Yıl: 2018 Cilt: 5 Sayı: 3 Sayfa Aralığı: 113 - 118 Metin Dili: İngilizce DOI: 10.4274/cayd.71463 İndeks Tarihi: 04-10-2019

Factors that Affect Prognosis and Morbidity in Pediatric Patients with Carbon Monoxide Poisoning

Öz:
Introduction: Carbonmonoxide poisoning continues to be a majorhealth problem worldwide, especially in developing countries,and constitutes an important part of the patients admitted to thepediatric emergency clinics due to poisoning. The aim of this studywas to evaluate the correlation between clinical severity, morbidity,hospital stay, intensive care need, and full systemic effects in patientswho were followed up and treated for carbon monoxide poisoningin our pediatric emergency clinic.Methods: The study was performed between January 2013 and2015. We included patients under 18 years of age who were admittedto the pediatric emergency with carbon monoxide poisoning.Assessments were made prospectively. The epidemiologicalcharacteristics, complaints, physical examination and vital findingsof all patients were recorded. Carboxyhemoglobin (COHb) level,oxygen saturation, electrocardiography, complete blood count,liver and kidney functions, and cardiac enzymes were studied, andGlasgow Coma scale (GCS) was calculated.Results: The mean length of hospital stay for 232 patients wascalculated as 7.08±1 hours and the mean duration of exposure tocarbon monoxide gas was 3.17±2.5 hours. Higher COHb levels andcardiotoxicity were detected in patients with a longer duration ofexposure and a lower GCS and an increased intensive care need(p<0.01). There was no correlation between COHb levels and clinicalseverity, GCS, or intensive care unit need. However, it was foundthat high COHb levels (especially above 30%) increased cardiacinjury and neurological symptoms but did not cause a permanentsequela (p<0.05). None of the patients had permanent neurological,cardiac, or renal damage.Conclusion: We found that duration of exposure is the mostimportant and accurate parameter for the evaluation of clinicalcourse and morbidity. In patients with high COHb levels, the effectsare more prominent, however, we considered that there was nochange in sequelae at long-term follow up.
Anahtar Kelime:

Konular: Acil Tıp Pediatri

Karbonmonoksit Zehirlenmesi Olan Çocuk Hastalarda Prognoz ve Morbiditiye Etkileyen Faktörler

Öz:
Giriş: Karbonmonoksit zehirlenmesi başta gelişmekte olan ülkelerde olmak üzere tüm dünyada önemli bir sağlık problemi olmaya devam etmekte ve zehirlenme nedeniyle çocuk acil servislerine başvuran hastaların önemli bir bölümünü oluşturmaktadır. Bu çalışmanın amacı, çocuk acil servisimizde karbonmonoksit zehirlenmesi nedeniyle takip ve tedavi edilen hastalarda klinik şiddet, morbidite, hastanede kalış süresi, yoğun bakım ihtiyacı ve sistemik etkiler arasındaki ilişkiyi araştırmaktır. Yöntemler: Çalışmaya karbonmonoksit zehirlenmesi ile başvuran çocuk acile başvuran 18 yaş altı 232 çocuk dahil edildi. Değerlendirme ileriye yönelik olarak yapıldı. Tüm hastaların epidemiyolojik özellikleri, şikayetleri, fizik muayene ve yaşamsal bulguları kaydedildi. Karboksihemoglobin düzeyi, oksijen satürasyonu, elektrokardiyografi, tam kan sayımı, karaciğer ve böbrek fonksiyonları, kardiyak enzimler çalışıldı ve Glasgow Koma skoru (GKS) hesaplandı. Bulgular: İki yüz otuz iki hasta için ortalama yatış süresi 7,08±1 saat olarak hesaplandı ve ortalama karbonmonoksit gazına maruz kalma süresi 3,17±2,5 saat olarak hesaplandı. Daha uzun süre maruz kalan hastalarda daha yüksek karboksihemoglobin düzeyleri ve kardiyotoksisite, azalmış GKS ve artmış yoğun bakım ihtiyacı saptanmıştır (p<0,01). Karboksihemoglobin düzeyleri ile hastanın klinik şiddeti, GKS ve yoğun bakım ihtiyacı arasında korelasyon yokken (p>0,05) özellikle %30 ve üzeri seviyelerde kardiyak ve nörolojik hasarı artırdığı saptanmıştır. Hiçbir hastada kalıcı nörolojik, kardiyak veya renal hasar gelişmedi. Sonuç: Karbonmonoksit gazına uzun süre maruz kalmanın morbiditeyi artırdığını ve diğer epidemiyolojik, klinik ve laboratuvar parametrelerine önemli bir etkisi olmadığını ve yüksek orandaki karboksihemoglobin seviyelerinde organ etkileniminin belirginleştiği ancak sekel değişiklik bırakmadığını değerlendirdik.
Anahtar Kelime:

