Antioxidant, Antigenotoxic, Antimicrobial Activities and Phytochemical Analysis of Dianthus carmelitarum

Rezzan ALİYAZICIOĞLU, (Department of Biochemistry, Faculty of Pharmacy, Karadeniz Technical University, 61080, Trabzon, Türkiye)
Selim DEMİR, (Department of Nutrition and Dietetics, Faculty of Health Science, Karadeniz Technical University, 61080, Trabzon, Türkiye)
Merve BADEM, (Department of Pharmacognosy, Faculty of Pharmacy, Karadeniz Technical University, 61080, Trabzon, Türkiye)
Sıla Özlem ŞENER, (Department of Pharmacognosy, Faculty of Pharmacy, Karadeniz Technical University, 61080, Trabzon, Türkiye)
Nuriye KORKMAZ, (Department of Biochemistry, Faculty of Pharmacy, Karadeniz Technical University, 61080, Trabzon, Türkiye)
Elif Ayazoğlu DEMİR, (Department of Chemistry, Faculty of Sciences, Karadeniz Technical University, 61080, Trabzon, Türkiye)
Ufuk ÖZGEN, (Department of Pharmacognosy, Faculty of Pharmacy, Karadeniz Technical University, 61080, Trabzon, Türkiye)
ŞENGÜL ALPAY KARAOĞLU, (Department of Biology, Faculty of Arts and Sciences, Recep Tayyip Erdogan University, 53100, Rize, Türkiye)
Yüksel ALİYAZICIOĞLU (Department of Medical Biochemistry, Faculty of Medicine, Karadeniz Technical University, 61080, Trabzon, Türkiye)
Records of Natural Products
12 0
Yıl: 2017 Cilt: 11 Sayı: 3 Sayfa Aralığı: 270 - 284 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Antioxidant, Antigenotoxic, Antimicrobial Activities and Phytochemical Analysis of Dianthus carmelitarum

