TY  - JOUR
TI  - Does the prostate volume always effect cancer detection rate in prostate biopsy? Additional role of prostate-specific antigen levels: A retrospective analysis of 2079 patients
AB  - Objective: We aimed to determine whether the effect of prostate volume on cancer detection rates is influenced by serum prostate-specific antigen (PSA).Material and methods: A total of 2465 men who underwent transrectal ultrasound-guided biopsy were retrospectively evaluated. Standard 10-core prostate biopsy was performed in all cases. Patients were dividedinto three groups according to the serum PSA levels: ≤10 ng/mL (Group 1), 10- 20 ng/mL (Group 2) and >20ng/mL (Group 3). In each group age, serum PSA levels and prostate volumes were compared in patients withand without prostate cancer.Results: A total of 2079 patients were included in the study group. Cancer detection rates were 16%, 25%,53% in Groups 1, 2 and 3, respectively (p=0.001). In Group 1, there was a significant difference in meanprostate volume of patients with and without prostate cancer (p=0.01). However, this difference was not seenin Group 2 or 3 (p=0.06 and p=0.08, respectively). The mean age and PSA level which are the other determinants of prostate cancer diagnosis were similar between patients with and without cancer in the Group 1,thus prostate volume was the only determinant of the diagnosis.Conclusion: According to our findings, prostate volume is an important factor for prostate cancer diagnosedwith prostate biopsy only in patients with a PSA level of ≤10 ng/mL.
AU  - Semerciöz, Atilla
AU  - Colakerol, Aykut
AU  - Muslumanoglu, Ahmet Yaser
AU  - YÜRÜK, Emrah
AU  - temiz, mustafa
AU  - Kandirali, Engin
DO  - 10.5152/tud.2018.66909
PY  - 2019
JO  - Turkish Journal of Urology
VL  - 45
IS  - 2
SN  - 2149-3235
SP  - 103
EP  - 107
DB  - TRDizin
UR  - http://search/yayin/detay/303742
ER  -