The aim of the treatment of cancer is to destroy cancer cells and pre- vent the growth and development of cancer cells. However, during the treatment period, healthy cells in addition to cancer cells cau- se the destruction. For example, the rapid division of the epithelial cells of the oral mucosa by blocking the growth of the secretion of the oral mucosa flora causes. When the oral mucosa is damaged, the cells of the oral epithelium are weakened, edema, erythema, ble- eding and ulcerations occur. Chemotherapy is a cancer treatment that uses drugs to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. These effects due to oral mucositis may negatively affect the patient, reducing the dose of the treatment taken by the patient, or skipping the dose. For this reason, the management of oral mucositis seen in cancer patients receiving chemotherapy is important for patients. Effective management of oral mucositis can be done by continuing nursing care during cancer treatment. Care practices for the management of oral mucositis of Oncology nurses should be aware that the current and evidence-ba- sed practices. The study was carried out to explain the current and evidence-based practices applied in oral mucositis management.