This study was planned to investigate the applicability of soilless culture technique for table grape cultivation. In the study, Yalova incisi, Trakya İlkeren and Prima cultivars were grown using Cocopeat and Torf:Perlite (1:2) medium wit h modified Hoagland solution under soilless culture conditions under plastic cover. In the first year of the work (2014), sh o o t length, number of nodes and shoot diameter; in the second and third years, the effects of the applications on phenological characteristics, grape yield, cluster and 100 berry weight, must characteristics and mineral nutrient level of the leaves were examined. During the first development period, when only one shoot grows, the longest shoot length (182.5 cm) was fo un d in the Trakya İlkeren and the largest diameter (6.42 mm) was found in the Cocopeat medium. In the second and third crop years (2015 and 2016), the highest grape yields were observed in Prima (6731 and 4204 g vine-1, respectively) and Trakya İlkeren (6577 and 3941 g vine-1, respectively). In both years, the highest cluster weight values were obtained from Trakya İlkeren (506.3 and 394.1 g, respectively). In terms of yield, cluster weight and trunk diameter, Torf: Perlite (1: 2) medium gave higher values than Cocopeat medium. The results obtained from these and other traits have shown that Prima and Trakya İlkeren cultivars grown in the soilless culture medium can achieve higher yield and sufficient qualities than those grown in open and conventional conditions. Additionally, in the research con ditions, both growth medium that have been tested can be suggested for table grape cultivation in soilless culture.