TY  - JOUR
TI  - Chemical composition, antioxidant, anticholinesterase and anti-urease activities of Sideritis pisidica Boiss. & Heldr. endemic to Turkey
AB  - The objective of this study was to investigate the chemical composition, antioxidant, anticholinesterase and anti-urease activities of essential oil, hexane, acetone and methanol extracts of Sideritis pisidica Boiss. & Heldr. The essential oil and fatty acid composition were analyzed by GC and GC/MS. δ-Cadinene (19.5 %), T-cadinol (16.7 %) and β-cubebene (10.4 %) were identified as the main compounds of the essential oil whereas the most abundant compounds of fatty acids were found as linolenic (42.7 %), palmitic (31.3 %) and linoleic (13.4%) acids. The methanol extract demonstrated the highest antioxidant activity in all tests, except for metal chelating assay. The hexane extract was found to be significantly active in metal chelating (IC50: 22.97±1.36 µg/mL), acetylcholinesterase (62.54±0.88 %) and urease inhibitory (78.93±0.17 %) assays. These results show that the Sideritis pisidica could be used as the potential source of natural products in the food and pharmaceutical areas.
AU  - DURU, Mehmet Emin
AU  - YILDIRIM, HASAN
AU  - DEVECİ, EBRU
AU  - Tel-Çayan, Gulsen
DO  - 10.12991/mpj.2017.13
PY  - 2017
JO  - Marmara Pharmaceutical Journal
VL  - 21
IS  - 4
SN  - 1309-0801
SP  - 898
EP  - 905
DB  - TRDizin
UR  - http://search/yayin/detay/290964
ER  -