Epidemiology, pathophysiology, clinical evaluation, and treatment of carbon monoxide poisoning in child, infant, and fetus

KARAKURT, Yakup; ARICA, Vefik; Dağ, Hüseyin; GOZUBUYUK, Atilla Alp; Kaçar, Alper

Epidemiology, pathophysiology, clinical evaluation, and treatment of carbon monoxide poisoning in child, infant, and fetus

Atilla Alp GOZUBUYUK, (Department of Pediatrics, Okmeydani Training and Research Hospital, Istanbul, Turkey)

Hüseyin DAĞ, (Department of Pediatrics, Okmeydani Training and Research Hospital, Istanbul, Turkey)

Alper KAÇAR, (Department of Pediatrics, Okmeydani Training and Research Hospital, Istanbul, Turkey)

Yakup KARAKURT, (Department of Pediatrics, Okmeydani Training and Research Hospital, Istanbul, Turkey)

Vefik ARICA (Department of Pediatrics, Okmeydani Training and Research Hospital, Istanbul, Turkey)

İstanbul Kuzey Klinikleri

6 1

Yıl: 2017 Cilt: 4 Sayı: 1 Sayfa Aralığı: 100 - 107 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Epidemiology, pathophysiology, clinical evaluation, and treatment of carbon monoxide poisoning in child, infant, and fetus

Öz:

Carbon monoxide (CO) poisoning is one of the most common types of poisoning causing death worldwide. In our country, it occurs particularly during winter as a result of leak from stove or water heater, or as result of inhalation during a fire. Although most poisonings occur accidentally, some cases are suicide attempt. As CO is a substance that is not visible and has no taste or smell and is therefore difficult to detect, the gas can be a "silent killer" that is not noticed until effects develop. CO reacts with oxygen, creating carboxy hemoglobin (COHb), which leads to tissue hypoxia. In addition, it has direct effect of causing cellular damage. Although symptoms of acute poisoning are most commonly observed in patients admitted to emergency rooms, effects of chronic exposure to CO can also seen. Clinically, although it affects all organ systems, involvement of central nervous system (CNS) and cardiovascular system is predominant. Most common poisoning symptoms are weakness, dizziness, headache, nausea, and nonspecific flu-like symptoms, like vomiting. Depending on severity of exposure, seizures, syncope, and arrhythmia may also be observed. In pregnant women, fetus can be harmed with relatively low level of COHb. Poisoning in infants has a more severe course than seen in other age groups. Symptoms must be associated with cause of poisoning, and careful anamnesis and treatment must be conducted quickly. Oxygen is the antidote for CO. It is administered through a mask in the form of normobaric oxygen therapy or through specific devices in the form of hyperbaric oxygen therapy. In this review, clinical data and current diagnostic and therapeutic approaches concerning CO poisoning are discussed.

Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	GOZUBUYUK A, Dağ H, Kaçar A, KARAKURT Y, ARICA V (2017). Epidemiology, pathophysiology, clinical evaluation, and treatment of carbon monoxide poisoning in child, infant, and fetus. , 100 - 107.
Chicago	GOZUBUYUK Atilla Alp,Dağ Hüseyin,Kaçar Alper,KARAKURT Yakup,ARICA Vefik Epidemiology, pathophysiology, clinical evaluation, and treatment of carbon monoxide poisoning in child, infant, and fetus. (2017): 100 - 107.
MLA	GOZUBUYUK Atilla Alp,Dağ Hüseyin,Kaçar Alper,KARAKURT Yakup,ARICA Vefik Epidemiology, pathophysiology, clinical evaluation, and treatment of carbon monoxide poisoning in child, infant, and fetus. , 2017, ss.100 - 107.
AMA	GOZUBUYUK A,Dağ H,Kaçar A,KARAKURT Y,ARICA V Epidemiology, pathophysiology, clinical evaluation, and treatment of carbon monoxide poisoning in child, infant, and fetus. . 2017; 100 - 107.
Vancouver	GOZUBUYUK A,Dağ H,Kaçar A,KARAKURT Y,ARICA V Epidemiology, pathophysiology, clinical evaluation, and treatment of carbon monoxide poisoning in child, infant, and fetus. . 2017; 100 - 107.
IEEE	GOZUBUYUK A,Dağ H,Kaçar A,KARAKURT Y,ARICA V "Epidemiology, pathophysiology, clinical evaluation, and treatment of carbon monoxide poisoning in child, infant, and fetus." , ss.100 - 107, 2017.
ISNAD	GOZUBUYUK, Atilla Alp vd. "Epidemiology, pathophysiology, clinical evaluation, and treatment of carbon monoxide poisoning in child, infant, and fetus". (2017), 100-107.

APA	GOZUBUYUK A, Dağ H, Kaçar A, KARAKURT Y, ARICA V (2017). Epidemiology, pathophysiology, clinical evaluation, and treatment of carbon monoxide poisoning in child, infant, and fetus. İstanbul Kuzey Klinikleri, 4(1), 100 - 107.
Chicago	GOZUBUYUK Atilla Alp,Dağ Hüseyin,Kaçar Alper,KARAKURT Yakup,ARICA Vefik Epidemiology, pathophysiology, clinical evaluation, and treatment of carbon monoxide poisoning in child, infant, and fetus. İstanbul Kuzey Klinikleri 4, no.1 (2017): 100 - 107.
MLA	GOZUBUYUK Atilla Alp,Dağ Hüseyin,Kaçar Alper,KARAKURT Yakup,ARICA Vefik Epidemiology, pathophysiology, clinical evaluation, and treatment of carbon monoxide poisoning in child, infant, and fetus. İstanbul Kuzey Klinikleri, vol.4, no.1, 2017, ss.100 - 107.
AMA	GOZUBUYUK A,Dağ H,Kaçar A,KARAKURT Y,ARICA V Epidemiology, pathophysiology, clinical evaluation, and treatment of carbon monoxide poisoning in child, infant, and fetus. İstanbul Kuzey Klinikleri. 2017; 4(1): 100 - 107.
Vancouver	GOZUBUYUK A,Dağ H,Kaçar A,KARAKURT Y,ARICA V Epidemiology, pathophysiology, clinical evaluation, and treatment of carbon monoxide poisoning in child, infant, and fetus. İstanbul Kuzey Klinikleri. 2017; 4(1): 100 - 107.
IEEE	GOZUBUYUK A,Dağ H,Kaçar A,KARAKURT Y,ARICA V "Epidemiology, pathophysiology, clinical evaluation, and treatment of carbon monoxide poisoning in child, infant, and fetus." İstanbul Kuzey Klinikleri, 4, ss.100 - 107, 2017.
ISNAD	GOZUBUYUK, Atilla Alp vd. "Epidemiology, pathophysiology, clinical evaluation, and treatment of carbon monoxide poisoning in child, infant, and fetus". İstanbul Kuzey Klinikleri 4/1 (2017), 100-107.