Blood Group Characteristics in Colorectal Cancers
Yıl: 2018 Cilt: 28 Sayı: 2 Sayfa Aralığı: 76 - 79 Metin Dili: İngilizce DOI: 10.4274/tjcd.00378 İndeks Tarihi: 04-01-2019
Blood Group Characteristics in Colorectal Cancers
Öz: Aim: Colorectal cancer (CRC) is the third most common cancer in the world. Tumors are most commonly located in the rectosigmoid region. Thereare many factors in the etiology such as age, geographical features, family history, obesity, diet, and history of malignancy. In the present study, weaimed to determine the effect of blood group characteristics, which play a role in the etiology of stomach cancer, on the etiology of CRC.Method: We retrospectively reviewed the files of patients who were diagnosed with CRC and operated in our center or at other centers and werefollowed postoperatively at our centers. Age, gender, histologic TNM stage (tumor, lymph node involvement, and metastasis), tumor-bearing colonsegment, ABO blood group, and Rh antigen were examined from the patients’ records.Results: There were 265 (54.5%) patients with lymph node involvement and 53 (10.9%) with liver metastasis. The most common tumor location wasthe rectum (n=203). When the blood group and Rh antigen subgroups were examined, blood group A was detected in 253 patients (52.1%), bloodgroup B in 115 patients (23.7%), blood group O in 78 patients (16%), and blood group AB in 40 patients. The incidence of colon cancer was found tobe significant in patients with A (+) blood group (p<0.001).Conclusion: As in stomach cancer, our findings show that the A (+) blood group is a risk factor in colorectal cancers, which have multifactorialetiology. Further genetic studies are needed.
Anahtar Kelime: Konular:
Kolorektal Kanserlerde Kan Grubu Özellikleri
Öz: Amaç: Kolorektal kanserler (KRK) tüm dünyada 3. en sık görülen kanser tipidir. Tümör lokalizasyonu en fazla rektosigmoid bölge yerleşimlidir. Etiyolojisinde yaş, coğrafi özellikler, aile öyküsü, obezite, diyet, malignite öyküsü gibi birçok faktör rol oynamaktadır. Çalışmamızda mide kanseri etiyolojisinde rol oynayan kan grubu özelliklerinin, kolorektal kanser etiyolojisi üzerine etkisini ortaya koymayı amaçladık. Yöntem: KRK tanısı ile tarafımızdan opere edilen ve dış merkezlerde opere edilip merkezlerimizde takip altında olan hastaların dosyaları retrospektif incelendi. Hastaların; yaş, cinsiyet, histopatolojik TNM (tümör, lenf nodu tutulumu ve metastaz varlığı) evreleri, tümörlü kolon segmentleri, hastaların ABO kan grupları ve Rh antijenleri incelendi. Bulgular: Çalışmamızdaki hastaların 265’inde (%54,5) lenf nodu pozitifliği, 53’ünde (%10,9) karaciğer metastazı tespit edildi. En sık tümör yerleşimi rektum (n=203) idi. Kan grubu ve Rh antijen alt grupları incelendiğinde; 253 hastada (%52,1) A kan grubu, 115 hastada (%23,7) B kan grubu, 78 hastada (%16) O kan grubu ve 40 hastada (%8,2) AB kan grubu saptanırken, 370 hastada (%76,1) Rh antijeni pozitif olarak tespit edildi. A (+) kan grubuna sahip hastalarda kolon kanseri görülme sıklığının anlamlı olduğu gözlendi (p<0,001). Sonuç: Birçok etiyolojik faktörün risk faktörü olarak kabul edildiği kolorektal kanserlerde, genetik çalışmalara ihtiyaç olmakla birlikte, A (+) kan grubunun mide kanserinde olduğu gibi risk faktörü olduğu sonucuna ulaştık.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Kahramanca Ş, anuk t, Yildirim A, KAYA İ (2018). Blood Group Characteristics in Colorectal Cancers. , 76 - 79. 10.4274/tjcd.00378 |
| Chicago | Kahramanca Şahin,anuk turgut,Yildirim Ali Cihat,KAYA İSMAİL OSKAY Blood Group Characteristics in Colorectal Cancers. (2018): 76 - 79. 10.4274/tjcd.00378 |
| MLA | Kahramanca Şahin,anuk turgut,Yildirim Ali Cihat,KAYA İSMAİL OSKAY Blood Group Characteristics in Colorectal Cancers. , 2018, ss.76 - 79. 10.4274/tjcd.00378 |
| AMA | Kahramanca Ş,anuk t,Yildirim A,KAYA İ Blood Group Characteristics in Colorectal Cancers. . 2018; 76 - 79. 10.4274/tjcd.00378 |
| Vancouver | Kahramanca Ş,anuk t,Yildirim A,KAYA İ Blood Group Characteristics in Colorectal Cancers. . 2018; 76 - 79. 10.4274/tjcd.00378 |
| IEEE | Kahramanca Ş,anuk t,Yildirim A,KAYA İ "Blood Group Characteristics in Colorectal Cancers." , ss.76 - 79, 2018. 10.4274/tjcd.00378 |
| ISNAD | Kahramanca, Şahin vd. "Blood Group Characteristics in Colorectal Cancers". (2018), 76-79. https://doi.org/10.4274/tjcd.00378 |
| APA | Kahramanca Ş, anuk t, Yildirim A, KAYA İ (2018). Blood Group Characteristics in Colorectal Cancers. Türk Kolon ve Rektum Hastalıkları Dergisi, 28(2), 76 - 79. 10.4274/tjcd.00378 |
| Chicago | Kahramanca Şahin,anuk turgut,Yildirim Ali Cihat,KAYA İSMAİL OSKAY Blood Group Characteristics in Colorectal Cancers. Türk Kolon ve Rektum Hastalıkları Dergisi 28, no.2 (2018): 76 - 79. 10.4274/tjcd.00378 |
| MLA | Kahramanca Şahin,anuk turgut,Yildirim Ali Cihat,KAYA İSMAİL OSKAY Blood Group Characteristics in Colorectal Cancers. Türk Kolon ve Rektum Hastalıkları Dergisi, vol.28, no.2, 2018, ss.76 - 79. 10.4274/tjcd.00378 |
| AMA | Kahramanca Ş,anuk t,Yildirim A,KAYA İ Blood Group Characteristics in Colorectal Cancers. Türk Kolon ve Rektum Hastalıkları Dergisi. 2018; 28(2): 76 - 79. 10.4274/tjcd.00378 |
| Vancouver | Kahramanca Ş,anuk t,Yildirim A,KAYA İ Blood Group Characteristics in Colorectal Cancers. Türk Kolon ve Rektum Hastalıkları Dergisi. 2018; 28(2): 76 - 79. 10.4274/tjcd.00378 |
| IEEE | Kahramanca Ş,anuk t,Yildirim A,KAYA İ "Blood Group Characteristics in Colorectal Cancers." Türk Kolon ve Rektum Hastalıkları Dergisi, 28, ss.76 - 79, 2018. 10.4274/tjcd.00378 |
| ISNAD | Kahramanca, Şahin vd. "Blood Group Characteristics in Colorectal Cancers". Türk Kolon ve Rektum Hastalıkları Dergisi 28/2 (2018), 76-79. https://doi.org/10.4274/tjcd.00378 |
