The effectiveness of pedicle screw immersion in vancomycin and ceftriaxone solution for the prevention of postoperative spinal infection: A prospective comparative study
Yıl: 2018 Cilt: 52 Sayı: 4 Sayfa Aralığı: 289 - 293 Metin Dili: İngilizce DOI: 10.1016/j.aott.2018.05.004 İndeks Tarihi: 18-04-2019
The effectiveness of pedicle screw immersion in vancomycin and ceftriaxone solution for the prevention of postoperative spinal infection: A prospective comparative study
Öz: Objective: The aim of this study was to evaluate the efficacy of the local application of vancomycinhydrochloride (HCl)eceftriaxone disodium hemiheptahydrate onto implants before using them to preventpostoperative infection.Methods: The study included 239 patients (153 women and 86 men; mean age: 48.23 ± 16.77 years) whohad thoracolumbar stabilization with transpedicular screws. All surgeries were performed by the samesurgeon. Patients were divided into two groups. In the group 1 (n ¼ 104), implants were bathed in a solutionof local prophylactic antibiotics for 5 seconds just before implantation. In the group 2 (n ¼ 135),implants were not bathed before implantation. Local antibiotics used in the study was effective againstgram positive bacteria (including methicillin resistant Staphylococcus aureus) and gram negative bacteria.The rate of surgical site infection and wound healing time were compared between the groups.Results: A total of 10 patients (4.1%) had deep wound infection and 20 (8.4%) had superficial infection.The most common bacteria was Staphylococcus aureus. One patient died 21 days after the surgerybecause of sepsis. The wound healed in a mean of 9.66 ± 2.04 days in patients who had no infection andin 32.33 ± 19.64 days in patients with infection (p < 0.001). The patients in group 1 had significantly lessdeep infection than the patients in group 2 (p < 0.05). However, there was no statistically significantdifference between the groups for superficial infection. Patients with vertebral fracture had significantlylower deep infection rate in group 1. The deep infection rate of group 1 patients with diabetes, withbleeding of more than 2000 mL, transfused with blood transfusions above 3 units and with dural injurywas significantly lower than those in the group 2. None of the patients had allergic reactions to the drugsused for local prophylaxis.Conclusions: This study shown that bathing implants in antibiotics solution was an effective localprophylactic method to prevent deep infections in spinal surgeries with instrumentation.
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Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Bibliyografik
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| APA | eren b, KARAGÖZ GÜZEY F, KITIS S, ÖZKAN N, KORKUT C (2018). The effectiveness of pedicle screw immersion in vancomycin and ceftriaxone solution for the prevention of postoperative spinal infection: A prospective comparative study. , 289 - 293. 10.1016/j.aott.2018.05.004 |
| Chicago | eren burak,KARAGÖZ GÜZEY FEYZA,KITIS Serkan,ÖZKAN Nezih,KORKUT Cafer The effectiveness of pedicle screw immersion in vancomycin and ceftriaxone solution for the prevention of postoperative spinal infection: A prospective comparative study. (2018): 289 - 293. 10.1016/j.aott.2018.05.004 |
| MLA | eren burak,KARAGÖZ GÜZEY FEYZA,KITIS Serkan,ÖZKAN Nezih,KORKUT Cafer The effectiveness of pedicle screw immersion in vancomycin and ceftriaxone solution for the prevention of postoperative spinal infection: A prospective comparative study. , 2018, ss.289 - 293. 10.1016/j.aott.2018.05.004 |
| AMA | eren b,KARAGÖZ GÜZEY F,KITIS S,ÖZKAN N,KORKUT C The effectiveness of pedicle screw immersion in vancomycin and ceftriaxone solution for the prevention of postoperative spinal infection: A prospective comparative study. . 2018; 289 - 293. 10.1016/j.aott.2018.05.004 |
| Vancouver | eren b,KARAGÖZ GÜZEY F,KITIS S,ÖZKAN N,KORKUT C The effectiveness of pedicle screw immersion in vancomycin and ceftriaxone solution for the prevention of postoperative spinal infection: A prospective comparative study. . 2018; 289 - 293. 10.1016/j.aott.2018.05.004 |
| IEEE | eren b,KARAGÖZ GÜZEY F,KITIS S,ÖZKAN N,KORKUT C "The effectiveness of pedicle screw immersion in vancomycin and ceftriaxone solution for the prevention of postoperative spinal infection: A prospective comparative study." , ss.289 - 293, 2018. 10.1016/j.aott.2018.05.004 |
| ISNAD | eren, burak vd. "The effectiveness of pedicle screw immersion in vancomycin and ceftriaxone solution for the prevention of postoperative spinal infection: A prospective comparative study". (2018), 289-293. https://doi.org/10.1016/j.aott.2018.05.004 |
| APA | eren b, KARAGÖZ GÜZEY F, KITIS S, ÖZKAN N, KORKUT C (2018). The effectiveness of pedicle screw immersion in vancomycin and ceftriaxone solution for the prevention of postoperative spinal infection: A prospective comparative study. Acta Orthopaedica et Traumatologica Turcica, 52(4), 289 - 293. 10.1016/j.aott.2018.05.004 |
| Chicago | eren burak,KARAGÖZ GÜZEY FEYZA,KITIS Serkan,ÖZKAN Nezih,KORKUT Cafer The effectiveness of pedicle screw immersion in vancomycin and ceftriaxone solution for the prevention of postoperative spinal infection: A prospective comparative study. Acta Orthopaedica et Traumatologica Turcica 52, no.4 (2018): 289 - 293. 10.1016/j.aott.2018.05.004 |
| MLA | eren burak,KARAGÖZ GÜZEY FEYZA,KITIS Serkan,ÖZKAN Nezih,KORKUT Cafer The effectiveness of pedicle screw immersion in vancomycin and ceftriaxone solution for the prevention of postoperative spinal infection: A prospective comparative study. Acta Orthopaedica et Traumatologica Turcica, vol.52, no.4, 2018, ss.289 - 293. 10.1016/j.aott.2018.05.004 |
| AMA | eren b,KARAGÖZ GÜZEY F,KITIS S,ÖZKAN N,KORKUT C The effectiveness of pedicle screw immersion in vancomycin and ceftriaxone solution for the prevention of postoperative spinal infection: A prospective comparative study. Acta Orthopaedica et Traumatologica Turcica. 2018; 52(4): 289 - 293. 10.1016/j.aott.2018.05.004 |
| Vancouver | eren b,KARAGÖZ GÜZEY F,KITIS S,ÖZKAN N,KORKUT C The effectiveness of pedicle screw immersion in vancomycin and ceftriaxone solution for the prevention of postoperative spinal infection: A prospective comparative study. Acta Orthopaedica et Traumatologica Turcica. 2018; 52(4): 289 - 293. 10.1016/j.aott.2018.05.004 |
| IEEE | eren b,KARAGÖZ GÜZEY F,KITIS S,ÖZKAN N,KORKUT C "The effectiveness of pedicle screw immersion in vancomycin and ceftriaxone solution for the prevention of postoperative spinal infection: A prospective comparative study." Acta Orthopaedica et Traumatologica Turcica, 52, ss.289 - 293, 2018. 10.1016/j.aott.2018.05.004 |
| ISNAD | eren, burak vd. "The effectiveness of pedicle screw immersion in vancomycin and ceftriaxone solution for the prevention of postoperative spinal infection: A prospective comparative study". Acta Orthopaedica et Traumatologica Turcica 52/4 (2018), 289-293. https://doi.org/10.1016/j.aott.2018.05.004 |
