Yıl: 2018 Cilt: 44 Sayı: 6 Sayfa Aralığı: 498 - 502 Metin Dili: İngilizce DOI: 10.5152/tud.2018.98372 İndeks Tarihi: 25-07-2019

Delayed diagnosis of primary vesicoureteral reflux in children with recurrent urinary tract infections: Diagnostic approach and renal outcomes

Öz:
Objective: In this study, we aimed to assess renal outcomes of delayed diagnosis of dilating primary vesicoureteral reflux (VUR) following recurrent febrile urinary tract infections (fUTIs) and its diagnostic imagingprocedures.Material and methods: The medical records of patients who underwent ultrasonography (US), non- acutedimercaptosuccinic acid (Tc-99mDMSA) scintigraphy and voiding cystourethrography (VCUG), and whowere older than 2 years at the time of VUR diagnosis were retrospectively reviewed.Results: A total of 32 children (female, n=27: 84.4%) with a mean age of 7.67±3.34 years at the time ofdiagnosis of VUR were included in the study. Grade III, IV, V VUR were found in 22%, 69%, and 9%of the patients, respectively. At the time of VUR diagnosis, abnormal US findings were detected in 75%of the cases. Tc-99mDMSA detected abnormalities in 83.9% (7 with a single scar, 7 with multiple lesions,12 with reduced kidney function) of the patients. Estimated glomerular filtration rate of 3 patients withbilateral grade IV VUR was <75 mL/min/1.73 m2. In 5 patients (16%), VUR could not be predicted byUS+DMSA scintigraphy (Grade IV VUR in 3 and Grade III in 2 cases ). The sensitivity in predicting VURwas 75.00% (95% CI: 56.60-88.54) and 83.87% (95% CI: 66.27-94.55), respectively, for US alone and combined US+DMSA.Conclusion: VCUG should be performed routinely in addition to US and non-acute DMSA in all childrenreferred with recurrent fUTIs. Awareness of childhood UTI in public and healthcare personnels should beincreased in order to refer these patients at a early stage to pediatric urology and nephrology units.
Anahtar Kelime:

Konular: Üroloji ve Nefroloji
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA Dogan C, SEMERCİ KOYUN N, KAYA AKSOY G, çekiç b, savas m, Çomak E (2018). Delayed diagnosis of primary vesicoureteral reflux in children with recurrent urinary tract infections: Diagnostic approach and renal outcomes. , 498 - 502. 10.5152/tud.2018.98372
Chicago Dogan Cagla Serpil,SEMERCİ KOYUN Nevin,KAYA AKSOY Gülşah,çekiç bülent,savas murat,Çomak Elif Delayed diagnosis of primary vesicoureteral reflux in children with recurrent urinary tract infections: Diagnostic approach and renal outcomes. (2018): 498 - 502. 10.5152/tud.2018.98372
MLA Dogan Cagla Serpil,SEMERCİ KOYUN Nevin,KAYA AKSOY Gülşah,çekiç bülent,savas murat,Çomak Elif Delayed diagnosis of primary vesicoureteral reflux in children with recurrent urinary tract infections: Diagnostic approach and renal outcomes. , 2018, ss.498 - 502. 10.5152/tud.2018.98372
AMA Dogan C,SEMERCİ KOYUN N,KAYA AKSOY G,çekiç b,savas m,Çomak E Delayed diagnosis of primary vesicoureteral reflux in children with recurrent urinary tract infections: Diagnostic approach and renal outcomes. . 2018; 498 - 502. 10.5152/tud.2018.98372
Vancouver Dogan C,SEMERCİ KOYUN N,KAYA AKSOY G,çekiç b,savas m,Çomak E Delayed diagnosis of primary vesicoureteral reflux in children with recurrent urinary tract infections: Diagnostic approach and renal outcomes. . 2018; 498 - 502. 10.5152/tud.2018.98372
IEEE Dogan C,SEMERCİ KOYUN N,KAYA AKSOY G,çekiç b,savas m,Çomak E "Delayed diagnosis of primary vesicoureteral reflux in children with recurrent urinary tract infections: Diagnostic approach and renal outcomes." , ss.498 - 502, 2018. 10.5152/tud.2018.98372
ISNAD Dogan, Cagla Serpil vd. "Delayed diagnosis of primary vesicoureteral reflux in children with recurrent urinary tract infections: Diagnostic approach and renal outcomes". (2018), 498-502. https://doi.org/10.5152/tud.2018.98372
APA Dogan C, SEMERCİ KOYUN N, KAYA AKSOY G, çekiç b, savas m, Çomak E (2018). Delayed diagnosis of primary vesicoureteral reflux in children with recurrent urinary tract infections: Diagnostic approach and renal outcomes. Turkish Journal of Urology, 44(6), 498 - 502. 10.5152/tud.2018.98372
Chicago Dogan Cagla Serpil,SEMERCİ KOYUN Nevin,KAYA AKSOY Gülşah,çekiç bülent,savas murat,Çomak Elif Delayed diagnosis of primary vesicoureteral reflux in children with recurrent urinary tract infections: Diagnostic approach and renal outcomes. Turkish Journal of Urology 44, no.6 (2018): 498 - 502. 10.5152/tud.2018.98372
MLA Dogan Cagla Serpil,SEMERCİ KOYUN Nevin,KAYA AKSOY Gülşah,çekiç bülent,savas murat,Çomak Elif Delayed diagnosis of primary vesicoureteral reflux in children with recurrent urinary tract infections: Diagnostic approach and renal outcomes. Turkish Journal of Urology, vol.44, no.6, 2018, ss.498 - 502. 10.5152/tud.2018.98372
AMA Dogan C,SEMERCİ KOYUN N,KAYA AKSOY G,çekiç b,savas m,Çomak E Delayed diagnosis of primary vesicoureteral reflux in children with recurrent urinary tract infections: Diagnostic approach and renal outcomes. Turkish Journal of Urology. 2018; 44(6): 498 - 502. 10.5152/tud.2018.98372
Vancouver Dogan C,SEMERCİ KOYUN N,KAYA AKSOY G,çekiç b,savas m,Çomak E Delayed diagnosis of primary vesicoureteral reflux in children with recurrent urinary tract infections: Diagnostic approach and renal outcomes. Turkish Journal of Urology. 2018; 44(6): 498 - 502. 10.5152/tud.2018.98372
IEEE Dogan C,SEMERCİ KOYUN N,KAYA AKSOY G,çekiç b,savas m,Çomak E "Delayed diagnosis of primary vesicoureteral reflux in children with recurrent urinary tract infections: Diagnostic approach and renal outcomes." Turkish Journal of Urology, 44, ss.498 - 502, 2018. 10.5152/tud.2018.98372
ISNAD Dogan, Cagla Serpil vd. "Delayed diagnosis of primary vesicoureteral reflux in children with recurrent urinary tract infections: Diagnostic approach and renal outcomes". Turkish Journal of Urology 44/6 (2018), 498-502. https://doi.org/10.5152/tud.2018.98372