Hashimoto Tiroiditi Olan Hastalarda Malignensi Tesbitinde İnce İğne Aspirasyon Biyopsisinin Etkinliği
Yıl: 2017 Cilt: 7 Sayı: 1 Sayfa Aralığı: 35 - 39 Metin Dili: Türkçe DOI: 10.5505/kjms.2017.86094 İndeks Tarihi: 27-03-2019
Hashimoto Tiroiditi Olan Hastalarda Malignensi Tesbitinde İnce İğne Aspirasyon Biyopsisinin Etkinliği
Öz: Amaç: Bu çalışmanın amacı Hashimoto tiroiditli hastalarda malignitevarlığını analiz etmek ve preoperatif ince iğne aspirasyon biyopsisinin(İİAB) güvenirliliğini değerlendirmektir.Materyal ve Metot: Bu retrospektif çalışmaya Temmuz 2011 ile Aralık2014 arasında nodüler guatr nedeniyle opere edilen 66 hasta dahiledildi. Bu hastalarda preoperatif İİAB ile sitopatolojik değerlendirmeve sonrasında tiroidektomi operasyonu yapıldı. Tüm hastalara histopatolojikdeğerlendirme ile Hashimoto tiroiditi kesin tanısı koyuldu.Bulgular: İİAB sonuçları olguların 21’inde (%31,8) benign, 25’inde(%37,8) malignite için şüpheli, 13’ünde (%19,6) malign ve 7’sinde(%10,6) yetersiz olarak yorumlandı. Tiroidektomi sonrasında 14hastada (%21,2) ve 2 hastada (%3,0) sırasıyla tiroid papiller karsinomuve tiroid papiller karsinomunun folliküler varyantı saptandı.Malignite saptama açısından İİAB sonuçlarının duyarlılığı %79,özgüllüğü %39, yalancı pozitifliği %70,1, yalancı negatifliği %13,9,pozitif öngörü değeri %32,1, negatif öngörü değeri %86,0 ve tanısaldoğruluk oranı %51 olarak yorumlandı.Sonuç: Hashimoto tiroidi ile papiller tiroid karsinomunun birliktebulunması sıktır. Hashimoto tiroiditi hastalarında İİAB sonuçlarınıdeğerlendirmek çok güç olup yalancı pozitiflik oranının artmasımuhtemeldir.
Anahtar Kelime: Konular:
The Credibility of Fine-Needle Aspiration Biopsy for Malignancy in Patients with Hashimoto Diseases
Öz: Aim: This study aimed to research the presence of malignancy in patients with Hashimoto’s thyroiditis, and to examine the reliability of preoperative fine-needle aspiration biopsy (FNAB). Material and Method: This retrospective study included 66 patients who were operated on due to nodular goiter between July 2011 and December 2014. The patients underwent thyroidectomy following a cytologic analysis with FNAB. Hashimoto’s thyroiditis was testified with histopathology in all patients. Results: FNAB outcome were described as malignant in 13 (19.6%), benign in 21 (31.8%), inadequate in 7 (10.6%), and suspicion for malignancy in 25 (37.8%) cases. After thyroidectomy, existence of papillary thyroid carcinoma and follicular variant of papillary thyroid carcinoma were found in 14 (21.2%) and 2 (3.0%) patients, respectively. With regard to malignancy, FNAB displayed a specificity of 39%; sensitivity of 79%; false negative ratio of 13.9%; false positive ratio of 70.1%; positive predictive value of 32.1%; diagnostic accuracy of 51%; and negative predictive value of 86.0%. Conclusion: This coexistence of Hashimoto’s thyroiditis and papillary thyroid carcinoma is fairly mutual. FNAB outcome for such cases are difficult to score, and they are probably to rise the number of false positive cases.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | CIFTCI F, anuk t, Baran Tatar Z (2017). Hashimoto Tiroiditi Olan Hastalarda Malignensi Tesbitinde İnce İğne Aspirasyon Biyopsisinin Etkinliği. , 35 - 39. 10.5505/kjms.2017.86094 |
