Placenta, Secret Witness of Infant Morbidities: The Relationship Between Placental Histology and Outcome of the Premature Infant

Okulu, Emel; YILDIZ, DURAN; Kahvecioğlu, Dilek; ERDEVE, OMER; ALAN, Serdar; ARSAN, Saadet; ATASAY, FATMA BEGÜM; CAKIR, Ufuk; OKCU HEPER, Aylin

doi:10.5146/tjpath.2018.01443

Placenta, Secret Witness of Infant Morbidities: The Relationship Between Placental Histology and Outcome of the Premature Infant

Ufuk CAKIR, (Ankara Üniversitesi, Tıp Fakültesi, Neonatoloji Bölümü, Ankara, Türkiye)

Duran YILDIZ, (Ankara Üniversitesi, Tıp Fakültesi, Neonatoloji Bölümü, Ankara, Türkiye)

Dilek KAHVECİOĞLU, (Ankara Üniversitesi, Tıp Fakültesi, Neonatoloji Bölümü, Ankara, Türkiye)

Emel OKULU, (Ankara Üniversitesi, Tıp Fakültesi, Neonatoloji Bölümü, Ankara, Türkiye)

Serdar ALAN, (Ankara Üniversitesi, Tıp Fakültesi, Neonatoloji Bölümü, Ankara, Türkiye)

Ömer ERDEVE, (Ankara Üniversitesi, Tıp Fakültesi, Neonatoloji Bölümü, Ankara, Türkiye)

Aylin OKCU HEPER, (Ankara Üniversitesi, Tıp Fakültesi, Patoloji Bölümü, Ankara, Türkiye)

FATMA BEGÜM ATASAY, (Ankara Üniversitesi, Tıp Fakültesi, Neonatoloji Bölümü, Ankara, Türkiye)

Saadet ARSAN (Ankara Üniversitesi, Tıp Fakültesi, Neonatoloji Bölümü, Ankara, Türkiye)

Türk Patoloji Dergisi

3 1

Yıl: 2019 Cilt: 35 Sayı: 1 Sayfa Aralığı: 28 - 35 Metin Dili: İngilizce DOI: 10.5146/tjpath.2018.01443 İndeks Tarihi: 06-05-2019

Placenta, Secret Witness of Infant Morbidities: The Relationship Between Placental Histology and Outcome of the Premature Infant

Öz:

Objective: The microscopic and macroscopic features of the placenta can contribute to the clinical understanding of premature delivery. The aim of our study was to figure out the relationship between the histopathological findings of the placentas of premature deliveries and its effects on neonatal morbidity and mortality. Material and Method: The placentas of 284 singleton preterm infants with <35 weeks of gestation were examined. Three groups were created as the normal, chorioamnionitis and vasculopathy groups according to the histopathological findings in the placentas of the subjects. Results: The mean gestational age of the infants in the study group was 30.5 ± 3.2 weeks, and the mean birth weight was 1588 ± 581 g. The pathology was normal in ninety-six (33.8%), vasculopathy in 153 (53.9%) and chorioamnionitis in 35 (12.3%). The gestation age of the infants was lower in the chorioamnionitis group. Moreover, retinopathy of prematurity, early onset neonatal sepsis, and duration of respiratory support were found to be higher in the chorioamnionitis group. In the vasculopathy group, preeclampsia and small for gestational age were found to be significantly higher. Conclusion: Histopathological findings of the placentas from preterm deliveries provided important data in determining the etiology of preterm delivery and outcomes of infants. Infants delivered by mothers with chorioamnionitis were particularly found to be more preterm, and these preterm infants would have a longer hospital stay, higher respiratory support requirement, and more serious morbidities.

Anahtar Kelime: Chorioamnionitis Neonatal morbidity Placental pathology Prematurity Vasculopathy

