Yıl: 2014 Cilt: 22 Sayı: 4 Sayfa Aralığı: 181 - 185 Metin Dili: Türkçe İndeks Tarihi: 15-02-2019

MİKS VENÖZ OKSİJEN SATURASYONU VE KLİNİK ÖNEMİ

Öz:
Doku oksijenasyonunun global göstergesi olarak kabul edilen miks venöz oksijen saturasyonu özellikle kritik hasta takibinde hemodinamik monitorizasyonun ayrılmaz bir parçasıdır. Miks venöz oksijen saturasyonunun ölçümü için pulmoner arter kateterine gereksinim duyulması, sözü edilen hemodinamik parametrenin yaygın kullanılmasına büyük bir engel oluştursa da, hemodinamik olarak stabil olmayan hastaların ameliyat sırasında veya yoğun bakım ünitelerinde o anki doku oksijenizasyon düzeyinin saptanarak anlık müdahale olanağı tanıması nedeniyle halen birçok merkez tarafından kullanılmaktadır. Bu derlemede miks venöz oksijen saturasyonunun klinik önemine güncel bir bakış amaçlanmıştır.
Anahtar Kelime:

Konular: Anestezi

MIXED VENOUS OXYGEN SATURATION AND CLINICAL SIGNIFICANCE

Öz:
Mixed venous oxygen saturation known as global index of tissue oxygenation, is an integral part of hemodynamic monitoring for especially follow-up of critically-ill patients. Although it is needed to insert a pulmonary artery catheter to measure mixed venous oxygen saturation, and it is a major obstacle for the common usage of this hemodynamic parameter, currently it is used by multiple health care centres because of its ability to interfere instantly with the measured tissue oxygenation levels of unstable patients in operation room or intensive care units. In this review, it is aimed to have an updated look at the clinical significance of mixed venous oxygen saturation.
Anahtar Kelime:

