Diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration in elderly patients
Yıl: 2018 Cilt: 66 Sayı: 2 Sayfa Aralığı: 115 - 121 Metin Dili: İngilizce DOI: 10.5578/tt.67020 İndeks Tarihi: 01-07-2019
Diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration in elderly patients
Öz: Introduction: In the elderly population, diagnosis and initial treatment should be considered as soon as possible because of co-morbidities and complications. We aimed to evaluate the findings of endobronchial ultrasound-guided transbronchial needle aspiration(EBUS-TBNA) to determine the diagnostic utility of EBUS-TBNA in patients 65 years of age and older.Materials and Methods: We retrospectively evaluated records of patients who underwent EBUS-TBNA from February 2014 to August2017 for diagnosis and/or staging. The demographic data, clinical and EBUS findings, diagnostic procedures during EBUS-TBNA andthe incidence of accurate diagnosis with EBUS-TBNA in patients 65 years of age and older and in younger patients were determined.Results: A total of 496 patients [younger patients (< 65 years, n= 293, M/F: 198/95) and older patients (≥ 65 years, n= 203, M/F:155/48)] who underwent EBUS-TBNA at our clinic were included. The mean age of the older patients was 69.7 ± 5.1 years, whilethe mean age of the younger patients was 51.4 ± 10.4 years. Overall, the diagnostic accuracy of EBUS-TBNA was 96.5% in the olderpatients and 98% in the younger patients. The diagnostic utility of EBUS-TBNA in the two study groups was similar (p= 0.191). While196 (96.6%) of the older patients had no complications during EBUS-TBNA, 285 (97.3%) of the younger patients had nocomplications. Complication rates were not statistically different between the two groups (p= 0.389).Conclusion: In general, EBUS-TBNA is a safe method. The results of this study demonstrated the high diagnostic value of EBUS-TBNAand its low complication rates in patients 65 years of age and older.
Anahtar Kelime: Konular:
Yaşlı hastalarda endobronşiyal ultrason eşliğinde alınan transbronşiyal iğne aspirasyonunun tanı değeri
Öz: Giriş: Yaşlı nüfusta, komorbidite ve komplikasyonlar nedeniyle tanı ve tedavi en kısa zamanda düşünülmelidir. Bu yazıda 65 yaş ve üzerindeki hastalarda endobronşiyal ultrasonografi eşliğinde alınan transbronşiyal iğne aspirasyonunun (EBUS-TBİA) kullanımı ve tanı başarısını değerlendirmeyi amaçladık. Materyal ve Metod: Şubat 2014-Ağustos 2017 tarihleri arasında tanı ve/veya evreleme amaçlı EBUS-TBİA uygulanan hastaların kayıtlarını retrospektif olarak değerlendirdik. Altmış beş yaş ve üzeri ve daha genç hastaların demografik verileri, klinik ve EBUS bulguları, EBUS-TBİA sırasında işlem bilgileri ve işlemin tanı değeri kaydedildi. Bulgular: Kliniğimizde EBUS-TBİA uygulanan 496 hasta [ genç hastalar (< 65 yaş, n= 293, E/K: 198/95) ve yaşlı hastalar (≥ 65 yaş, n= 203, M/F: 155/48)] dahil edildi. Yaşlı hastaların ortalama yaşı 69.7 ± 5.1 yıl iken, daha genç yaştaki hastaların yaş ortalaması 51.4 ± 10.4 idi. Genel olarak, EBUS-TBİA’nın tanısal doğruluğu yaşlı hastalarda %96.5, genç hastalarda %98'idi. Her iki grupta da EBUS-TBİA’nın tanı değeri benzerdi (p= 0.191). EBUS-TBİA sırasında yaşlı hastaların 196’sında (%96.6) herhangi bir komplikasyon görülmezken, genç hastaların 285'inde (%97.3) komplikasyon gelişmedi. Komplikasyon oranlarına bakıldığında iki grup arasında istatistiksel olarak anlamlı fark yoktu (p= 0.389). Sonuç: Genel olarak, EBUS-TBİA güvenli bir yöntemdir. Bu çalışmanın sonuçları 65 yaş ve üstündeki hastalarda EBUS-TBİA’nın yüksek tanısal değerini ve düşük komplikasyon oranlarını ortaya koymuştur.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
- Venuta F, Diso D, Onorati I, Anile M, Mantovani S, Rendina EA. Lung cancer in elderly patients. J Thorac Dis 2016;8(Suppl 11):S908-S914.
- Agarwal R, Srinivasan A, Aggarwal AN, Gupta D. Efficacy and safety of convex probe EBUS-TBNA in sarcoidosis: a systematic review and meta-analysis. Respir Med 2012;106:883-92.
- Gu P, Zhao YZ, Jiang LY, Zhang W, Xin Y, Han BH. Endobronchial ultrasound guided transbronchial needle aspiration for staging of lung cancer: a systematic review and meta-analysis. Eur J Cancer 2009;45:1389-96.
- Evison M, Crosbie PA, Martin J, Bishop P, Doran H, Joseph L, et al. EBUS-TBNA in elderly patients with lung cancer: safety and performance outcomes. J Thorac Oncol 2014;9:370-6.
- Eapen GA, Shah AM, Lei X, Jimenez CA, Morice RC, Yarmus L, et al. American College of Chest Physicians Quality Improvement Registry, Education. Complications, consequences, and practice patterns of endobronchial ultrasound-guided transbronchial needle aspiration: results of the AQuIRE registry. Chest 2013;143:1044-53.
