TY  - JOUR
TI  - Comparison of prostate biopsy pathology and radical prostatectomy pathologies
AB  - Objectives: The rate of prostate cancer has increased with the identification of the prostate-specific antigen; however,data on biopsy pathologies determined by transrectal ultrasonography may be incompatible with the pathologyindicated in radical prostatectomy specimens. This situation puts patients in need of curative treatment at risk whilein some patients they are overtreatment. The aim of this study was to compare Gleason scores in radicalprostatectomy specimens with the Gleason scores determined by transrectal ultrasound-guided biopsy pathologies.Methods: The data of patients who underwent radical prostatectomy in our clinic between January 2007 andNovember 2018 were evaluated retrospectively. Data included preoperative biopsy values, biopsy cores, biopsypercentage, Gleason scores from transrectal ultrasound-guided pre-biopsy biopsy cores, Gleason scores after radicalprostatectomy, tissue cancer rates, surgical margins, and pathological stage. The ISUP-WHO (Society of UrologicalPathology: ISUP-World Health Organization) 2014 classification was used for the pathological classification. Results: A total of 159 patients were evaluated. Transrectal ultrasonography-guided biopsy pathology revealed that82 (75.9%) patients with Gleason scores <7 had radical prostate pathology with Gleason scores of <7. Transrectalultrasonography-guided biopsy pathology revealed a Gleason score of 7 in 10 (38.4%) patients. The Gleason scorewas > 7 in 24 (48.9%) of the patients who had a Gleason score> 7 based on transrectal ultrasonography-guidedpathology. The radical pathology of 109 patients with biopsy pathology was ISUP 1 in 83 (76.1%) patients. The radicalpathology was ISUP 3 in 5 of 16 patients with biopsy pathology ISUP 3 (31.2%). Six patients with biopsy pathologyISUP 4 and 2 patients with ISUP 5 was reported at different stages.Conclusions: Differences occur between the Gleason scores reported in transrectal ultrasonography-guided biopsyand radical prostatectomy pathologies. These differences become more evident as age increases, as PSA levelincreases and as prostate volume decreases.
AU  - gökçe, hasan
AU  - ÇAMTOSUN, Ahmet
DO  - 10.5798/dicletip.534851
PY  - 2019
JO  - Dicle Tıp Dergisi
VL  - 46
IS  - 1
SN  - 1300-2945
SP  - 133
EP  - 136
DB  - TRDizin
UR  - http://search/yayin/detay/311314
ER  -