The Availability of Echinococcus IgG ELISA for Diagnosing Pulmonary Hydatid Cysts
Yıl: 2018 Cilt: 50 Sayı: 3 Sayfa Aralığı: 144 - 147 Metin Dili: İngilizce DOI: 10.5152/eurasianjmed.2018.16104 İndeks Tarihi: 12-06-2019
The Availability of Echinococcus IgG ELISA for Diagnosing Pulmonary Hydatid Cysts
Öz: Objective: In this study, we researched the availability of Echinococcus IgG ELISA in pulmonary hydatid cysts.Materials and Methods: Between January 2008 and December 2015, 93 successive cases, which were stud- ied in preoperative Echinococcus IgG and histopathologically found to have pulmonary hydatid cysts, were retrospectively analyzed. Age and sex of the cases and the cyst’s location, number, size, spread to other organs outside the lungs, and its condition as intact or ruptured were reviewed.Results: Forty-seven (50.5%) patients were male and 46 (49.5%) patients were female; the mean age was 27.7±19.6 years. While in 56 (60.2%) cases, only lung cysts were detected, 32 (34.4%) cases presented with both lung and liver cysts. While lung cysts were single in 71 (76.3%), they were multiple in 22 (23.6%) cases (between 2 and 20 pieces). In 48 (51.6%) cases, cysts were in the right lung, and in 32 (34.4%) cases, they were in the left. In 13 (14%) cases, cysts presented in both the right and left lungs. The mean diameter of the pulmonary cysts was 6.4 cm (ranging from 2 to 19 cm). In 53 (57%) cases, hydatid cysts were ruptured, whereas in 40 (43%) cases, the cysts were intact. While general Echinococcus IgG was found to be positive in 53 (57%) cases, it was negative in 40 (43%) cases. There were 53 ruptured cases, and 48 (90.6%) of them were test-positive; however, the test was positive in only 5 (12.5%) out of the 40 cases where the cysts were intact (p<0.001). A statistically significant correlation has not been found between IgG and patient age, gen- der, cyst location, number of cysts, cyst diameter, and extrapulmonary involvement.Conclusion: Our study demonstrated that the most important factor that affects the positivity of Echinococ- cus IgG is the rupture of cysts. When ruptured cysts become confusing, Echinococcus IgG can contribute toward a diagnosis.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
- Aydin Y, Dostbil A, Araz O, et al. Pre-school chil- dren with hydatid lung disease. Acta Chir Belg 2013; 113: 340-5. [CrossRef]
- Eris FN, Akisu C, Aksoy U. Evaluation of two
- ELISA and two indirect hemagglutination tests for serodiagnosis of pulmonary hydatid disease. Korean J Parasitol 2009; 47: 427-9. [CrossRef]
- Beyhan YE, Babür C, Mungan M, Taylan Özkan A. Evaluation of cystic echinococcosis suspected patients applied to national parasitology refer- ence laboratory of public health institution of Turkey between 2009-2013. Turkiye Parazitol Derg 2015; 39: 17-21. [CrossRef]
- Engvall E, Perlmann P. Enzyme-linked immu-nosorbent assay (ELISA). Quantitative assay of immunoglobulin G. Immunochemistry 1971; 8: 871-4. [CrossRef]
- Karadağ A, Yanık K, Ünal N, Odabaşı H, Hökelek Evaluation of materials sent due to suspected cystic echinococcosis to the parasitology labo- ratory of Ondokuz Mayıs University Medical School between the Years 2005-2011. Turkiye Parazitol Derg 2013; 37: 28-31. [CrossRef]
- Siracusano A, Buttari B, Delunardo F, et al. Critical points in the immunodiagnosis of cystic echi- nococcosis in humans. Parassitologia 2004; 46:401-3.
- Eşgin M, Aktaş M, Coşkun S. The investigation of antibody presence in the sera of patients with a suspicion of cystic echinococcosis by using indi- rect hemaglutination test (IHA). Turkiye Parazi- tol Derg 2007; 31: 283-7.
- Wuestenberg J, Gruener B, Oeztuerk S, et al. Di- agnostics in cystic echinococcosis: serology ver- sus ultrasonography. Turk J Gastroenterol 2014; 25: 398-404. [CrossRef]
- Erdem CZ, Erdem LO. Radiological character- istics of pulmonary hydatid disease in children: Less common radiological appearances. Eur J Radiol 2003; 45: 123-8. [CrossRef]
- Long NM, Smith CS. Causes and imaging fea-tures of false positives and false negatives on F-PET/CT in oncologic imaging. Insights Imaging 2011; 6: 679-98. [CrossRef]
- Lightowlers MW, Gottstein B. Echinococcosis/ hydatidosis: antigens, immunological and mo- lecular diagnosis. In: Thompson RCA, Lymbery AJ, editors. Echinococcus and hydatid disease. Wallingford, UK: CAB International; 1995. p. 355-410.