Konular: Anestezi
Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık
  • Winters ME, McCurdy MT, Zilberstein J. Monitoring the critically ill Emergency Department patient. Emerg Med Clin N Am 2008; 26: 741-757.
  • Nebout S, Pirracchio R, Should we monitor ScVO2 in critically ill patients? Cardiol Res Pract 2012; 2012: 370697.
  • van Beest PA, Hofstra JJ, Schultz MJ, Boerma EC, Spronk PE, Kuiper MA. The incidence of low venous oxygen saturation on admission to the intensive care unit: a multi-center observational study in The Netherlands, Crit Care 2008; 12: R33.
  • Pinsky MR, Payen D. Functional Hemodynamic monitoring. Crit Care 2005; 9: 566-572.
  • Casserly B, Read R, Levy MM. Hemodynamic monitoring in sepsis Crit Care Nurs Clin N Am 2011; 23: 149-169.
  • Van Beest P, Wietasch G, Scheeren T, Spronk P, Kuiper M. Clinical review: use of venous oxygen saturations as a goal - a yet unfinished puzzle. Crit Care 2011; 15: 232.
  • Boldt J. Clinical review: Hemodynamic monitoring in the intensive care unit Crit Care 2002; 6: 52-59.
  • Ranucci M. Which cardiac surgical patients can benefit from placement of a pulmonary artery catheter? Crit Care 2006; 10: S6.
  • Velissaris D, Pierrakos C, Scolletta S, De Backer D, Vincent JL. High mix venous oxygen saturation levels do not exclude fluid responsiveness in critically ill septic patients. Crit Care 2011; 15: R177.
  • Edwards JD, Shoemaker WC, Vincent JL Oxygen Transport: Principles and Practice , Chapter 1 Overview: Evolution of the concept from Fick to the present day. p.1-14.
  • Chawla SL , Zia H, Gutierrez G et al. Lack of equivalence between central and mixed venous oxygen saturation Chest 2004; 126: 1891-1896.
  • Maddirala S, Khan A. Optimizing hemodynamic support in septic shock using central and mixed venous saturation. Crit Care Clin 2010; 26: 323-333.
  • Jones A, Puskarich M. Sepsis –Induced tissue hypoperfusion. Crit Care Nurs Clin N Am 2011; 23: 115-125.
  • Allashemi JA, Cecconi M, Hofer C. Cardiac output monitoring: an integrated perspective Crit Care 2011; 15: 214.
  • Payen D, Gayat E. Which general intensive care unit patients can benefit from placement of the pulmonary artery catheter? Crit Care 2006; 10: S7.
  • Maddirala S, Khan A. Optimizing hemodynamic support in septic shock using central and mixed venous oxygen saturation. Crit Care Clin 2010; 26: 323-333.
  • Sumimoto T, Takayam Y, Iwasaka T, et al. Mixed venous oxygen saturation as a guide to tissue oxygenation and prognosis in patients with acute myocardial infarction. Am Heart J 1991; 122: 27-33.
  • Holm J., Hakanson E, Vanky F, Svedjeholm R. Mixed venous oxygen saturation predicts short- and long term outcome after coronary artery bypass grafting surgery: a retrospective cohort analysis. Br J Anaesth 2011; 107: 344-350.
  • Lindholm L, Hansdottir V, Lundqvist M, Jeppsson A. The relationship between mixed venous and regional venous oxygen saturation during cardiopulmonary bypass. Perfusion 2002; 17: 133-139.
  • Pearse R, Dawson D. Fawcett J et al. Changes in central venous saturation after major surgery,an association with outcome Crit Care 2005; 9: R694-699.
  • Lequeux PY, Bouckaert Y , Sekkat H et al. Continuous mixed venous and central venous oxygen saturation in cardiac surgery with cardiopulmonary bypass Eur J Anaesthesiol 2010; 27: 295-299.
  • Keech J, Reed RL. Reliability of mixed venous oxygen saturation as an indicator of the oxygen extraction ratio demonstrated by a large patient data set J Trauma 2003; 54: 236-241.
  • Garstad IK, Sellevold OFM, Stenset R et al. Marked mixed venous desaturation during early mobilization after aortic valve surgery Anesth Analg 2004; 98: 311-317.
  • Nichols D, Nielsen ND Oxygen delivery and consumption: A macrocirculatory perspective Crit Care Clin 2010; 26: 239-253.
  • Donati A, Loggi S, Preiser JC et al: Goal-directed intraoperative therapy reduces morbidity and length of hospital stay in high-risk surgical patients. Chest 2007; 132: 1817-1824.
  • Pölönen P, Roukonen E, Hippelainen M et al. A prospective, randomized study of goal-oriented hemodynamic therapy in cardiac surgical patients. Anesth Analg 2000; 90: 1052-1059.
  • Dellinger RP, Levy MM, Rhodes A et al. Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock:2012 Crit Care Med 2013; 41: 2.
