TY  - JOUR
TI  - Clinical, Bacteriological, and Histopathological Aspects of Endotoxic Pyometra in Bitches
AB  - The object of this study was to compare the histopathologic change in uterus as well as the findings of clinical and bacteriological of twentyfourbitches with pyometra. Uterine lesions were grouped as acute endometritis, subacute endometritis, acute metritis, subacute metritis.Complete blood-count, blood biochemical parameters and toxin levels were determined. Only alkaline phosphatase levels were significantlydifferent between all groups (P<0.01). Blood endotoxin level was different between the acute and subacute endometritis groups (P<0.01),and subacute endometritis and acute metritis groups (P<0.01). All bitches in the subacute endometritis group recovered. Three bitches in theacute endometritis group, two bitches in the acute metritis group and one bitch in the subacute metritis group died. The blood endotoxinlevel was determined to be quite high in the dead bitches. There was a difference in the levels of blood urea nitrogen (P<0.05), creatinine(P<0.01), and toxin (P<0.0001) between the dead and surviving bitches. In conclusion, the prognosis of pyometra may be recovered inbitches diagnosed with subacute endometritis associated with low levels of circulating endotoxin. The endotoxemic bitches that have bloodendotoxin level above 0.96 EU/mL along with significantly increased alkaline phosphatase, blood urea nitrogen, and creatinine concentrationwould likely end up with a mortality outcome for acute endometritis, acute metritis, or subacute metritis. These parameters may serve asgood prognostic markers in bitches with pyometra.
AU  - Vural, Mehmet Rıfat
AU  - KÜPLÜLÜ, Şükrü
AU  - Demirel, Mürşide Ayşe
AU  - GÜNEN, Ziynet
AU  - Atalay VURAL, Sevil
AU  - KUTSAL, Osman
DO  - 10.9775/kvfd.2018.19675
PY  - 2018
JO  - Kafkas Üniversitesi Veteriner Fakültesi Dergisi
VL  - 24
IS  - 5
SN  - 1300-6045
SP  - 663
EP  - 671
DB  - TRDizin
UR  - http://search/yayin/detay/288119
ER  -