- Ben Nouir N, Nuñez S, Gianinazzi C, et al. As- sessment of Echinococcus granulosus somatic protoscolex antigens for serological follow-up of young patients surgically treated for cystic echi- nococcosis. J Clin Microbiol 2008; 46: 1631-40. [CrossRef]
- Okuş A, Sevinç B, Ay S, Karahan Ö, Eryılmaz MA, Er C. Relation between serology and grow-up time in atypically localized hydatic cysts. Turkiye Parazitol Derg 2013; 37: 257-61. [CrossRef]
- Babba H, Messedi A, Masmoudi S, et al. Diagno- sis of human hydatidosis: Comparison between imagery and six serologic techniques. Am J Trop Med Hyg 1994; 50: 64-68. [CrossRef]
- Aydın M, Adıyaman G, Doğruman-Al F, Kuştimur S, Ozkan S. Determination of anti-echinococcus IgG antibodies by ELISA in patients with suspect- ed hydatid cyst. Turkiye Parazitol Derg 2012; 36: 61-4. [CrossRef]
- Chan SY, De Bruyne LA, Goodman RE, et al. In vivo depletion of CD8+ T cells results in Th2 cytokine production and alternate mechanisms of allograft rejection. Transplantation 1995; 59: 1155-61. [CrossRef]
APA | Aydin Y, ALTUNTAŞ B, Kaya A, ULAŞ A, UYANIK M, EROĞLU A (2018). The Availability of Echinococcus IgG ELISA for Diagnosing Pulmonary Hydatid Cysts. , 144 - 147. 10.5152/eurasianjmed.2018.16104 |
Chicago | Aydin Yener,ALTUNTAŞ Bayram,Kaya Abdulkadir,ULAŞ ALİ BİLAL,UYANIK Muhammet Hamidullah,EROĞLU ATİLA The Availability of Echinococcus IgG ELISA for Diagnosing Pulmonary Hydatid Cysts. (2018): 144 - 147. 10.5152/eurasianjmed.2018.16104 |
MLA | Aydin Yener,ALTUNTAŞ Bayram,Kaya Abdulkadir,ULAŞ ALİ BİLAL,UYANIK Muhammet Hamidullah,EROĞLU ATİLA The Availability of Echinococcus IgG ELISA for Diagnosing Pulmonary Hydatid Cysts. , 2018, ss.144 - 147. 10.5152/eurasianjmed.2018.16104 |
AMA | Aydin Y,ALTUNTAŞ B,Kaya A,ULAŞ A,UYANIK M,EROĞLU A The Availability of Echinococcus IgG ELISA for Diagnosing Pulmonary Hydatid Cysts. . 2018; 144 - 147. 10.5152/eurasianjmed.2018.16104 |
Vancouver | Aydin Y,ALTUNTAŞ B,Kaya A,ULAŞ A,UYANIK M,EROĞLU A The Availability of Echinococcus IgG ELISA for Diagnosing Pulmonary Hydatid Cysts. . 2018; 144 - 147. 10.5152/eurasianjmed.2018.16104 |
IEEE | Aydin Y,ALTUNTAŞ B,Kaya A,ULAŞ A,UYANIK M,EROĞLU A "The Availability of Echinococcus IgG ELISA for Diagnosing Pulmonary Hydatid Cysts." , ss.144 - 147, 2018. 10.5152/eurasianjmed.2018.16104 |
ISNAD | Aydin, Yener vd. "The Availability of Echinococcus IgG ELISA for Diagnosing Pulmonary Hydatid Cysts". (2018), 144-147. https://doi.org/10.5152/eurasianjmed.2018.16104 |
APA | Aydin Y, ALTUNTAŞ B, Kaya A, ULAŞ A, UYANIK M, EROĞLU A (2018). The Availability of Echinococcus IgG ELISA for Diagnosing Pulmonary Hydatid Cysts. Eurasian Journal of Medicine, 50(3), 144 - 147. 10.5152/eurasianjmed.2018.16104 |
Chicago | Aydin Yener,ALTUNTAŞ Bayram,Kaya Abdulkadir,ULAŞ ALİ BİLAL,UYANIK Muhammet Hamidullah,EROĞLU ATİLA The Availability of Echinococcus IgG ELISA for Diagnosing Pulmonary Hydatid Cysts. Eurasian Journal of Medicine 50, no.3 (2018): 144 - 147. 10.5152/eurasianjmed.2018.16104 |
MLA | Aydin Yener,ALTUNTAŞ Bayram,Kaya Abdulkadir,ULAŞ ALİ BİLAL,UYANIK Muhammet Hamidullah,EROĞLU ATİLA The Availability of Echinococcus IgG ELISA for Diagnosing Pulmonary Hydatid Cysts. Eurasian Journal of Medicine, vol.50, no.3, 2018, ss.144 - 147. 10.5152/eurasianjmed.2018.16104 |
AMA | Aydin Y,ALTUNTAŞ B,Kaya A,ULAŞ A,UYANIK M,EROĞLU A The Availability of Echinococcus IgG ELISA for Diagnosing Pulmonary Hydatid Cysts. Eurasian Journal of Medicine. 2018; 50(3): 144 - 147. 10.5152/eurasianjmed.2018.16104 |
Vancouver | Aydin Y,ALTUNTAŞ B,Kaya A,ULAŞ A,UYANIK M,EROĞLU A The Availability of Echinococcus IgG ELISA for Diagnosing Pulmonary Hydatid Cysts. Eurasian Journal of Medicine. 2018; 50(3): 144 - 147. 10.5152/eurasianjmed.2018.16104 |
IEEE | Aydin Y,ALTUNTAŞ B,Kaya A,ULAŞ A,UYANIK M,EROĞLU A "The Availability of Echinococcus IgG ELISA for Diagnosing Pulmonary Hydatid Cysts." Eurasian Journal of Medicine, 50, ss.144 - 147, 2018. 10.5152/eurasianjmed.2018.16104 |
ISNAD | Aydin, Yener vd. "The Availability of Echinococcus IgG ELISA for Diagnosing Pulmonary Hydatid Cysts". Eurasian Journal of Medicine 50/3 (2018), 144-147. https://doi.org/10.5152/eurasianjmed.2018.16104 |