TY  - JOUR
TI  - Chemical Profile of Malva Neglecta and Malvella Sherardiana by LcMS/MS, GC/MS and Their Anticholinesterase, Antimicrobial and Antioxidant Properties With Aflatoxin-Contents
AB  - The purpose of the present work was to calculate the phenolicand the fatty acids profiles by LC-MS/MS and GC/MS with theirantioxidant, anticholinesterase and antimicrobial activities, andaflatoxin contents of Malva neglecta and Malvella sherardiana.The phenolic contents of M. neglecta and M. sherardiana weredetermined by LC-MS/MS. Malic and 4-OH benzoic acids werefound to be the most abundant compounds in M. neglecta and M.sherardiana, respectively. On the other hand, essential oils andfatty acids composition were determined by GC/MS analysis.The methanol extracts of the plants showed the highest effectin all antioxidant assays of this study. The methanol extract ofM. neglecta showed the highest activity among the petroleumether, acetone, methanol and water extracts against acetyl- andbutyryl- cholinesterase enzymes (53.68% and 63.95% inhibitionratio, respectively). The acetone extracts of M. neglacta and M.sherardiana exhibited moderate activity against C. albicans with18 and 17 mm inhibion zone diameter, respectively. The resultsof the present study is also showed that the M. neglecta and M.sherardiana can also be used as a food source due to its highphenolic acid content and good antioxidant property. Also, thesamples were aflatoxin free.
AU  - YENER, Ismail
AU  - HAŞİMİ, NESRİN
AU  - ALKAN, MEHMET HÜSEYİN
AU  - KOLAK, UFUK
AU  - Ozaslan, Cumali
AU  - Boga, Mehmet
AU  - ERTAŞ, ABDULSELAM
AU  - VARHAL ORAL, Elif
AU  - YILMAZ, Mustafa Abdullah
AU  - Gazioğlu, Işıl
AU  - Akdeniz, Mehmet
DO  - 10.12991/marupj.307461
PY  - 2017
JO  - Marmara Pharmaceutical Journal
VL  - 21
IS  - 3
SN  - 1309-0801
SP  - 471
EP  - 484
DB  - TRDizin
UR  - http://search/yayin/detay/302734
ER  -