TY  - JOUR
TI  - Can serum mean platelet volume be used as an inflammatory marker in patients with celiac disease?
AB  - Background and Aims: Mean platelet volume has been studied asa simple inflammatory marker in several diseases. Some studies havereported that mean platelet volume increases in myocardial infarctionand cerebrovascular disease. Contrarily, it decreases in rheumatoidarthritis, ankylosing spondylitis, and inflammatory bowel disease. Theaim of this study was to evaluate whether mean platelet volume waschanged in celiac disease and whether it could be used to monitor agluten-free diet in patients. Materials and Methods: After excludingpatients with severe comorbidities and patients who did not complywith the gluten-free diet, a total of 50 patients with celiac disease(men/women: 9/41) and 50 healthy subjects (men/women: 10/40)were included in the study. The diagnosis of celiac disease was basedon standard serological, endoscopic, and histological criteria. The studyenrolled patients with celiac disease who recovered clinically and serologically1 year after gluten-free diet. Complete blood count analyseswere performed within 2 h after collection with the use of the Beckmancoulter analyzer. Results: Mean platelet volume levels were not significantlydifferent in the celiac disease group than that of in the controlgroup. In the celiac disease group, the mean platelet volume levels didnot change after 1 year of gluten-free diet compared with the timeof celiac disease diagnosis. On the contrary, a decrease in the plateletcount after gluten-free diet was detected. Conclusion: This studydemonstrates that mean platelet volume is not altered in patients withceliac disease, and it also showed that mean platelet volume cannotbe used as a marker for predicting dietary compliance in patients withceliac disease.
AU  - akın, fatma ebru
AU  - Köseoğlu, Hüseyin
AU  - TAYFUR YÜREKLİ, ÖYKÜ
AU  - TAHTACI, Mustafa
AU  - ERSOY, Osman
AU  - Başaran, Murat
AU  - DEMİREZER BOLAT, Aylin
DO  - 10.17941/agd.457178
PY  - 2018
JO  - Akademik Gastroenteroloji Dergisi
VL  - 17
IS  - 2
SN  - 1303-6629
SP  - 62
EP  - 65
DB  - TRDizin
UR  - http://search/yayin/detay/298723
ER  -