La Celestina: Calisto and Melibea's Tragicomedy, one of the most important works of the Spanish Literature as it deals with the conflict between the medieval society and the individual, gains importance also in the face of the Renaissance. We witness the supremacy of the norms of the society over the individual, while the writer Fernando de Rojas skillfully and delicately created the characters, focusing on the individual perception of the period. At the same time, in the work that emphasizes the point of view towards the women, universal subjects are presented to the reader by being processed with the human nature and the instincts. In the work, young Calisto -who has become a slave of his passions-, Melibea –pure, naive, faithful to the traditions-, the love lived exaggeratedly between them and the elder magician Celestina –in whom we witness extreme desires and emotions- are criticized. The work with the characters being punished as a result of their inappropriate actions that cannot be accepted by the society is thus a didactic text. In the mentioned work, the individual and the woman between the Middle Ages and the Renaissance as the subject of the text will be discussed and examined.