The purpose of this study is to measure and to analyze the efficiency of cotton production activities on cotton producing farms. The goals of this study were focused on assessing data envelopment analysis, and on the technical and scale efficiency of cotton-production activities. One hundred and sixty-five representative cotton-producing farms were selected in the Söke Valley through a stratified random sampling method and then the relevant data were collected on the production activities of these selected farms. According to data envelopment analysis carried out considering all inputs, the number of farms found to be technically efficient was 20. The average technical efficiency of the 165 farms was calculated to be 83.90%. Differences between average efficiencies of the cotton-producing farms were evaluated using the Kruskal-Wallis test. All efficiency measures of the small-sized farms except for scale efficiency were found to be statistically different from farms of other sizes. When farms were grouped according to the educational levels of their owners, technical and pure technical efficiency measures were observed to be higher for farms whose owners were university graduates, but scale efficiency was found to be higher on farms owned by high school graduates. Nonetheless the differences in these efficiency measures grouped according to educational levels were not found to be statistically significant. When efficiency measures are assessed in terms of the location of the farm settlement, technical and pure technical efficiency measures are observed to be greatest in urban locations, while scale efficiency was higher in the villages. Statistical comparisons showed no significant differences between technical and scale efficiencies according to settlement location, but significant differences were found in pure technical efficiency measures.