Konular: Patoloji Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	CAKIR U, YILDIZ D, Kahvecioğlu D, Okulu E, ALAN S, ERDEVE O, OKCU HEPER A, ATASAY F, ARSAN S (2019). Placenta, Secret Witness of Infant Morbidities: The Relationship Between Placental Histology and Outcome of the Premature Infant. , 28 - 35. 10.5146/tjpath.2018.01443
Chicago	CAKIR Ufuk,YILDIZ DURAN,Kahvecioğlu Dilek,Okulu Emel,ALAN Serdar,ERDEVE OMER,OKCU HEPER Aylin,ATASAY FATMA BEGÜM,ARSAN Saadet Placenta, Secret Witness of Infant Morbidities: The Relationship Between Placental Histology and Outcome of the Premature Infant. (2019): 28 - 35. 10.5146/tjpath.2018.01443
MLA	CAKIR Ufuk,YILDIZ DURAN,Kahvecioğlu Dilek,Okulu Emel,ALAN Serdar,ERDEVE OMER,OKCU HEPER Aylin,ATASAY FATMA BEGÜM,ARSAN Saadet Placenta, Secret Witness of Infant Morbidities: The Relationship Between Placental Histology and Outcome of the Premature Infant. , 2019, ss.28 - 35. 10.5146/tjpath.2018.01443
AMA	CAKIR U,YILDIZ D,Kahvecioğlu D,Okulu E,ALAN S,ERDEVE O,OKCU HEPER A,ATASAY F,ARSAN S Placenta, Secret Witness of Infant Morbidities: The Relationship Between Placental Histology and Outcome of the Premature Infant. . 2019; 28 - 35. 10.5146/tjpath.2018.01443
Vancouver	CAKIR U,YILDIZ D,Kahvecioğlu D,Okulu E,ALAN S,ERDEVE O,OKCU HEPER A,ATASAY F,ARSAN S Placenta, Secret Witness of Infant Morbidities: The Relationship Between Placental Histology and Outcome of the Premature Infant. . 2019; 28 - 35. 10.5146/tjpath.2018.01443
IEEE	CAKIR U,YILDIZ D,Kahvecioğlu D,Okulu E,ALAN S,ERDEVE O,OKCU HEPER A,ATASAY F,ARSAN S "Placenta, Secret Witness of Infant Morbidities: The Relationship Between Placental Histology and Outcome of the Premature Infant." , ss.28 - 35, 2019. 10.5146/tjpath.2018.01443
ISNAD	CAKIR, Ufuk vd. "Placenta, Secret Witness of Infant Morbidities: The Relationship Between Placental Histology and Outcome of the Premature Infant". (2019), 28-35. https://doi.org/10.5146/tjpath.2018.01443

APA	CAKIR U, YILDIZ D, Kahvecioğlu D, Okulu E, ALAN S, ERDEVE O, OKCU HEPER A, ATASAY F, ARSAN S (2019). Placenta, Secret Witness of Infant Morbidities: The Relationship Between Placental Histology and Outcome of the Premature Infant. Türk Patoloji Dergisi, 35(1), 28 - 35. 10.5146/tjpath.2018.01443
Chicago	CAKIR Ufuk,YILDIZ DURAN,Kahvecioğlu Dilek,Okulu Emel,ALAN Serdar,ERDEVE OMER,OKCU HEPER Aylin,ATASAY FATMA BEGÜM,ARSAN Saadet Placenta, Secret Witness of Infant Morbidities: The Relationship Between Placental Histology and Outcome of the Premature Infant. Türk Patoloji Dergisi 35, no.1 (2019): 28 - 35. 10.5146/tjpath.2018.01443
MLA	CAKIR Ufuk,YILDIZ DURAN,Kahvecioğlu Dilek,Okulu Emel,ALAN Serdar,ERDEVE OMER,OKCU HEPER Aylin,ATASAY FATMA BEGÜM,ARSAN Saadet Placenta, Secret Witness of Infant Morbidities: The Relationship Between Placental Histology and Outcome of the Premature Infant. Türk Patoloji Dergisi, vol.35, no.1, 2019, ss.28 - 35. 10.5146/tjpath.2018.01443
AMA	CAKIR U,YILDIZ D,Kahvecioğlu D,Okulu E,ALAN S,ERDEVE O,OKCU HEPER A,ATASAY F,ARSAN S Placenta, Secret Witness of Infant Morbidities: The Relationship Between Placental Histology and Outcome of the Premature Infant. Türk Patoloji Dergisi. 2019; 35(1): 28 - 35. 10.5146/tjpath.2018.01443
Vancouver	CAKIR U,YILDIZ D,Kahvecioğlu D,Okulu E,ALAN S,ERDEVE O,OKCU HEPER A,ATASAY F,ARSAN S Placenta, Secret Witness of Infant Morbidities: The Relationship Between Placental Histology and Outcome of the Premature Infant. Türk Patoloji Dergisi. 2019; 35(1): 28 - 35. 10.5146/tjpath.2018.01443
IEEE	CAKIR U,YILDIZ D,Kahvecioğlu D,Okulu E,ALAN S,ERDEVE O,OKCU HEPER A,ATASAY F,ARSAN S "Placenta, Secret Witness of Infant Morbidities: The Relationship Between Placental Histology and Outcome of the Premature Infant." Türk Patoloji Dergisi, 35, ss.28 - 35, 2019. 10.5146/tjpath.2018.01443
ISNAD	CAKIR, Ufuk vd. "Placenta, Secret Witness of Infant Morbidities: The Relationship Between Placental Histology and Outcome of the Premature Infant". Türk Patoloji Dergisi 35/1 (2019), 28-35. https://doi.org/10.5146/tjpath.2018.01443