- Honeybourne D, Babb J, Bowie P, et al. British Thoracic Society guidelines on diagnostic flexible bronchoscopy. Thorax 2001;56(Suppl 1):i1-21.
- Vaidya PJ, Kate AH, Yasufuku K, Chhajed PN. Endobronchial ultrasound-guided transbronchial needle aspiration in lung cancer diagnosis and staging. Expert Rev Respir Med 2015;9:45-53.
- Cetinkaya E, Gunluoglu G, Ozgul A, Gunluoglu MZ, Ozgul G, Seyhan EC, et al. Value of real-time endobronchial ultrasound-guided transbronchial needle aspiration. Ann Thorac Med 2011;6:77-81.
- Yasufuku K. EBUS-TBNA Bronchoscopy. In: Ernst A, Herth F.J.F, editors. Endobronchial Ultrasound An Atlas and Practical Guide. Dordrecht Heidelberg London New York: Springer, 2009:119-45.
- Maione P, Rossi A, Sacco PC, Bareschino MA, Schettino C, Ferrara ML, et al. Treating advanced non-small cell lung cancer in the elderly. Ther Adv Med Oncol 2010;2:251- 60.
- Baughman RP, Teirstein AS, Judson MA, Rossman MD, Yeager H Jr, Bresnitz EA, et al. Clinical characteristics of patients in a case control study of sarcoidosis. Am J Respir Crit Care Med 2001;164:1885-9.
- Okubo Y, Matsumoto Y, Nakai T, Tsuchida T, Asakura K, Motoi N, et al. The new transbronchial diagnostic approach for the metastatic lung tumor from renal cell carcinoma-a case report. J Thorac Dis 2017;9:E762-E766.
- Vaidya PJ, Munavvar M, Leuppi JD, Mehta AC, Chhajed PN. Endobronchial ultrasound-guided transbronchial needle aspiration: Safe as it sounds. Respirology 2017;22:1093- 101.
- Du Rand IA, Blaikley J, Booton R, Chaudhuri N, Gupta V, Khalid S, et al.; British Thoracic Society Bronchoscopy Guideline Group. British Thoracic Society guideline for diagnostic flexible bronchoscopy in adults: accredited by NICE. Thorax 2013;68(Suppl 1):i1-i44.
- Casal RF, Lazarus DR, Kuhl K, Nogueras-González G, Perusich S, Green LK, et al. Randomized trial of endobronchial ultrasound-guided transbronchial needle aspiration under general anesthesia versus moderate sedation. Am J Respir Crit Care Med 2015;191:796-803.
| APA | YILMAZ DEMİRCİ N, ÖZTÜRK C (2018). Diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration in elderly patients. , 115 - 121. 10.5578/tt.67020 |
| Chicago | YILMAZ DEMİRCİ Nilgün,ÖZTÜRK Can Diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration in elderly patients. (2018): 115 - 121. 10.5578/tt.67020 |
| MLA | YILMAZ DEMİRCİ Nilgün,ÖZTÜRK Can Diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration in elderly patients. , 2018, ss.115 - 121. 10.5578/tt.67020 |
| AMA | YILMAZ DEMİRCİ N,ÖZTÜRK C Diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration in elderly patients. . 2018; 115 - 121. 10.5578/tt.67020 |
| Vancouver | YILMAZ DEMİRCİ N,ÖZTÜRK C Diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration in elderly patients. . 2018; 115 - 121. 10.5578/tt.67020 |
| IEEE | YILMAZ DEMİRCİ N,ÖZTÜRK C "Diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration in elderly patients." , ss.115 - 121, 2018. 10.5578/tt.67020 |
| ISNAD | YILMAZ DEMİRCİ, Nilgün - ÖZTÜRK, Can. "Diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration in elderly patients". (2018), 115-121. https://doi.org/10.5578/tt.67020 |
| APA | YILMAZ DEMİRCİ N, ÖZTÜRK C (2018). Diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration in elderly patients. Tüberküloz ve Toraks, 66(2), 115 - 121. 10.5578/tt.67020 |
| Chicago | YILMAZ DEMİRCİ Nilgün,ÖZTÜRK Can Diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration in elderly patients. Tüberküloz ve Toraks 66, no.2 (2018): 115 - 121. 10.5578/tt.67020 |
| MLA | YILMAZ DEMİRCİ Nilgün,ÖZTÜRK Can Diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration in elderly patients. Tüberküloz ve Toraks, vol.66, no.2, 2018, ss.115 - 121. 10.5578/tt.67020 |
| AMA | YILMAZ DEMİRCİ N,ÖZTÜRK C Diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration in elderly patients. Tüberküloz ve Toraks. 2018; 66(2): 115 - 121. 10.5578/tt.67020 |
| Vancouver | YILMAZ DEMİRCİ N,ÖZTÜRK C Diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration in elderly patients. Tüberküloz ve Toraks. 2018; 66(2): 115 - 121. 10.5578/tt.67020 |
| IEEE | YILMAZ DEMİRCİ N,ÖZTÜRK C "Diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration in elderly patients." Tüberküloz ve Toraks, 66, ss.115 - 121, 2018. 10.5578/tt.67020 |
| ISNAD | YILMAZ DEMİRCİ, Nilgün - ÖZTÜRK, Can. "Diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration in elderly patients". Tüberküloz ve Toraks 66/2 (2018), 115-121. https://doi.org/10.5578/tt.67020 |
