TY  - JOUR
TI  - Efficacy of tadalafil treatment on erectile dysfunction in patients under dutasteride treatment: A prospective non-randomized comparative study
AB  - Objective: In this study, we aimed to evaluate the efficacy of tadalafil in the management of erectile dysfunctionin patients under dutasteride medication for bladder outlet obstruction.Material and methods: In this study the data of consecutive patients that admitted to our outpatient clinicstreated with dutasteride for bladder outlet obstruction and tadalafil (10 or 20 mg on demand) for concomitantcomplaint of erectile dysfunction (ED) between October 2013 and March 2016 were evaluated. An agematchedcontrol group of patients treated with tadalafil for ED but did not receive any other medication foreither lower urinary tract symptoms (LUTS) or ED was also included. Groups were compared for tadalafilefficacy with International Index of Erectile Function (IIEF) scores.Results: Each one of the dutasteride and control groups included 104 patients. The groups were similar forpretreatment IIEF score, serum cholesterol, low-density lipoprotein (LDL), triglyceride and testosterone measurements.The number of hypertensive patients was comparable between two groups but the number of diabeticpatients were significantly higher in the control group. IIEF score improved significantly in both groupsfollowing tadalafil treatment but the difference between the two groups was not statistically significant.Conclusion: Tadalafil treatment provides significant improvement in erectile functions of patients underdutasteride treatment for bladder outlet obstruction. However, the current study does not focus on a populationof dutasteride induced ED and therefore a further prospective study on this issue would be helpful
AU  - ÖZKIDIK, Mete
AU  - GÖKCE, Mehmet İlker
AU  - YAMAN, MUHİDDİN ÖNDER
DO  - 10.5152/tud.2018.46666
PY  - 2018
JO  - Turkish Journal of Urology
VL  - 44
IS  - 4
SN  - 2149-3235
SP  - 294
EP  - 297
DB  - TRDizin
UR  - http://search/yayin/detay/290773
ER  -