Konular: Acil Tıp Pediatri
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA SEÇİLMİŞ Y, öztürk a (2018). Factors that Affect Prognosis and Morbidity in Pediatric Patients with Carbon Monoxide Poisoning. , 113 - 118. 10.4274/cayd.71463
Chicago SEÇİLMİŞ Yılmaz,öztürk adnan Factors that Affect Prognosis and Morbidity in Pediatric Patients with Carbon Monoxide Poisoning. (2018): 113 - 118. 10.4274/cayd.71463
MLA SEÇİLMİŞ Yılmaz,öztürk adnan Factors that Affect Prognosis and Morbidity in Pediatric Patients with Carbon Monoxide Poisoning. , 2018, ss.113 - 118. 10.4274/cayd.71463
AMA SEÇİLMİŞ Y,öztürk a Factors that Affect Prognosis and Morbidity in Pediatric Patients with Carbon Monoxide Poisoning. . 2018; 113 - 118. 10.4274/cayd.71463
Vancouver SEÇİLMİŞ Y,öztürk a Factors that Affect Prognosis and Morbidity in Pediatric Patients with Carbon Monoxide Poisoning. . 2018; 113 - 118. 10.4274/cayd.71463
IEEE SEÇİLMİŞ Y,öztürk a "Factors that Affect Prognosis and Morbidity in Pediatric Patients with Carbon Monoxide Poisoning." , ss.113 - 118, 2018. 10.4274/cayd.71463
ISNAD SEÇİLMİŞ, Yılmaz - öztürk, adnan. "Factors that Affect Prognosis and Morbidity in Pediatric Patients with Carbon Monoxide Poisoning". (2018), 113-118. https://doi.org/10.4274/cayd.71463
APA SEÇİLMİŞ Y, öztürk a (2018). Factors that Affect Prognosis and Morbidity in Pediatric Patients with Carbon Monoxide Poisoning. Çocuk Acil ve Yoğun Bakım Dergisi, 5(3), 113 - 118. 10.4274/cayd.71463
Chicago SEÇİLMİŞ Yılmaz,öztürk adnan Factors that Affect Prognosis and Morbidity in Pediatric Patients with Carbon Monoxide Poisoning. Çocuk Acil ve Yoğun Bakım Dergisi 5, no.3 (2018): 113 - 118. 10.4274/cayd.71463
MLA SEÇİLMİŞ Yılmaz,öztürk adnan Factors that Affect Prognosis and Morbidity in Pediatric Patients with Carbon Monoxide Poisoning. Çocuk Acil ve Yoğun Bakım Dergisi, vol.5, no.3, 2018, ss.113 - 118. 10.4274/cayd.71463
AMA SEÇİLMİŞ Y,öztürk a Factors that Affect Prognosis and Morbidity in Pediatric Patients with Carbon Monoxide Poisoning. Çocuk Acil ve Yoğun Bakım Dergisi. 2018; 5(3): 113 - 118. 10.4274/cayd.71463
Vancouver SEÇİLMİŞ Y,öztürk a Factors that Affect Prognosis and Morbidity in Pediatric Patients with Carbon Monoxide Poisoning. Çocuk Acil ve Yoğun Bakım Dergisi. 2018; 5(3): 113 - 118. 10.4274/cayd.71463
IEEE SEÇİLMİŞ Y,öztürk a "Factors that Affect Prognosis and Morbidity in Pediatric Patients with Carbon Monoxide Poisoning." Çocuk Acil ve Yoğun Bakım Dergisi, 5, ss.113 - 118, 2018. 10.4274/cayd.71463
ISNAD SEÇİLMİŞ, Yılmaz - öztürk, adnan. "Factors that Affect Prognosis and Morbidity in Pediatric Patients with Carbon Monoxide Poisoning". Çocuk Acil ve Yoğun Bakım Dergisi 5/3 (2018), 113-118. https://doi.org/10.4274/cayd.71463