TY  - JOUR
TI  - Impact of Pulmonary Embolism on Acute Chronic Obstructive Pulmonary Disease Exacerbation
AB  - Purpose: This study aims to assess effect of pulmonary embolism (PE) onclinical and laboratory parameters of patients hospitalized for acuteexacerbations of chronic obstructive pulmonary disease (AECOPD). Riskfactors for PE development were also evaluated.Methods: In this retrospective study, patients who were hospitalized forAECOPD and underwent computed tomographic pulmonary angiography scan(CTPA) between 2009 and 2011 were included. Patients with PE wereevaluated separately as those diagnosed at initial examination and thosesuspected during exacerbation therapy since they had inadequate response.Binary logistic regression analysis was used in order to determine risk factorson PE development.Results: The study consisted of 36 patients, 13 patients (36.1%) had PE. FEV1and FEV1/FVC values were higher in PE group (53.7% vs 41.4%; 62.3% vs 52%respectively; p<0.05). There was no difference between D-dimer levels of PEand non-PE patients. Risk of PE development did not differ with analyzedvariables. Those diagnosed at initial examination had significantly less numberof exacerbations in the last one year than those diagnosed during therapy (1.1vs 3.2; p<0.05).Conclusion: PE should always be considered in AECOPD etiology, particularlyin patients with frequent exacerbation history and D-dimer levels may bemisleading.
AU  - Türk, Murat
AU  - Yıldırım, Fatma
AU  - Kokturk, Nurdan
AU  - sevimli, nurgül
DO  - 10.12996/gmj.2017.51
PY  - 2017
JO  - Gazi Medical Journal
VL  - 28
IS  - 3
SN  - 1300-056X
SP  - 168
EP  - 170
DB  - TRDizin
UR  - http://search/yayin/detay/294851
ER  -