Yıl: 2016 Cilt: 44 Sayı: 6 Sayfa Aralığı: 312 - 316 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Evaluation of the Analgesic Efficacy of Dexketoprofen Added to Paracetamol

Öz:
Amaç: Multimodal analjezi postoperatif ağrının tedavisinde tercih edilen bir metodtur, analjezik ilaçların aditif etkisi yan etkilerden kaçınmaya olanak sağlar. Bu çalışmada postoperatif ağrıda deksketoprofen ve parasetamol kombinasyonunun etkilerinin karşılaştı- rılması amaçlandı. Yöntemler: Non-malin jinekolojik laparatomi geçirecek 96 hasta çalışmaya dahil edildi. Hastalar randomize 3 gruba ayrıldı. Grup D'ye operasyon bitiminden 15 dakika önce, postoperatif 8. ve 16. saatlerde 50 mg intravenöz deksktoprofen verildi. Grup P'ye 1 gr intravenöz parasetamol, Grup DP'ye 500 mgr parasetamol + 25 mgr deksketoprofen intravenöz olarak aynı zamanlarda verildi. Tüm hastalara postoperatif morfin infüzyonu uygulandı. Postoperatif 24. saatin sonunda total morfin tüketimi, visual analog skala, hasta memnuniyeti ve yan etkiler değerlendirildi. Bulgular: Grup DP'deki 24.saatteki vizüel analog skala diğer gruplara göre düşük bulundu, ve bu düşüklük Grup D ile karşı- laştırıldığında istatiksel yönden anlamlı idi. Her 3 grup arasında morfin tüketimi açısından fark bulunmadı. En az sayıda yan etki Grup DP idi. Sonuç: Jinekolojik abdominal cerrahide deksketoprofen ve parasetamol birlikteliğinin morfinle kullanımı iyi analjezi ve daha az yan etki sağlamaktadır.
Anahtar Kelime:

Konular: Anestezi

Parasetamole Eklenen Deksketoprofenin Analjezik Etkisinin Değerlendirilmesi

Öz:
Objective: Multimodal analgesic methods are preferred for thetreatment of postoperative pain; as a result, the additive effects ofanalgesics are provided while probable side effects are avoided. Thecurrent study aimed to compare the effects of the combination ofdexketoprofen and paracetamol with regard to postoperative paintherapy.Methods: Ninety-six patients who underwent non-malignant gynaecologicallaparotomy operations were included in this study.Patients were randomized into 3 groups. Group D received 50 mgintravenous dexketoprofen 15 minutes before the end of the operationand 8 and 16 hours after the operation. Group P received 1 gintravenous paracetamol and Group DP received the combinationof 500 mg paracetamol and 25 mg dexketoprofen at the same timeintervals. All patients received morphine infusion after operation.Total morphine consumption at 24 hours, visual analog scale, patientsatisfaction and side effects were investigated.Results: Comparison of the visual analog scale scores revealed thatthe Group DP presented lower scores at 24th hours comparedto the other groups; and the difference between Group DP andGroup D was statistically significant. Total morphine consumptionwas not significantly different between the three groups. Theminimum number of side effects was observed in the Group DP.Conclusion: Co-administration of paracetamol, dexketoprofenand morphine provided good analgesia and fewer side effects ingynaecological abdominal surgery
Anahtar Kelime:

Konular: Anestezi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA CEYHAN D, Bilir A, GÜLEÇ M (2016). Evaluation of the Analgesic Efficacy of Dexketoprofen Added to Paracetamol. , 312 - 316.
Chicago CEYHAN Dilek,Bilir Ayten,GÜLEÇ MEHMET SACİT Evaluation of the Analgesic Efficacy of Dexketoprofen Added to Paracetamol. (2016): 312 - 316.
MLA CEYHAN Dilek,Bilir Ayten,GÜLEÇ MEHMET SACİT Evaluation of the Analgesic Efficacy of Dexketoprofen Added to Paracetamol. , 2016, ss.312 - 316.
AMA CEYHAN D,Bilir A,GÜLEÇ M Evaluation of the Analgesic Efficacy of Dexketoprofen Added to Paracetamol. . 2016; 312 - 316.
Vancouver CEYHAN D,Bilir A,GÜLEÇ M Evaluation of the Analgesic Efficacy of Dexketoprofen Added to Paracetamol. . 2016; 312 - 316.
IEEE CEYHAN D,Bilir A,GÜLEÇ M "Evaluation of the Analgesic Efficacy of Dexketoprofen Added to Paracetamol." , ss.312 - 316, 2016.
ISNAD CEYHAN, Dilek vd. "Evaluation of the Analgesic Efficacy of Dexketoprofen Added to Paracetamol". (2016), 312-316.
APA CEYHAN D, Bilir A, GÜLEÇ M (2016). Evaluation of the Analgesic Efficacy of Dexketoprofen Added to Paracetamol. Turkish Journal of Anaesthesiology and Reanimation, 44(6), 312 - 316.
Chicago CEYHAN Dilek,Bilir Ayten,GÜLEÇ MEHMET SACİT Evaluation of the Analgesic Efficacy of Dexketoprofen Added to Paracetamol. Turkish Journal of Anaesthesiology and Reanimation 44, no.6 (2016): 312 - 316.
MLA CEYHAN Dilek,Bilir Ayten,GÜLEÇ MEHMET SACİT Evaluation of the Analgesic Efficacy of Dexketoprofen Added to Paracetamol. Turkish Journal of Anaesthesiology and Reanimation, vol.44, no.6, 2016, ss.312 - 316.
AMA CEYHAN D,Bilir A,GÜLEÇ M Evaluation of the Analgesic Efficacy of Dexketoprofen Added to Paracetamol. Turkish Journal of Anaesthesiology and Reanimation. 2016; 44(6): 312 - 316.
Vancouver CEYHAN D,Bilir A,GÜLEÇ M Evaluation of the Analgesic Efficacy of Dexketoprofen Added to Paracetamol. Turkish Journal of Anaesthesiology and Reanimation. 2016; 44(6): 312 - 316.
IEEE CEYHAN D,Bilir A,GÜLEÇ M "Evaluation of the Analgesic Efficacy of Dexketoprofen Added to Paracetamol." Turkish Journal of Anaesthesiology and Reanimation, 44, ss.312 - 316, 2016.
ISNAD CEYHAN, Dilek vd. "Evaluation of the Analgesic Efficacy of Dexketoprofen Added to Paracetamol". Turkish Journal of Anaesthesiology and Reanimation 44/6 (2016), 312-316.