Öz:
In this study, we investigated the phytochemical composition, antioxidant, antimicrobial, and antigenotoxic properties of the aqueous extract of Dianthus carmelitarum for the first time. The phenolic and volatile compounds, antioxidant, antimicrobial and antigenotoxic activities of the extract were determined by HPLC and SPME-GC-FID/MS, spectrophotometric, agar well diffusion methods and comet assay, respectively. The polyphenolic content and ferric reducing power values of the extract were found 12.6 ± 0.27 mg gallic acid and 238 ± 2.89 μM trolox equivalents per g sample, respectively. Syringaldehyde and chlorogenic acid were detected as major phenolic compounds, while terpenes were determined as major volatile compound. Dianthus carmelitarum extract especially exhibited moderate antimicrobial activity against Mycobacterium smegmatis. Extract reduced H2O2-induced DNA damage in a concentration dependent manner in fibroblast cells compared to positive control (only 20 μM H2O2 treatment). Dianthus carmelitarum can be considered in the food, cosmetic, and drug industries due to its antioxidant, antimicrobial, and antigenotoxic activities
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APA ALİYAZICIOĞLU R, Demir S, badem m, Turgut S, Korkmaz N, SEYAZ M, ÖZGEN U, Alpay Karaoğlu Ş, ALİYAZICIOĞLU Y (2017). Antioxidant, Antigenotoxic, Antimicrobial Activities and Phytochemical Analysis of Dianthus carmelitarum. , 270 - 284.
Chicago ALİYAZICIOĞLU Rezzan,Demir Selim,badem merve,Turgut Sıla,Korkmaz Nuriye,SEYAZ MEHTAP,ÖZGEN Ufuk,Alpay Karaoğlu Şengül,ALİYAZICIOĞLU Yüksel Antioxidant, Antigenotoxic, Antimicrobial Activities and Phytochemical Analysis of Dianthus carmelitarum. (2017): 270 - 284.
MLA ALİYAZICIOĞLU Rezzan,Demir Selim,badem merve,Turgut Sıla,Korkmaz Nuriye,SEYAZ MEHTAP,ÖZGEN Ufuk,Alpay Karaoğlu Şengül,ALİYAZICIOĞLU Yüksel Antioxidant, Antigenotoxic, Antimicrobial Activities and Phytochemical Analysis of Dianthus carmelitarum. , 2017, ss.270 - 284.
AMA ALİYAZICIOĞLU R,Demir S,badem m,Turgut S,Korkmaz N,SEYAZ M,ÖZGEN U,Alpay Karaoğlu Ş,ALİYAZICIOĞLU Y Antioxidant, Antigenotoxic, Antimicrobial Activities and Phytochemical Analysis of Dianthus carmelitarum. . 2017; 270 - 284.
Vancouver ALİYAZICIOĞLU R,Demir S,badem m,Turgut S,Korkmaz N,SEYAZ M,ÖZGEN U,Alpay Karaoğlu Ş,ALİYAZICIOĞLU Y Antioxidant, Antigenotoxic, Antimicrobial Activities and Phytochemical Analysis of Dianthus carmelitarum. . 2017; 270 - 284.
IEEE ALİYAZICIOĞLU R,Demir S,badem m,Turgut S,Korkmaz N,SEYAZ M,ÖZGEN U,Alpay Karaoğlu Ş,ALİYAZICIOĞLU Y "Antioxidant, Antigenotoxic, Antimicrobial Activities and Phytochemical Analysis of Dianthus carmelitarum." , ss.270 - 284, 2017.
ISNAD ALİYAZICIOĞLU, Rezzan vd. "Antioxidant, Antigenotoxic, Antimicrobial Activities and Phytochemical Analysis of Dianthus carmelitarum". (2017), 270-284.
APA ALİYAZICIOĞLU R, Demir S, badem m, Turgut S, Korkmaz N, SEYAZ M, ÖZGEN U, Alpay Karaoğlu Ş, ALİYAZICIOĞLU Y (2017). Antioxidant, Antigenotoxic, Antimicrobial Activities and Phytochemical Analysis of Dianthus carmelitarum. Records of Natural Products, 11(3), 270 - 284.
Chicago ALİYAZICIOĞLU Rezzan,Demir Selim,badem merve,Turgut Sıla,Korkmaz Nuriye,SEYAZ MEHTAP,ÖZGEN Ufuk,Alpay Karaoğlu Şengül,ALİYAZICIOĞLU Yüksel Antioxidant, Antigenotoxic, Antimicrobial Activities and Phytochemical Analysis of Dianthus carmelitarum. Records of Natural Products 11, no.3 (2017): 270 - 284.
MLA ALİYAZICIOĞLU Rezzan,Demir Selim,badem merve,Turgut Sıla,Korkmaz Nuriye,SEYAZ MEHTAP,ÖZGEN Ufuk,Alpay Karaoğlu Şengül,ALİYAZICIOĞLU Yüksel Antioxidant, Antigenotoxic, Antimicrobial Activities and Phytochemical Analysis of Dianthus carmelitarum. Records of Natural Products, vol.11, no.3, 2017, ss.270 - 284.
AMA ALİYAZICIOĞLU R,Demir S,badem m,Turgut S,Korkmaz N,SEYAZ M,ÖZGEN U,Alpay Karaoğlu Ş,ALİYAZICIOĞLU Y Antioxidant, Antigenotoxic, Antimicrobial Activities and Phytochemical Analysis of Dianthus carmelitarum. Records of Natural Products. 2017; 11(3): 270 - 284.
Vancouver ALİYAZICIOĞLU R,Demir S,badem m,Turgut S,Korkmaz N,SEYAZ M,ÖZGEN U,Alpay Karaoğlu Ş,ALİYAZICIOĞLU Y Antioxidant, Antigenotoxic, Antimicrobial Activities and Phytochemical Analysis of Dianthus carmelitarum. Records of Natural Products. 2017; 11(3): 270 - 284.
IEEE ALİYAZICIOĞLU R,Demir S,badem m,Turgut S,Korkmaz N,SEYAZ M,ÖZGEN U,Alpay Karaoğlu Ş,ALİYAZICIOĞLU Y "Antioxidant, Antigenotoxic, Antimicrobial Activities and Phytochemical Analysis of Dianthus carmelitarum." Records of Natural Products, 11, ss.270 - 284, 2017.
ISNAD ALİYAZICIOĞLU, Rezzan vd. "Antioxidant, Antigenotoxic, Antimicrobial Activities and Phytochemical Analysis of Dianthus carmelitarum". Records of Natural Products 11/3 (2017), 270-284.
Sayfa Oluşturulma Tarihi
23-04-2024 5:21

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