The Effect of Ketogenic Diet Treatment in Drug-resistant Epilepsies of Childhood

Gizem ÖZATA UYAR, (Gazi University, Faculty of Health Sciences, Department of Nutrition and Dietetics, Ankara, Turkey)
Nevin ŞANLIER (Gazi University, Faculty of Health Sciences, Department of Nutrition and Dietetics, Ankara, Turkey)
Türk Nöroloji Dergisi
1 1
Yıl: 2018 Cilt: 24 Sayı: 3 Sayfa Aralığı: 216 - 225 Metin Dili: İngilizce İndeks Tarihi: 14-06-2019

The Effect of Ketogenic Diet Treatment in Drug-resistant Epilepsies of Childhood

Öz:
Epilepsy is an important health issue. The interest in ketogenic diet (KD) treatment in children and adolescents with drug-resistant epilepsy has increased in recent years. It was thought that KD was a last option of treatment in patients who were unresponsive to 2 or 3 anticonvulsant drugs. KD with limited protein, low carbohydrate, and high fat content was thought as a last option of treatment, previously. However, nowadays it is the most selected therapy worldwide in epileptic children and adolescents. Ketone bodies are elevated in the blood due to low carbohydrate and high lipid content of KD. Through the elevation of ketone bodies, the brain uses ketone bodies as energy sources, which results in decreased in epileptic seizures. Medical nutritional therapy during treatment of childhood epilepsies should also provide normal growth and development. For this reason, full compliance with the diet is important. The effect, place, and importance of ketogenic nutrition therapy in drug-resistant epilepsies of childhood are discussed in this review.
Anahtar Kelime:

Konular: Nörolojik Bilimler

Çocukluk Çağı Dirençli Epilepsilerinde Ketojenik Diyet Uygulamalarının Etkisi

Öz:
Epilepsi önemli bir sağlık sorunudur. Son yıllarda dirençli epileptik çocuk ve adölesanlarda ketojenik diyet (KD) uygulamalarına olan ilgi giderek artmaktadır. KD 2-3 çeşit antikonvülzan ilaçla nöbet kontrolü sağlanamadığı durumlarda son çare tedavi yöntemi olarak düşünülmektedir. Proteinden sınırlı, düşük karbonhidrat ve yüksek yağ içeriğine sahip KD uygulamaları daha önceleri son çare olarak uygulanırken günümüzde sıklıkla kullanılan bir tedavi haline gelmiştir. Diyetteki karbonhidrat içeriğinin düşük ve yağ içeriğinin yüksek olması nedeniyle kanda keton cisimlerinin artışı söz konusudur. Keton cisimlerinin artışıyla beyin keton cisimlerini enerji kaynağı olarak kullanmakta ve epileptik nöbetlerde azalma görülmektedir. Çocukluk döneminde epilepsi tedavisi süresince yapılan beslenme tedavisi normal büyüme ve gelişmeyi sağlamalıdır. Bunun için de diyete uyumun tam olması oldukça önemlidir. Bu derlemede çocukluk çağı dirençli epilepsilerinde KD’nin etkisi, yeri ve önemi irdelenmiştir.
Anahtar Kelime:

Konular: Nörolojik Bilimler
Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık
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APA ÖZATA UYAR G, Sanlier N (2018). The Effect of Ketogenic Diet Treatment in Drug-resistant Epilepsies of Childhood. , 216 - 225.
Chicago ÖZATA UYAR GİZEM,Sanlier Nevin The Effect of Ketogenic Diet Treatment in Drug-resistant Epilepsies of Childhood. (2018): 216 - 225.
MLA ÖZATA UYAR GİZEM,Sanlier Nevin The Effect of Ketogenic Diet Treatment in Drug-resistant Epilepsies of Childhood. , 2018, ss.216 - 225.
AMA ÖZATA UYAR G,Sanlier N The Effect of Ketogenic Diet Treatment in Drug-resistant Epilepsies of Childhood. . 2018; 216 - 225.
Vancouver ÖZATA UYAR G,Sanlier N The Effect of Ketogenic Diet Treatment in Drug-resistant Epilepsies of Childhood. . 2018; 216 - 225.
IEEE ÖZATA UYAR G,Sanlier N "The Effect of Ketogenic Diet Treatment in Drug-resistant Epilepsies of Childhood." , ss.216 - 225, 2018.
ISNAD ÖZATA UYAR, GİZEM - Sanlier, Nevin. "The Effect of Ketogenic Diet Treatment in Drug-resistant Epilepsies of Childhood". (2018), 216-225.
APA ÖZATA UYAR G, Sanlier N (2018). The Effect of Ketogenic Diet Treatment in Drug-resistant Epilepsies of Childhood. Türk Nöroloji Dergisi, 24(3), 216 - 225.
Chicago ÖZATA UYAR GİZEM,Sanlier Nevin The Effect of Ketogenic Diet Treatment in Drug-resistant Epilepsies of Childhood. Türk Nöroloji Dergisi 24, no.3 (2018): 216 - 225.
MLA ÖZATA UYAR GİZEM,Sanlier Nevin The Effect of Ketogenic Diet Treatment in Drug-resistant Epilepsies of Childhood. Türk Nöroloji Dergisi, vol.24, no.3, 2018, ss.216 - 225.
AMA ÖZATA UYAR G,Sanlier N The Effect of Ketogenic Diet Treatment in Drug-resistant Epilepsies of Childhood. Türk Nöroloji Dergisi. 2018; 24(3): 216 - 225.
Vancouver ÖZATA UYAR G,Sanlier N The Effect of Ketogenic Diet Treatment in Drug-resistant Epilepsies of Childhood. Türk Nöroloji Dergisi. 2018; 24(3): 216 - 225.
IEEE ÖZATA UYAR G,Sanlier N "The Effect of Ketogenic Diet Treatment in Drug-resistant Epilepsies of Childhood." Türk Nöroloji Dergisi, 24, ss.216 - 225, 2018.
ISNAD ÖZATA UYAR, GİZEM - Sanlier, Nevin. "The Effect of Ketogenic Diet Treatment in Drug-resistant Epilepsies of Childhood". Türk Nöroloji Dergisi 24/3 (2018), 216-225.
Sayfa Oluşturulma Tarihi
23-04-2024 7:59

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