  • Van Beest PA , Van Ingen J, Boerma EC et al. No agreement of mixed venous and central venous saturation in sepsis, independent of sepsis origin. Crit Care 2010, 14: R219.
  • Ladakis C, Myrianthefs P, Karabinis A et al. Central venous and mixed venous oxygen saturation in critically ill patients. Respiration 2001; 68: 279-285.
  • Bethlehem C, Groenwold FM, Buter H et al. The impact of a pulmonary artery catheter based protocol on fluid and catecholamine administration in early sepsis Crit Care Res Pract 2012; 2012: 161879.
  • Robin E, Costecalde M, Lebuffe G, Vallet B. Clinical relevance of data from pulmonary artery catheter. Crit Care 2006; 10: S3.
  • Shepherd S, Pearse R. Role of central and mixed venous oxygen saturation measurement in perioperative care. Anesthesiology 2009; 111: 649-656.
  • Arnold RC, Shapiro NI, Jones AE et al. Multi-center study of early lactate clearance as a Determinant of Survival in Patients with Presumed Sepsis. Shock 2009; 32: 35-39.
  • Jones AE, Shapiro N, Trzeciak S et al. Lactate clearance versus central venous oxygen saturation as goals of early sepsis therapy. JAMA2010; 303: 739-746.
  • Cinel I, Dellinger RP. Advances in pathogenesis and management of sepsis. Curr Opin Infect Dis 2007; 20: 345-352.
  • Fuller BM, Dellinger RP. Lactate as a hemodynamic marker in the critically ill. Curr Opin Crit Care 2012; 18: 267-272.
  • Rosario AL, Park M, Brunialti MK et al. SvO2-guided resuscitation for experimental septic shock: effects of fluid infusion and dobutamine on hemodynamics, inflammatory response, and cardiovascular oxidative stres. Shock 2011; 36: 604-612.
  • Ganidagli S. Kardiyak debi ve fonksiyonlar›n›n incelenmesi. Turk Yogun Bak›m Dernegi Dergisi 2006; 4: 30-37.
  • Mozina H, Podbregar M. Near-infrared spectroscopy during stagnant ischemia estimates central venous oxygen saturation and mixed venous oxygen saturation discrepancy in patients with severe left heart failure and additional sepsis/septic shock. Crit Care 2010; 14: R42.
  • Kotake Y, Yamada T, Nagata H, Suzuki T, Takeda J. Can mixed venous haemoglobin oxygen saturation be estimated using a NICO monitor? Anesth Analg 2009; 109: 119-123.
  • Cohn SM, Nathens AB, Moore FA et al. Tissue oxygen saturation predicts the development of organ dysfunction during traumatic shock resuscitation. J Trauma 2007; 62: 44.
  • Lima A, van Bommel J, Jansen TC, Ince C, Bakker J. Low tissue oxygen saturation at the end of early goal directed therapy is associated with worse outcome in critically ill patients. Crit Care 2009; 13: S13.
  • Podbrager M, Mozina H. Skeletal muscle oxygen saturation does not estimate mixed venous oxygen saturation in patients with severe left heart failure and additional severe sepsis or septic shock. Crit Care 2007; 11: R6
APA KIR B, Bilgili B, Cinel I (2014). MİKS VENÖZ OKSİJEN SATURASYONU VE KLİNİK ÖNEMİ. , 181 - 185.
Chicago KIR Bünyamin,Bilgili Beliz,Cinel Ismail MİKS VENÖZ OKSİJEN SATURASYONU VE KLİNİK ÖNEMİ. (2014): 181 - 185.
MLA KIR Bünyamin,Bilgili Beliz,Cinel Ismail MİKS VENÖZ OKSİJEN SATURASYONU VE KLİNİK ÖNEMİ. , 2014, ss.181 - 185.
AMA KIR B,Bilgili B,Cinel I MİKS VENÖZ OKSİJEN SATURASYONU VE KLİNİK ÖNEMİ. . 2014; 181 - 185.
Vancouver KIR B,Bilgili B,Cinel I MİKS VENÖZ OKSİJEN SATURASYONU VE KLİNİK ÖNEMİ. . 2014; 181 - 185.
IEEE KIR B,Bilgili B,Cinel I "MİKS VENÖZ OKSİJEN SATURASYONU VE KLİNİK ÖNEMİ." , ss.181 - 185, 2014.
ISNAD KIR, Bünyamin vd. "MİKS VENÖZ OKSİJEN SATURASYONU VE KLİNİK ÖNEMİ". (2014), 181-185.
APA KIR B, Bilgili B, Cinel I (2014). MİKS VENÖZ OKSİJEN SATURASYONU VE KLİNİK ÖNEMİ. Anestezi Dergisi, 22(4), 181 - 185.
Chicago KIR Bünyamin,Bilgili Beliz,Cinel Ismail MİKS VENÖZ OKSİJEN SATURASYONU VE KLİNİK ÖNEMİ. Anestezi Dergisi 22, no.4 (2014): 181 - 185.
MLA KIR Bünyamin,Bilgili Beliz,Cinel Ismail MİKS VENÖZ OKSİJEN SATURASYONU VE KLİNİK ÖNEMİ. Anestezi Dergisi, vol.22, no.4, 2014, ss.181 - 185.
AMA KIR B,Bilgili B,Cinel I MİKS VENÖZ OKSİJEN SATURASYONU VE KLİNİK ÖNEMİ. Anestezi Dergisi. 2014; 22(4): 181 - 185.
Vancouver KIR B,Bilgili B,Cinel I MİKS VENÖZ OKSİJEN SATURASYONU VE KLİNİK ÖNEMİ. Anestezi Dergisi. 2014; 22(4): 181 - 185.
IEEE KIR B,Bilgili B,Cinel I "MİKS VENÖZ OKSİJEN SATURASYONU VE KLİNİK ÖNEMİ." Anestezi Dergisi, 22, ss.181 - 185, 2014.
ISNAD KIR, Bünyamin vd. "MİKS VENÖZ OKSİJEN SATURASYONU VE KLİNİK ÖNEMİ". Anestezi Dergisi 22/4 (2014), 181-185.