Combined treatment for gastric cancer: Immunological approach

ZHANDOSSOV, Olzhas; KOTEN, Avraam; KAUSSOVA, Galina

Combined treatment for gastric cancer: Immunological approach

Olzhas ZHANDOSSOV, (Department of Oncology, Kazakhstan Medical University High School of Public Health, Almaty, Kazakhstan)

Galina KAUSSOVA, (Department of Public Health and Social Sciences, Kazakhstan Medical University High School of Public Health, Almaty, Kazakhstan)

Avraam KOTEN (Department of Oncology, Medical Center “CarmelMC”, Haifa, Israel)

Turkish Journal of Gastroenterology

2 0

Yıl: 2018 Cilt: 29 Sayı: 2 Sayfa Aralığı: 151 - 156 Metin Dili: İngilizce İndeks Tarihi: 18-12-2018

Combined treatment for gastric cancer: Immunological approach

Öz:

Background/Aims: Gastric cancer is one of the most common oncological diseases. It can develop in any part of the stomach and spread to other organs, especially the esophagus, lungs, and liver. The aim of our study was to investigate the effectiveness of our pro-posed therapy.Materials and Methods: Our research promises more effective neoadjuvant therapy, including immunotherapy and multi-agent chemo-therapy. Of the 62 patients involved in our study, 32 underwent neoadjuvant chemotherapy in combination with surgery, whereas the rest underwent neoadjuvant chemoimmunotherapy with surgery.Results: Investigation of T-cell-mediated and humoral immunity in patients with gastric cancer over the course of treatment found a reduction of the main indices of cell-mediated and humoral immunity in the patients who underwent standard therapy, which greatly caused a decline of antitumor, anti-infective, and antitoxic protection of the patients’ organisms.Conclusion: This study can contribute to the development of new therapies for gastric cancer as well as other types of cancer.

Anahtar Kelime:

Konular: Gastroenteroloji ve Hepatoloji

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ZHANDOSSOV O, KAUSSOVA G, KOTEN A (2018). Combined treatment for gastric cancer: Immunological approach. , 151 - 156.
Chicago	ZHANDOSSOV Olzhas,KAUSSOVA Galina,KOTEN Avraam Combined treatment for gastric cancer: Immunological approach. (2018): 151 - 156.
MLA	ZHANDOSSOV Olzhas,KAUSSOVA Galina,KOTEN Avraam Combined treatment for gastric cancer: Immunological approach. , 2018, ss.151 - 156.
AMA	ZHANDOSSOV O,KAUSSOVA G,KOTEN A Combined treatment for gastric cancer: Immunological approach. . 2018; 151 - 156.
Vancouver	ZHANDOSSOV O,KAUSSOVA G,KOTEN A Combined treatment for gastric cancer: Immunological approach. . 2018; 151 - 156.
IEEE	ZHANDOSSOV O,KAUSSOVA G,KOTEN A "Combined treatment for gastric cancer: Immunological approach." , ss.151 - 156, 2018.
ISNAD	ZHANDOSSOV, Olzhas vd. "Combined treatment for gastric cancer: Immunological approach". (2018), 151-156.

APA	ZHANDOSSOV O, KAUSSOVA G, KOTEN A (2018). Combined treatment for gastric cancer: Immunological approach. Turkish Journal of Gastroenterology, 29(2), 151 - 156.
Chicago	ZHANDOSSOV Olzhas,KAUSSOVA Galina,KOTEN Avraam Combined treatment for gastric cancer: Immunological approach. Turkish Journal of Gastroenterology 29, no.2 (2018): 151 - 156.
MLA	ZHANDOSSOV Olzhas,KAUSSOVA Galina,KOTEN Avraam Combined treatment for gastric cancer: Immunological approach. Turkish Journal of Gastroenterology, vol.29, no.2, 2018, ss.151 - 156.
AMA	ZHANDOSSOV O,KAUSSOVA G,KOTEN A Combined treatment for gastric cancer: Immunological approach. Turkish Journal of Gastroenterology. 2018; 29(2): 151 - 156.
Vancouver	ZHANDOSSOV O,KAUSSOVA G,KOTEN A Combined treatment for gastric cancer: Immunological approach. Turkish Journal of Gastroenterology. 2018; 29(2): 151 - 156.
IEEE	ZHANDOSSOV O,KAUSSOVA G,KOTEN A "Combined treatment for gastric cancer: Immunological approach." Turkish Journal of Gastroenterology, 29, ss.151 - 156, 2018.
ISNAD	ZHANDOSSOV, Olzhas vd. "Combined treatment for gastric cancer: Immunological approach". Turkish Journal of Gastroenterology 29/2 (2018), 151-156.