In this report, we aimed to present successful treatment of premacular subhyaloidal hemorrhage secondary to Valsalva maneuver due to hyperemesis gravidarium in pregnancy with Nd:YAG laser hyaloidotomy. A 25 year-old women with 4-week pregnancy complained of painless and sudden vision loss in her right eye after an emesis and vomiting episode. In ophthalmological examination subhyaloidal hemorrhage in macular area was detected. Observation or surgical options was not preferred due to extend of subhyaloidal hemorrhage and fi rst trimester of pregnancy. Nd:YAG laser hyaloidotomi was applied. Drainage of subhyaloidal hemorrhage into the vitreous was started just after Nd: YAG laser hyaloidotomy and then cleaned completely within one week. Second case was 20 year-olds pregnant at 38 weeks complained painless sudden vision loss in her left eye after an episode of her contractions. In ophthalmological examination subhyaloidal hemorrhage was diagnosed. She gave birth to a healthy child with normal spontaneous delivery at the next day. Nd:YAG laser hyaloidotomi was applied 6 days after her presentation. Subhyaloid hemorrhage was started to drain into the vitreous just after the laser hyaloidotomy and cleaned completely within 2 weeks. YAG laser hyaloidotomy can be considered as a safe method with a quick effect in the treatment of subhyaloidal hemorrhage related to Valsalva maneuver in pregnancy.