Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia

Ebru DEVECİ, (Department of Chemistry, Faculty of Sciences, Muğla Sıtkı Koçman University, 48000, Muğla, Turkey)
Gülsen TEL ÇAYAN, (Department of Chemistry and Chemical Processing Technologies, Muğla Vocational School, Muğla Sıtkı Koçman University, Muğla, Turkey)
Mehmet Emin DURU (Department of Chemistry, Faculty of Sciences, Muğla Sıtkı Koçman University, 48000, Muğla, Turkey)
International Journal of Secondary Metabolite
3 0
Yıl: 2018 Cilt: 5 Sayı: 3 Sayfa Aralığı: 259 - 269 Metin Dili: İngilizce DOI: 10.21448/ijsm.433681 İndeks Tarihi: 19-02-2019

Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia

Öz:
In this study, chemical composition, antioxidant, anticholinesterase andanti-urease activities of the essential oil, hexane, acetone, methanol and waterextracts of Euphorbia helioscopia were investigated. The chemical composition ofthe essential oil was analyzed by GC and GC/MS and β-cubebene (19.3 %),palmitic acid (12.2 %) and caryophyllene oxide (11.7 %) were identified as majorcompounds. The antioxidant activity of essential oil and extracts was performed byseveral methods such as β-carotene-linoleic acid, DPPH• , ABTS•+ radical scavenging, CUPRAC and metal chelating assays. The water extractshowed higher antioxidant activity than BHA and α-tocopherol in β-carotene-linoleic acid, DPPH•,ABTS•+ and CUPRAC assays with IC50: 1.08±0.39, 15.57±0.48, 1.89±0.33 and12.50±0.11 μg/mL values, respectively. Also, the anticholinesterase and antiureaseactivities were tested against acetylcholinesterase (AChE),butyrylcholinesterase (BChE) and urease enzymes, spectrophotometrically. Theacetone extract (81.23±0.58 %) showed very close BChE inhibitory activity togalantamine. The hexane extract (96.97±0.36 %) of E. helioscopia showed higheranti-urease activity than thiourea (96.93±0.17 %) whereas the essential oil(91.37±0.26 %) indicated very close anti-urease activity to the standard.
Anahtar Kelime:

Konular: Biyoloji
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA DEVECİ E, Tel-Çayan G, DURU M (2018). Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia. , 259 - 269. 10.21448/ijsm.433681
Chicago DEVECİ EBRU,Tel-Çayan Gulsen,DURU Mehmet Emin Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia. (2018): 259 - 269. 10.21448/ijsm.433681
MLA DEVECİ EBRU,Tel-Çayan Gulsen,DURU Mehmet Emin Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia. , 2018, ss.259 - 269. 10.21448/ijsm.433681
AMA DEVECİ E,Tel-Çayan G,DURU M Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia. . 2018; 259 - 269. 10.21448/ijsm.433681
Vancouver DEVECİ E,Tel-Çayan G,DURU M Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia. . 2018; 259 - 269. 10.21448/ijsm.433681
IEEE DEVECİ E,Tel-Çayan G,DURU M "Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia." , ss.259 - 269, 2018. 10.21448/ijsm.433681
ISNAD DEVECİ, EBRU vd. "Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia". (2018), 259-269. https://doi.org/10.21448/ijsm.433681
APA DEVECİ E, Tel-Çayan G, DURU M (2018). Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia. International Journal of Secondary Metabolite, 5(3), 259 - 269. 10.21448/ijsm.433681
Chicago DEVECİ EBRU,Tel-Çayan Gulsen,DURU Mehmet Emin Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia. International Journal of Secondary Metabolite 5, no.3 (2018): 259 - 269. 10.21448/ijsm.433681
MLA DEVECİ EBRU,Tel-Çayan Gulsen,DURU Mehmet Emin Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia. International Journal of Secondary Metabolite, vol.5, no.3, 2018, ss.259 - 269. 10.21448/ijsm.433681
AMA DEVECİ E,Tel-Çayan G,DURU M Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia. International Journal of Secondary Metabolite. 2018; 5(3): 259 - 269. 10.21448/ijsm.433681
Vancouver DEVECİ E,Tel-Çayan G,DURU M Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia. International Journal of Secondary Metabolite. 2018; 5(3): 259 - 269. 10.21448/ijsm.433681
IEEE DEVECİ E,Tel-Çayan G,DURU M "Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia." International Journal of Secondary Metabolite, 5, ss.259 - 269, 2018. 10.21448/ijsm.433681
ISNAD DEVECİ, EBRU vd. "Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia". International Journal of Secondary Metabolite 5/3 (2018), 259-269. https://doi.org/10.21448/ijsm.433681
Sayfa Oluşturulma Tarihi
23-04-2024 7:22

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