Yıl: 2017 Cilt: 11 Sayı: 2 Sayfa Aralığı: 171 - 190 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Phytochemical Characterization and in vivo Anti-inflammatory and Wound-healing Activities of Argania spinosa (L.) Skeels Seed Oil

Öz:
The extracted oil of Argania spinosa (L.) was investigated in regard to its fatty acid composition and polyphenols byChromatography-Electro Spray Ionization-Quadruple Time Of Flight-Mass Spectrometry (UPLC-ESI-QTOF-MS), respectively. The reduction rate of topical inflammation of extracted oil was calculated using a mouse model. The skin toxicity of argan oil on intact and damaged skin was assessed using a rabbit model. The findings revealed a rich content of monounsaturated and polyunsaturated fatty acids and presence of phenolic acids. The oil exhibited a reduction of inflammation and facilitated a healing process without any irritation. The experimental study revealed that A. spinosa seed oil displays remarkable wound-healing and anti-inflammatory activities related to its chemical composition. Argan oil has positive potential for skin medicinal application
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • [1] J. F. Morton and G.L. Voss (1987). The argan tree (Argania sideroxylon, sapotaceae). A desert source of edible oil, Econ. Bot. 41, 221-233.
  • [2] M. Alifriqui (2004). L’écosystème de l’Arganier, Etude réalisée à la demande du Programme des Nations Unies pour le développement, PNUD, Maroc.
  • [3] P. Quezel and S. Santa (1963). Nouvelle flore de l’Algérie et des régions désertiques méridionales, Vol. II, Ed. Centre National de la Recherche Scientifique, Paris.
  • [4] O. Mhirit and P. Blero (1999). Le grand livre de la forêt marocaine, Mardaga, Sprimont, Belgique.
  • [5] Z. Charrouf and D. Guillaume (1998). Ethnoeconomical, ethnomedical, and phytochemical study of Argania spinosa (L.) Skeels : A Review, J. Ethnopharmacol. 67, 7-14.
  • [6] H. Bennani, A. Drissi, F. Giton, L. Kheuang, J. Fiet and A. Adlouni (2007). Antiproliferative effect of polyphenols and sterols of virgin argan oil on human prostate cancer cell lines, Cancer Detect. Prev. 31, 64–69.
  • [7] F. Khallouki, C. Younos, R. Soulimani, T. Oster, Z. Charrouf, B. Spiegelhalder, H. Bartsch and R.W. Owen (2003). Consumption of argan oil (Morocco) with its unique profile of fatty acids, tocopherols, squalene, sterols and phenolic compounds should confer valuable cancer chemopreventive effects, Europ. J. Cancer Prev. 12, 67-75.
  • [8] H. Berrougui, M. Cloutier, M. Isabelle and A. Khalil (2006). Phenolic-extract from argan oil (Argania spinosa L.) inhibits human low-density lipoprotein (LDL) oxidation and enhances cholesterol efflux from human THP-1 macrophages, Atherosclerosis 184, 389–396.
  • [9] A. Moukal (2004). L’arganier, Argania spinosa L. (skeels), usage thérapeutique, cosmétique et alimentaire, Phytothérapie 2, 135-141.
  • [10] A. Adlouni (2010). L’huile d’argan, de la nutrition à la santé, Phytothérapie 8, 89-97.
  • [11] N. El Alaoui (1999). Paysages, usages et voyages d'Argania spinosa (L.) Skeels (IXe-Xe siècles), J.A.T.B.A. 41,45-79.
  • [12] J. Belakhdar (1997). La pharmacopée marocaine traditionnelle, Médecine arabe ancienne et savoirs populaires, Ibis Press, France.
  • [13] M. Berrada (1972). Etude de la composition de l'huile d'argan, Al Awamia 42, 1–14.
  • [14] T. Rezanka and H. Rezanková (1999). Characterization of fatty acids and triacylglycerols in vegetable oils by gas chromatography and statistical analysis, Anal. Chim. Acta. 398, 253–26.
  • [15] M. Farines, J. Soulier, M. Charrouf and R. Soulier (1984). Etude de l'huile des graines d'Argania spinosa (L.); Sapotaceae. I. La fraction glycéridique, Rev. Fr. Corps Gras 31, 283–286.
  • [16] International standard organization ISO 5509 (2000). Animal and vegetable fats and oils – Preparation of Methyl Esters of Fatty Acids, International standard organization, Geneva.
