The relationship between serum lipid parameters and renal frame count in hypertensive patients with normal renal functions

yildirim, erkan; İpek, Emrah; Yolcu, Mustafa

The relationship between serum lipid parameters and renal frame count in hypertensive patients with normal renal functions

Emrah İPEK, (Department of Cardiology, Erzurum Regional Training and Research Hospital, Erzurum, Turkey)

Mustafa YOLCU, (Department of Cardiology, Arel University Faculty of Medicine, İstanbul, Turkey)

Erkan YILDIRIM (Department of Cardiology, Erzurum Regional Training and Research Hospital, Erzurum, Turkey)

Türk Kardiyoloji Derneği Arşivi

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Yıl: 2017 Cilt: 45 Sayı: 4 Sayfa Aralığı: 348 - 354 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

The relationship between serum lipid parameters and renal frame count in hypertensive patients with normal renal functions

Öz:

Amaç: Ateroskleroz renovasküler hastalığa katkıda bulunabilirve yüksek kolesterol düzeyleri hastalığın ilerlemesi içinrisk faktörüdür. Renal kare sayısı (RKS) ana renal arter vesegmental dallarındaki makrovasküler kan akımını gösterennesnel bir yöntemdir. Bu çalışmada, serum lipit parametreleriile RKS arasındaki ilişki incelendi.Yöntemler: Kesitsel olarak kurgulanan calışmaya 116 hipertansifhasta alındı ve hastalar serum LDL kolesterol seviyelerinegöre iki gruba ayrıldı. Grup 1'de LDL<130 mg/dL olan 60,grup 2'de ise LDL seviyesi 130 mg/dL ve üzeri olan 56 hastamevcuttu. Hastalar serum toplam kolesterol (TK) seviyelerinegöre de iki gruba ayrıldı (TK <200 mg/dL olan 52 hasta grup1'de, TK 200 mg/dL ve üzeri olan 64 hasta grup 2'de).Bulgular: Ortalama RKS, grup 2'de grup 1'e kıyasla dahayüksekti (p<0.001). Her iki böbreğin RFK'ları ayrı ayrı grup2'de grup 1'e göre daha yüksekti (sırasıyla, p<0.001 vep=0.023). Toplam kolesterol temelli gruplarda da benzersonuçlar elde edildi. RKS, sigara (paket yıl), TK ve LDL ileanlamlı pozitif ilişkiye sahipti (sırasıyla, r=0.326, p=0.035;r=0.393, p=0.010; r=0.386, p=0.012). Çoklu değişkenli lineerregresyon analizinde LDL, TK, sigara ve kreatinin klirensi,RKS'nin bağımsız tahmin ettiricileri olarak bulundu.Sonuç: Normal böbrek işlevi olan hipertansif hastalarda LDL,TK ve sigara RKS'yı tahmin ettirebilir ve yoğun risk faktörümodifikasyonu böbrek yetersizliği riskini azaltabilir.

Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi

Normal böbrek işlevi olan hipertansif hastalarda serum lipit parametreleri ile renal kare sayıları arasındaki ilişki

Öz:

Objective: Atherosclerosis can contribute to renovasculardisease, and high cholesterol level is an independent risk factorfor disease progression. Renal frame count (RFC) is anobjective angiographic method of measuring macrovascularblood flow in the main renal artery and its segmental branches.The aim of the present study was to demonstrate relationshipbetween serum lipid parameters and RFC.Methods: In this cross-sectional study, 116 hypertensive patientswere allocated into 2 groups according to serum low-density lipoprotein(LDL) levels. Group 1 comprised 60 patients with LDL<130 mg/dL and Group 2 consisted of 56 individuals with LDL>=130 mg/dL. The patients were also divided into 2 groups accordingto total cholesterol (TC) levels (52 patients in group withTC <200 mg/dL and 64 patients in group with TC >=200 mg/dL).Results: Group 2 had higher mean RFC than Group 1(p<0.001). RFC of both kidneys in Group 2 was significantlyhigher than results in Group 1 (p<0.001 and p=0.023, respectively).We found similar significant results in comparison ofTC-based patient groups. RFC had positive correlation withsmoking, TC, and LDL (r=0.326, p=0.035; r=0.393, p=0.010;and r=0.386, p=0.012, respectively). In multivariate linearregression analysis, LDL, TC, smoking, and creatinine clearancewere independent predictors of RFC.Conclusion: In conclusion, in hypertensive patients with normalrenal function, LDL, TC, and smoking may be predictorsof RFC and aggressive risk factor modification may help toreduce the risk of renal failure.

Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	İpek E, Yolcu M, yildirim e (2017). The relationship between serum lipid parameters and renal frame count in hypertensive patients with normal renal functions. , 348 - 354.
Chicago	İpek Emrah,Yolcu Mustafa,yildirim erkan The relationship between serum lipid parameters and renal frame count in hypertensive patients with normal renal functions. (2017): 348 - 354.
MLA	İpek Emrah,Yolcu Mustafa,yildirim erkan The relationship between serum lipid parameters and renal frame count in hypertensive patients with normal renal functions. , 2017, ss.348 - 354.
AMA	İpek E,Yolcu M,yildirim e The relationship between serum lipid parameters and renal frame count in hypertensive patients with normal renal functions. . 2017; 348 - 354.
Vancouver	İpek E,Yolcu M,yildirim e The relationship between serum lipid parameters and renal frame count in hypertensive patients with normal renal functions. . 2017; 348 - 354.
IEEE	İpek E,Yolcu M,yildirim e "The relationship between serum lipid parameters and renal frame count in hypertensive patients with normal renal functions." , ss.348 - 354, 2017.
ISNAD	İpek, Emrah vd. "The relationship between serum lipid parameters and renal frame count in hypertensive patients with normal renal functions". (2017), 348-354.

APA	İpek E, Yolcu M, yildirim e (2017). The relationship between serum lipid parameters and renal frame count in hypertensive patients with normal renal functions. Türk Kardiyoloji Derneği Arşivi, 45(4), 348 - 354.
Chicago	İpek Emrah,Yolcu Mustafa,yildirim erkan The relationship between serum lipid parameters and renal frame count in hypertensive patients with normal renal functions. Türk Kardiyoloji Derneği Arşivi 45, no.4 (2017): 348 - 354.
MLA	İpek Emrah,Yolcu Mustafa,yildirim erkan The relationship between serum lipid parameters and renal frame count in hypertensive patients with normal renal functions. Türk Kardiyoloji Derneği Arşivi, vol.45, no.4, 2017, ss.348 - 354.
AMA	İpek E,Yolcu M,yildirim e The relationship between serum lipid parameters and renal frame count in hypertensive patients with normal renal functions. Türk Kardiyoloji Derneği Arşivi. 2017; 45(4): 348 - 354.
Vancouver	İpek E,Yolcu M,yildirim e The relationship between serum lipid parameters and renal frame count in hypertensive patients with normal renal functions. Türk Kardiyoloji Derneği Arşivi. 2017; 45(4): 348 - 354.
IEEE	İpek E,Yolcu M,yildirim e "The relationship between serum lipid parameters and renal frame count in hypertensive patients with normal renal functions." Türk Kardiyoloji Derneği Arşivi, 45, ss.348 - 354, 2017.
ISNAD	İpek, Emrah vd. "The relationship between serum lipid parameters and renal frame count in hypertensive patients with normal renal functions". Türk Kardiyoloji Derneği Arşivi 45/4 (2017), 348-354.