Yıl: 2017 Cilt: 6 Sayı: 1 Sayfa Aralığı: 108 - 111 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Viral Enfeksiyonlarda Telomeraz Aktivitesi

Öz:
Lineer kromozomların uçlarında yer alan telomer adı verilen yapılar kromozomların bütünlüğünü sağlar. Kısa telomerler, DNA hasarında oluşan sinyale benzer bir sinyal üreterek, gerek yaşlanmayı gerekse de programlı hücre ölümünü tetikler. Telomeraz enzimi de kısalan telomerleri onararak telomer zincirlerinin uzun kalmasını sağlar. Böylece hücrelerin bölünme kapasitesinde artış sağlanmış olur. İnsan ve hayvan onkojenik viruslarının, geliştirdikleri mekanizmalarla telomeraz enzimini yeniden aktive edebildikleri ispatlanmıştır. Bu derleme viral enfeksiyonlar ile telomeraz aktivitesi arasındaki ilişkinin incelendiği bir dizi çalışmadan hazırlanmıştır
Anahtar Kelime:

Konular: Ziraat Mühendisliği

Telomerase Activity in Viral Infections

Öz:
The structures at the ends of linear chromosomes called telomeres provide the integrity of the chromosomes. Short telomeres produce a signal similar to DNA damage and triggering both programmed cell aging and programmed cell death. Also, telomerase enzyme restores shortened telomeres and allowing telomerase chains to stay longer. Thus increases the cleavage capacity of the cells. It has been proven that human and animal oncogenic viruses can re-activate telomerase enzyme in the cell through their new developed mechanisms. This review is prepared with series of studies that is examined the relationship between viral infections and telomerase activity
Anahtar Kelime:

Konular: Ziraat Mühendisliği
Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık
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APA BAYRAM E, ÇENESİZ M, OKUR GÜMÜŞOVA S (2017). Viral Enfeksiyonlarda Telomeraz Aktivitesi. , 108 - 111.
Chicago BAYRAM Elif,ÇENESİZ METİN,OKUR GÜMÜŞOVA Semra Viral Enfeksiyonlarda Telomeraz Aktivitesi. (2017): 108 - 111.
MLA BAYRAM Elif,ÇENESİZ METİN,OKUR GÜMÜŞOVA Semra Viral Enfeksiyonlarda Telomeraz Aktivitesi. , 2017, ss.108 - 111.
AMA BAYRAM E,ÇENESİZ M,OKUR GÜMÜŞOVA S Viral Enfeksiyonlarda Telomeraz Aktivitesi. . 2017; 108 - 111.
Vancouver BAYRAM E,ÇENESİZ M,OKUR GÜMÜŞOVA S Viral Enfeksiyonlarda Telomeraz Aktivitesi. . 2017; 108 - 111.
IEEE BAYRAM E,ÇENESİZ M,OKUR GÜMÜŞOVA S "Viral Enfeksiyonlarda Telomeraz Aktivitesi." , ss.108 - 111, 2017.
ISNAD BAYRAM, Elif vd. "Viral Enfeksiyonlarda Telomeraz Aktivitesi". (2017), 108-111.
APA BAYRAM E, ÇENESİZ M, OKUR GÜMÜŞOVA S (2017). Viral Enfeksiyonlarda Telomeraz Aktivitesi. Harran Üniversitesi Veteriner Fakültesi Dergisi, 6(1), 108 - 111.
Chicago BAYRAM Elif,ÇENESİZ METİN,OKUR GÜMÜŞOVA Semra Viral Enfeksiyonlarda Telomeraz Aktivitesi. Harran Üniversitesi Veteriner Fakültesi Dergisi 6, no.1 (2017): 108 - 111.
MLA BAYRAM Elif,ÇENESİZ METİN,OKUR GÜMÜŞOVA Semra Viral Enfeksiyonlarda Telomeraz Aktivitesi. Harran Üniversitesi Veteriner Fakültesi Dergisi, vol.6, no.1, 2017, ss.108 - 111.
AMA BAYRAM E,ÇENESİZ M,OKUR GÜMÜŞOVA S Viral Enfeksiyonlarda Telomeraz Aktivitesi. Harran Üniversitesi Veteriner Fakültesi Dergisi. 2017; 6(1): 108 - 111.
Vancouver BAYRAM E,ÇENESİZ M,OKUR GÜMÜŞOVA S Viral Enfeksiyonlarda Telomeraz Aktivitesi. Harran Üniversitesi Veteriner Fakültesi Dergisi. 2017; 6(1): 108 - 111.
IEEE BAYRAM E,ÇENESİZ M,OKUR GÜMÜŞOVA S "Viral Enfeksiyonlarda Telomeraz Aktivitesi." Harran Üniversitesi Veteriner Fakültesi Dergisi, 6, ss.108 - 111, 2017.
ISNAD BAYRAM, Elif vd. "Viral Enfeksiyonlarda Telomeraz Aktivitesi". Harran Üniversitesi Veteriner Fakültesi Dergisi 6/1 (2017), 108-111.