Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B
Yıl: 2018 Cilt: 24 Sayı: 2 Sayfa Aralığı: 59 - 62 Metin Dili: İngilizce DOI: 10.4274/tod.04796 İndeks Tarihi: 12-07-2019
Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B
Öz: Adefovir dipivoxil (ADV) is a nucleotide analogue used in the chronic hepatitis B treatment. Proximal renal tubular dysfunction is one of the adverse effects of this agent and characterized with hypophosphatemia and osteomalacia. However, reduced bone mineral density with fracture due to ADV therapy has not been reported before. We aimed to report a 55-year-old male patient with proximal femur fracture who developed hypophosphatemic osteomalacia while using low dose of adefovir (10 mg/day) for chronic hepatitis B treatment for 10 years.
Anahtar Kelime: Konular:
Kronik Hepatit B’li Hastada Adefovir Tedavisi Sonrası Gelişen Osteoporoz ve Hipofosfatemik Osteomalaziye Bağlı Patolojik Femur Kırığı
Öz: Adefovir dipivoksil (ADV), kronik hepatit tedavisinde kullanılan bir nükleotid analoğudur. Proksimal renal tübüler fonksiyon bozukluğu, bu ajanın yan etkilerinden biridir ve hipofosfatemi ve osteomalazi ile karakterizedir. Bununla birlikte, ADV tedavisine bağlı kırık ile kemik mineral dansitesinde azalma daha önce bildirilmemiştir. Burada 10 yıldır kronik hepatit B tedavisi için düşük dozda adefovir kullanan (10 mg/gün) 55 yaşındaki erkek hastada hipofosfatemik osteomalazi sonucu gelişen proksimal femur kırığı olan bir hastayı bildirmeyi amaçladık.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık
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| APA | Batıbay S, GELER KÜLCÜ D, Mesci N, ÇAĞLAR RUHİ B, ŞAHİN Z, GÜNDOĞDU H (2018). Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B. , 59 - 62. 10.4274/tod.04796 |
| Chicago | Batıbay Sevilay,GELER KÜLCÜ Duygu,Mesci Nilgün,ÇAĞLAR RUHİ Borçak,ŞAHİN Zerrin,GÜNDOĞDU Hasan Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B. (2018): 59 - 62. 10.4274/tod.04796 |
| MLA | Batıbay Sevilay,GELER KÜLCÜ Duygu,Mesci Nilgün,ÇAĞLAR RUHİ Borçak,ŞAHİN Zerrin,GÜNDOĞDU Hasan Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B. , 2018, ss.59 - 62. 10.4274/tod.04796 |
| AMA | Batıbay S,GELER KÜLCÜ D,Mesci N,ÇAĞLAR RUHİ B,ŞAHİN Z,GÜNDOĞDU H Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B. . 2018; 59 - 62. 10.4274/tod.04796 |
| Vancouver | Batıbay S,GELER KÜLCÜ D,Mesci N,ÇAĞLAR RUHİ B,ŞAHİN Z,GÜNDOĞDU H Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B. . 2018; 59 - 62. 10.4274/tod.04796 |
| IEEE | Batıbay S,GELER KÜLCÜ D,Mesci N,ÇAĞLAR RUHİ B,ŞAHİN Z,GÜNDOĞDU H "Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B." , ss.59 - 62, 2018. 10.4274/tod.04796 |
| ISNAD | Batıbay, Sevilay vd. "Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B". (2018), 59-62. https://doi.org/10.4274/tod.04796 |
| APA | Batıbay S, GELER KÜLCÜ D, Mesci N, ÇAĞLAR RUHİ B, ŞAHİN Z, GÜNDOĞDU H (2018). Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B. Türk Osteoporoz Dergisi, 24(2), 59 - 62. 10.4274/tod.04796 |
| Chicago | Batıbay Sevilay,GELER KÜLCÜ Duygu,Mesci Nilgün,ÇAĞLAR RUHİ Borçak,ŞAHİN Zerrin,GÜNDOĞDU Hasan Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B. Türk Osteoporoz Dergisi 24, no.2 (2018): 59 - 62. 10.4274/tod.04796 |
| MLA | Batıbay Sevilay,GELER KÜLCÜ Duygu,Mesci Nilgün,ÇAĞLAR RUHİ Borçak,ŞAHİN Zerrin,GÜNDOĞDU Hasan Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B. Türk Osteoporoz Dergisi, vol.24, no.2, 2018, ss.59 - 62. 10.4274/tod.04796 |
| AMA | Batıbay S,GELER KÜLCÜ D,Mesci N,ÇAĞLAR RUHİ B,ŞAHİN Z,GÜNDOĞDU H Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B. Türk Osteoporoz Dergisi. 2018; 24(2): 59 - 62. 10.4274/tod.04796 |
| Vancouver | Batıbay S,GELER KÜLCÜ D,Mesci N,ÇAĞLAR RUHİ B,ŞAHİN Z,GÜNDOĞDU H Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B. Türk Osteoporoz Dergisi. 2018; 24(2): 59 - 62. 10.4274/tod.04796 |
| IEEE | Batıbay S,GELER KÜLCÜ D,Mesci N,ÇAĞLAR RUHİ B,ŞAHİN Z,GÜNDOĞDU H "Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B." Türk Osteoporoz Dergisi, 24, ss.59 - 62, 2018. 10.4274/tod.04796 |
| ISNAD | Batıbay, Sevilay vd. "Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B". Türk Osteoporoz Dergisi 24/2 (2018), 59-62. https://doi.org/10.4274/tod.04796 |
