporidium parvum. . 2017; 481 - 485. |
| IEEE | ÇENESİZ M,sagkan ozturk a,DALĞIN D,Yarim G,ÇİFTCİ G,ÖZDEMİR R,GÜZEL M,Kazak F,ÇENESİZ S "Investigation of Acute Phase Reactants and Antioxidant Capacity in Calves Infected with Cryptosporidium parvum." , ss.481 - 485, 2017. |
| ISNAD | ÇENESİZ, METİN vd. "Investigation of Acute Phase Reactants and Antioxidant Capacity in Calves Infected with Cryptosporidium parvum". (2017), 481-485. |
| APA | ÇENESİZ M, sagkan ozturk a, DALĞIN D, Yarim G, ÇİFTCİ G, ÖZDEMİR R, GÜZEL M, Kazak F, ÇENESİZ S (2017). Investigation of Acute Phase Reactants and Antioxidant Capacity in Calves Infected with Cryptosporidium parvum. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 23(3), 481 - 485. |
| Chicago | ÇENESİZ METİN,sagkan ozturk aliye,DALĞIN Duygu,Yarim Gul Fatma,ÇİFTCİ GÜLAY,ÖZDEMİR Ramazan,GÜZEL Murat,Kazak Filiz,ÇENESİZ Sena Investigation of Acute Phase Reactants and Antioxidant Capacity in Calves Infected with Cryptosporidium parvum. Kafkas Üniversitesi Veteriner Fakültesi Dergisi 23, no.3 (2017): 481 - 485. |
| MLA | ÇENESİZ METİN,sagkan ozturk aliye,DALĞIN Duygu,Yarim Gul Fatma,ÇİFTCİ GÜLAY,ÖZDEMİR Ramazan,GÜZEL Murat,Kazak Filiz,ÇENESİZ Sena Investigation of Acute Phase Reactants and Antioxidant Capacity in Calves Infected with Cryptosporidium parvum. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, vol.23, no.3, 2017, ss.481 - 485. |
| AMA | ÇENESİZ M,sagkan ozturk a,DALĞIN D,Yarim G,ÇİFTCİ G,ÖZDEMİR R,GÜZEL M,Kazak F,ÇENESİZ S Investigation of Acute Phase Reactants and Antioxidant Capacity in Calves Infected with Cryptosporidium parvum. Kafkas Üniversitesi Veteriner Fakültesi Dergisi. 2017; 23(3): 481 - 485. |
| Vancouver | ÇENESİZ M,sagkan ozturk a,DALĞIN D,Yarim G,ÇİFTCİ G,ÖZDEMİR R,GÜZEL M,Kazak F,ÇENESİZ S Investigation of Acute Phase Reactants and Antioxidant Capacity in Calves Infected with Cryptosporidium parvum. Kafkas Üniversitesi Veteriner Fakültesi Dergisi. 2017; 23(3): 481 - 485. |
| IEEE | ÇENESİZ M,sagkan ozturk a,DALĞIN D,Yarim G,ÇİFTCİ G,ÖZDEMİR R,GÜZEL M,Kazak F,ÇENESİZ S "Investigation of Acute Phase Reactants and Antioxidant Capacity in Calves Infected with Cryptosporidium parvum." Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 23, ss.481 - 485, 2017. |
| ISNAD | ÇENESİZ, METİN vd. "Investigation of Acute Phase Reactants and Antioxidant Capacity in Calves Infected with Cryptosporidium parvum". Kafkas Üniversitesi Veteriner Fakültesi Dergisi 23/3 (2017), 481-485. |
