TY  - JOUR
TI  - Evaluation of platelet activating factor in neonatal calves with sepsis
AB  - Early diagnosis and treatment of sepsis are very important conditions in patients for their survival. Novel biomarkers such as platelet activating factor (PAF) have been found that it has an important role in sepsis process. The aim of this study is to determine the role of PAF in pathogenesis and the diagnosis importance in calves with sepsis. For this purposes, 30 neonatal calves with sepsis (sepsis group) and 10 healthy neonatal calves (control group) were used. Plasma samples were used to determine the PAF level with using bovine specific ELISA kits. Plasma concentration of PAF was found significantly higher (P < 0.01) in sepsis group compare to control group. We concluded that PAF has an important role in sepsis and it may have diagnostic value in calves with sepsis. Further studies are required to determine the importance of PAF as diagnostic and prognostic biomarker in calves with sepsis and evaluate the concentrations of these biomarker also in other disease states.
AU  - ÖZÇELİK M, Merve
AU  - YILDIZ, Ramazan
AU  - BESLEK, Mustafa
AU  - BİÇİCİ, Özlem
AU  - BEYDİLLİ, Yasemin
PY  - 2018
JO  - Veteriner Hekimler Derneği Dergisi
VL  - 89
IS  - 2
SN  - 0377-6395
SP  - 66
EP  - 73
DB  - TRDizin
UR  - http://search/yayin/detay/288345
ER  -