The Urinary System Infections caused by Extended- Spectrum-B-Lactamase-producing Escherichia coli and Klebsiella pneumoniae Strains

taken, kerem

The Urinary System Infections caused by Extended- Spectrum-B-Lactamase-producing Escherichia coli and Klebsiella pneumoniae Strains

Kerem TAKEN (Department of Urology,)

Eastern Journal of Medicine

1 0

Yıl: 2016 Cilt: 21 Sayı: 1 Sayfa Aralığı: 31 - 35 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

The Urinary System Infections caused by Extended- Spectrum-B-Lactamase-producing Escherichia coli and Klebsiella pneumoniae Strains

Öz:

Production of ?-Lactamase enzymes is an important mechanism of resistance in Gram-negative bacteria. The aim of this study was to investigate the relationship between the Extended-Spectrum ?-Lactamase (ESBL)-positive Escherichia coli (E. coli) and Klebsiella pneumoniae (K. pneumoniae) strains isolated from the urine cultures and the underlying diseases and also to assess the antibiotic resistance. The bacteria were identified according to conventional methods including colony morphology, gram stains, oxidase test and biochemical tests (indole production, Triple Sugar Iron (TSI) agar, Simmon's Citrate agar, Christensen's Urea agar, and motility test medium). BD Phoenix automated system (Becton Dickinson, USA) was used for further identification of the bacteria that were identified as E. coli and K. pneumoniae and for assessing the resistance rates and ESBL production. A total of 401 E. coli and 58 K. pneumoniae strains were isolated from the urinary specimens. Of these, 159 (39.6%) of E. coli and 26 (44.8%) of K. pneumoniae strains were ESBL-positive. The most active antibiotics against ESBL-positive E. coli and K. pneumoniae strains were carbapenems. Underlying diseases were detected in a total of 148 ESBL-positive strains (80%), including 127 (79.8%) of E. coli and 21 (80.8%) of K. pneumoniae strains. Common underlying diseases were benign prostate hyperplasia (BPH), urolithiasis, neurogenic bladder, urethral stricture, vesicoureteral reflux (VUR), hypospadias, ureteropelvic junction (UPJ) obstruction, vesicointestinal fistula, and cystocele (p<0.05). In the treatment of urinary system infections, ESBL-positive E. coli and K. pneumoniae strains should be kept in mind and the underlying diseases should be studied and treated.

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APA	taken k (2016). The Urinary System Infections caused by Extended- Spectrum-B-Lactamase-producing Escherichia coli and Klebsiella pneumoniae Strains. , 31 - 35.
Chicago	taken kerem The Urinary System Infections caused by Extended- Spectrum-B-Lactamase-producing Escherichia coli and Klebsiella pneumoniae Strains. (2016): 31 - 35.
MLA	taken kerem The Urinary System Infections caused by Extended- Spectrum-B-Lactamase-producing Escherichia coli and Klebsiella pneumoniae Strains. , 2016, ss.31 - 35.
AMA	taken k The Urinary System Infections caused by Extended- Spectrum-B-Lactamase-producing Escherichia coli and Klebsiella pneumoniae Strains. . 2016; 31 - 35.
Vancouver	taken k The Urinary System Infections caused by Extended- Spectrum-B-Lactamase-producing Escherichia coli and Klebsiella pneumoniae Strains. . 2016; 31 - 35.
IEEE	taken k "The Urinary System Infections caused by Extended- Spectrum-B-Lactamase-producing Escherichia coli and Klebsiella pneumoniae Strains." , ss.31 - 35, 2016.
ISNAD	taken, kerem. "The Urinary System Infections caused by Extended- Spectrum-B-Lactamase-producing Escherichia coli and Klebsiella pneumoniae Strains". (2016), 31-35.

APA	taken k (2016). The Urinary System Infections caused by Extended- Spectrum-B-Lactamase-producing Escherichia coli and Klebsiella pneumoniae Strains. Eastern Journal of Medicine, 21(1), 31 - 35.
Chicago	taken kerem The Urinary System Infections caused by Extended- Spectrum-B-Lactamase-producing Escherichia coli and Klebsiella pneumoniae Strains. Eastern Journal of Medicine 21, no.1 (2016): 31 - 35.
MLA	taken kerem The Urinary System Infections caused by Extended- Spectrum-B-Lactamase-producing Escherichia coli and Klebsiella pneumoniae Strains. Eastern Journal of Medicine, vol.21, no.1, 2016, ss.31 - 35.
AMA	taken k The Urinary System Infections caused by Extended- Spectrum-B-Lactamase-producing Escherichia coli and Klebsiella pneumoniae Strains. Eastern Journal of Medicine. 2016; 21(1): 31 - 35.
Vancouver	taken k The Urinary System Infections caused by Extended- Spectrum-B-Lactamase-producing Escherichia coli and Klebsiella pneumoniae Strains. Eastern Journal of Medicine. 2016; 21(1): 31 - 35.
IEEE	taken k "The Urinary System Infections caused by Extended- Spectrum-B-Lactamase-producing Escherichia coli and Klebsiella pneumoniae Strains." Eastern Journal of Medicine, 21, ss.31 - 35, 2016.
ISNAD	taken, kerem. "The Urinary System Infections caused by Extended- Spectrum-B-Lactamase-producing Escherichia coli and Klebsiella pneumoniae Strains". Eastern Journal of Medicine 21/1 (2016), 31-35.