Objectives: With the increase in technology, nowadays cancer has become a chronic disease that requires long‐term treatment and care at home thus affecting the whole family, rather than an acute disease resulting in death. We aimed to investigate the relationship between the depression and anxiety states of the patients and the depression and anxiety states of their caregivers in our study. Materials and Methods: Our study was carried out in Karadeniz Technical University Radiation Oncology Unit between June 2015 and May 2016 in a total of 100 patients and 100 their caregivers who agreed to participate in the study. A tailored questionnaire consisting of demographic features and Hospital Anxiety Depression Scale (HADS) questions was administered to patients. In addition to these, the Zarit Caregiver Scale was applied to caregivers. The main outcome measures were anxiety and depression scores. Results: The mean age of the patients was 55.41 ± 14.29, while that of the caregivers was 43.65 ± 13.64. Anxiety and depression states were significantly higher in the women than in the men (p<0.001, p = 0.009). There was a significantly positive correlation between depression scores of the patients and the anxiety score of the patients and the anxiety scores of the caregivers (r = 0.261, p = 0.009, r = 0.210, p = 0.036). Also, a significantly positive correlation was seen between the Zarit score and the caregiver's anxiety and depression scores (r = 0.569, p<0.001; r = 0.417, p<0.001). Conclusion: Being alert about the depression and anxiety that may occur in the individuals responsible for the care of cancer patients is required under the principle of maintaining and improving health.