| Chicago | CIFTCI FATIH,anuk turgut,Baran Tatar Zeynep Hashimoto Tiroiditi Olan Hastalarda Malignensi Tesbitinde İnce İğne Aspirasyon Biyopsisinin Etkinliği. (2017): 35 - 39. 10.5505/kjms.2017.86094 |
| MLA | CIFTCI FATIH,anuk turgut,Baran Tatar Zeynep Hashimoto Tiroiditi Olan Hastalarda Malignensi Tesbitinde İnce İğne Aspirasyon Biyopsisinin Etkinliği. , 2017, ss.35 - 39. 10.5505/kjms.2017.86094 |
| AMA | CIFTCI F,anuk t,Baran Tatar Z Hashimoto Tiroiditi Olan Hastalarda Malignensi Tesbitinde İnce İğne Aspirasyon Biyopsisinin Etkinliği. . 2017; 35 - 39. 10.5505/kjms.2017.86094 |
| Vancouver | CIFTCI F,anuk t,Baran Tatar Z Hashimoto Tiroiditi Olan Hastalarda Malignensi Tesbitinde İnce İğne Aspirasyon Biyopsisinin Etkinliği. . 2017; 35 - 39. 10.5505/kjms.2017.86094 |
| IEEE | CIFTCI F,anuk t,Baran Tatar Z "Hashimoto Tiroiditi Olan Hastalarda Malignensi Tesbitinde İnce İğne Aspirasyon Biyopsisinin Etkinliği." , ss.35 - 39, 2017. 10.5505/kjms.2017.86094 |
| ISNAD | CIFTCI, FATIH vd. "Hashimoto Tiroiditi Olan Hastalarda Malignensi Tesbitinde İnce İğne Aspirasyon Biyopsisinin Etkinliği". (2017), 35-39. https://doi.org/10.5505/kjms.2017.86094 |
| APA | CIFTCI F, anuk t, Baran Tatar Z (2017). Hashimoto Tiroiditi Olan Hastalarda Malignensi Tesbitinde İnce İğne Aspirasyon Biyopsisinin Etkinliği. Kafkas Tıp Bilimleri Dergisi, 7(1), 35 - 39. 10.5505/kjms.2017.86094 |
| Chicago | CIFTCI FATIH,anuk turgut,Baran Tatar Zeynep Hashimoto Tiroiditi Olan Hastalarda Malignensi Tesbitinde İnce İğne Aspirasyon Biyopsisinin Etkinliği. Kafkas Tıp Bilimleri Dergisi 7, no.1 (2017): 35 - 39. 10.5505/kjms.2017.86094 |
| MLA | CIFTCI FATIH,anuk turgut,Baran Tatar Zeynep Hashimoto Tiroiditi Olan Hastalarda Malignensi Tesbitinde İnce İğne Aspirasyon Biyopsisinin Etkinliği. Kafkas Tıp Bilimleri Dergisi, vol.7, no.1, 2017, ss.35 - 39. 10.5505/kjms.2017.86094 |
| AMA | CIFTCI F,anuk t,Baran Tatar Z Hashimoto Tiroiditi Olan Hastalarda Malignensi Tesbitinde İnce İğne Aspirasyon Biyopsisinin Etkinliği. Kafkas Tıp Bilimleri Dergisi. 2017; 7(1): 35 - 39. 10.5505/kjms.2017.86094 |
| Vancouver | CIFTCI F,anuk t,Baran Tatar Z Hashimoto Tiroiditi Olan Hastalarda Malignensi Tesbitinde İnce İğne Aspirasyon Biyopsisinin Etkinliği. Kafkas Tıp Bilimleri Dergisi. 2017; 7(1): 35 - 39. 10.5505/kjms.2017.86094 |
| IEEE | CIFTCI F,anuk t,Baran Tatar Z "Hashimoto Tiroiditi Olan Hastalarda Malignensi Tesbitinde İnce İğne Aspirasyon Biyopsisinin Etkinliği." Kafkas Tıp Bilimleri Dergisi, 7, ss.35 - 39, 2017. 10.5505/kjms.2017.86094 |
| ISNAD | CIFTCI, FATIH vd. "Hashimoto Tiroiditi Olan Hastalarda Malignensi Tesbitinde İnce İğne Aspirasyon Biyopsisinin Etkinliği". Kafkas Tıp Bilimleri Dergisi 7/1 (2017), 35-39. https://doi.org/10.5505/kjms.2017.86094 |