  • [17] L.Yu, J. Perret, M. Harris, J. Wilson and S. Haley (2003). Antioxidant properties of bran extracts from ‘‘Akron’’ wheat grown at different locations, J. Agric. Food. Chem. 51, 1566–1570.
  • [18] C. Delporte, N. Backhouse, P. Salinas, A. San-Martín, J. Bórquez and A. Loyola (2003). Pharmacotoxicological study of new diterpenoids, Bioorgan. Med. Chem. 11, 1187–1190.
  • [19] G. Venzuela-Barra, C. Castro, C. Figueroa, A. Barriga, X. Silva, B. de las Heras, S. Hortelano and C. Delport (2015). Anti-inflammatory activity and phenolic profile of propolis from two locations in Región Metropolitana de Santiago Chile, J. Ethnopharmacol. 168, 37–44.
APA DAKİCHE H, KHALİ M, BOUTOUMİ H (2017). Phytochemical Characterization and in vivo Anti-inflammatory and Wound-healing Activities of Argania spinosa (L.) Skeels Seed Oil. , 171 - 190.
Chicago DAKİCHE Hadjira,KHALİ Mustapha,BOUTOUMİ Houcine Phytochemical Characterization and in vivo Anti-inflammatory and Wound-healing Activities of Argania spinosa (L.) Skeels Seed Oil. (2017): 171 - 190.
MLA DAKİCHE Hadjira,KHALİ Mustapha,BOUTOUMİ Houcine Phytochemical Characterization and in vivo Anti-inflammatory and Wound-healing Activities of Argania spinosa (L.) Skeels Seed Oil. , 2017, ss.171 - 190.
AMA DAKİCHE H,KHALİ M,BOUTOUMİ H Phytochemical Characterization and in vivo Anti-inflammatory and Wound-healing Activities of Argania spinosa (L.) Skeels Seed Oil. . 2017; 171 - 190.
Vancouver DAKİCHE H,KHALİ M,BOUTOUMİ H Phytochemical Characterization and in vivo Anti-inflammatory and Wound-healing Activities of Argania spinosa (L.) Skeels Seed Oil. . 2017; 171 - 190.
IEEE DAKİCHE H,KHALİ M,BOUTOUMİ H "Phytochemical Characterization and in vivo Anti-inflammatory and Wound-healing Activities of Argania spinosa (L.) Skeels Seed Oil." , ss.171 - 190, 2017.
ISNAD DAKİCHE, Hadjira vd. "Phytochemical Characterization and in vivo Anti-inflammatory and Wound-healing Activities of Argania spinosa (L.) Skeels Seed Oil". (2017), 171-190.
APA DAKİCHE H, KHALİ M, BOUTOUMİ H (2017). Phytochemical Characterization and in vivo Anti-inflammatory and Wound-healing Activities of Argania spinosa (L.) Skeels Seed Oil. Records of Natural Products, 11(2), 171 - 190.
Chicago DAKİCHE Hadjira,KHALİ Mustapha,BOUTOUMİ Houcine Phytochemical Characterization and in vivo Anti-inflammatory and Wound-healing Activities of Argania spinosa (L.) Skeels Seed Oil. Records of Natural Products 11, no.2 (2017): 171 - 190.
MLA DAKİCHE Hadjira,KHALİ Mustapha,BOUTOUMİ Houcine Phytochemical Characterization and in vivo Anti-inflammatory and Wound-healing Activities of Argania spinosa (L.) Skeels Seed Oil. Records of Natural Products, vol.11, no.2, 2017, ss.171 - 190.
AMA DAKİCHE H,KHALİ M,BOUTOUMİ H Phytochemical Characterization and in vivo Anti-inflammatory and Wound-healing Activities of Argania spinosa (L.) Skeels Seed Oil. Records of Natural Products. 2017; 11(2): 171 - 190.
Vancouver DAKİCHE H,KHALİ M,BOUTOUMİ H Phytochemical Characterization and in vivo Anti-inflammatory and Wound-healing Activities of Argania spinosa (L.) Skeels Seed Oil. Records of Natural Products. 2017; 11(2): 171 - 190.
IEEE DAKİCHE H,KHALİ M,BOUTOUMİ H "Phytochemical Characterization and in vivo Anti-inflammatory and Wound-healing Activities of Argania spinosa (L.) Skeels Seed Oil." Records of Natural Products, 11, ss.171 - 190, 2017.
ISNAD DAKİCHE, Hadjira vd. "Phytochemical Characterization and in vivo Anti-inflammatory and Wound-healing Activities of Argania spinosa (L.) Skeels Seed Oil". Records of Natural Products 11/2 (2017), 171-190.