Objective: In patients with expected airway difficulties, specificpreparatory and auxiliary equipment is required before generalanesthesia. The aim of this study was to compare the intubationefficacy of Macintosh laryngoscope with that of the McGrathMAC video laryngoscope in patients with cerebral palsy. Materials and Methods: The study was conducted in fortypatients (aged 4-15) with cerebral palsy who were scheduled toundergo dental treatment. Intubations were performed in patientsrandomly assigned to the McGrath MAC video laryngoscope orthe Macintosh laryngoscope. The characteristics of the patientsmean arterial blood pressure, heart rate, end-tidal carbon dioxide,and peripheral oxygen saturation were measured. The intubationsuccess, intubation time, Cormack and Lehane grades, number oftrials, need for neck extension, and complications were recorded.An independent sample t-test and a Mann–Whitney U test wereused. A chi-square test was used for the analysis of categoricaldata. The level of statistical significance was accepted as p <0.05.Results: When both groups were compared in terms of theglottic view, intubation time, and need for neck extension, therewas no significant difference (p = 0.542, p = 0.779, and p =1.000, respectively). All the intubations were performedsuccessfully at the first attempt in both groups, and nocomplications were recorded.Conclusion: Although our study included patients with cerebralpalsy, in which musculoskeletal anomalies are common,sufficient muscle relaxation for intubation after generalanesthesia was achieved in all the patients. There was noevidence of intubation difficulty in either group of patients, andcerebral palsy, with its existing deformities, did not affect theintubation success or complication rate. No additionaladvantages of using video laryngoscopy in patients with cerebralpalsy were found.