Yıl: 2019 Cilt: 15 Sayı: 1 Sayfa Aralığı: 8 - 13 Metin Dili: Türkçe DOI: 10.5505/yeditepe.2019.63634 İndeks Tarihi: 06-11-2019

Agresif periodontitisli hastalarda periodontal tedavinin oksidan ve antioksidan seviyeleri üzerine etkisi

Öz:
Amaç: Bu çalışmanın amacı, agresif periodontitisli hastalarda(AgP) dişeti oluğu sıvısında (DOS) İnterlökin-1beta (IL-1β) veoksidan-antioksidan seviyelerine cerrahi olmayan periodontal tedavinin etkilerini belirlemektir.Gereç ve Yöntem: Çalışma için sigara içmeyen periodontalolarak sağlıklı 12 birey ve generalize agresif periodontitisli(G-AgP) 14 bireyi içeren 26 kişi dahil edildi. Sondlanabilir cepderinliği (SCD), klinik ataşman seviyesi (KAS), gingival indeks(Gİ), plak indeksi (Pİ), sondlanamada kanama (SK) ölçüldü. Total oksidan seviyelerini(TOS) ve total antioksidan seviyelerini(TAS) belirlemek için her bir hastadan DOS örnekleri alındı.DOS ve klinik ölçümler başlangıçta ve periodontal tedaviden6 hafta sonra kaydedildi.Bulgular: Çalışma periodontal tedavi sonrası klinik parametrelerde istatistiksel olarak önemli iyileşme gösterdi. G-AgPhasta grubunda başlangıç ve 6.hafta arasında DOS IL-1βseviyeleri arasında önemli bir farklılık yoktu (p>0,05). G-AgPhastalarında TOS seviyesinin 6. haftada başlangıçtan önemliölçüde azaldığı bulundu (p<0,05).Sonuçlar: Çalışmanın bu sınırları içerisinde; G-AgP hastalarında, enflamasyon esnasında artış gösteren TOS seviyesi cerrahi olmayan periodontal tedavi yapılarak düzenlenebilir.
Anahtar Kelime:

Konular: Tıbbi Araştırmalar Deneysel Diş Hekimliği

The effects of periodontal therapy on oxidant and antioxidant status in patients with aggressive periodontitis

Öz:
Aim: The aim of this study was to determine the effect of non-surgical periodontal therapy on gingival crevicular fluid (GCF), interleukin 1βeta (IL-β) and oxidant-antioxidant levels in patients with aggressive periodontitis. Materials and Method: Twenty-six subjects, including 14 generalized aggressive periodontitis (G-AgP) and 12 periodontally healthy non-smoker individuals were selected for the study. Probing pocket depth (PPD), clinical attachment level (CAL), gingival (GI) and plaque indices (PI), and bleeding on probing (BOP) were measured. To determine total oxidant status (TOS) and total antioxidant status (TAS) and IL-1β, GCF was drawn from each subject. The GCF and clinical measurements were recorded at baseline and 6 weeks after periodontal treatment. Conclusions: The study showed statistically significant improvement of clinical parameters after periodontal treatment. There was no significant difference in GCF IL-1β levels between the baseline and 6 weeks in the G-AgP patients group (p > 0.05). The TOS levels at 6 weeks of the G-AgP patients group were significantly lower than those at baseline (p < 0.05). Within the limitations of this study it can be concluded that GCF TOS level in G-AgP patients increased during the inflammation and can be restored by the non-surgical periodontal therapy.
Anahtar Kelime:

Konular: Tıbbi Araştırmalar Deneysel Diş Hekimliği
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA AKPINAR A, TOKER H, BOSTANCI V, POYRAZ Ö, Aydin H (2019). Agresif periodontitisli hastalarda periodontal tedavinin oksidan ve antioksidan seviyeleri üzerine etkisi. , 8 - 13. 10.5505/yeditepe.2019.63634
Chicago AKPINAR Aysun,TOKER HÜLYA,BOSTANCI Vildan,POYRAZ Ömer,Aydin Huseyin Agresif periodontitisli hastalarda periodontal tedavinin oksidan ve antioksidan seviyeleri üzerine etkisi. (2019): 8 - 13. 10.5505/yeditepe.2019.63634
MLA AKPINAR Aysun,TOKER HÜLYA,BOSTANCI Vildan,POYRAZ Ömer,Aydin Huseyin Agresif periodontitisli hastalarda periodontal tedavinin oksidan ve antioksidan seviyeleri üzerine etkisi. , 2019, ss.8 - 13. 10.5505/yeditepe.2019.63634
AMA AKPINAR A,TOKER H,BOSTANCI V,POYRAZ Ö,Aydin H Agresif periodontitisli hastalarda periodontal tedavinin oksidan ve antioksidan seviyeleri üzerine etkisi. . 2019; 8 - 13. 10.5505/yeditepe.2019.63634
Vancouver AKPINAR A,TOKER H,BOSTANCI V,POYRAZ Ö,Aydin H Agresif periodontitisli hastalarda periodontal tedavinin oksidan ve antioksidan seviyeleri üzerine etkisi. . 2019; 8 - 13. 10.5505/yeditepe.2019.63634
IEEE AKPINAR A,TOKER H,BOSTANCI V,POYRAZ Ö,Aydin H "Agresif periodontitisli hastalarda periodontal tedavinin oksidan ve antioksidan seviyeleri üzerine etkisi." , ss.8 - 13, 2019. 10.5505/yeditepe.2019.63634
ISNAD AKPINAR, Aysun vd. "Agresif periodontitisli hastalarda periodontal tedavinin oksidan ve antioksidan seviyeleri üzerine etkisi". (2019), 8-13. https://doi.org/10.5505/yeditepe.2019.63634
APA AKPINAR A, TOKER H, BOSTANCI V, POYRAZ Ö, Aydin H (2019). Agresif periodontitisli hastalarda periodontal tedavinin oksidan ve antioksidan seviyeleri üzerine etkisi. 7tepe Klinik, 15(1), 8 - 13. 10.5505/yeditepe.2019.63634
Chicago AKPINAR Aysun,TOKER HÜLYA,BOSTANCI Vildan,POYRAZ Ömer,Aydin Huseyin Agresif periodontitisli hastalarda periodontal tedavinin oksidan ve antioksidan seviyeleri üzerine etkisi. 7tepe Klinik 15, no.1 (2019): 8 - 13. 10.5505/yeditepe.2019.63634
MLA AKPINAR Aysun,TOKER HÜLYA,BOSTANCI Vildan,POYRAZ Ömer,Aydin Huseyin Agresif periodontitisli hastalarda periodontal tedavinin oksidan ve antioksidan seviyeleri üzerine etkisi. 7tepe Klinik, vol.15, no.1, 2019, ss.8 - 13. 10.5505/yeditepe.2019.63634
AMA AKPINAR A,TOKER H,BOSTANCI V,POYRAZ Ö,Aydin H Agresif periodontitisli hastalarda periodontal tedavinin oksidan ve antioksidan seviyeleri üzerine etkisi. 7tepe Klinik. 2019; 15(1): 8 - 13. 10.5505/yeditepe.2019.63634
Vancouver AKPINAR A,TOKER H,BOSTANCI V,POYRAZ Ö,Aydin H Agresif periodontitisli hastalarda periodontal tedavinin oksidan ve antioksidan seviyeleri üzerine etkisi. 7tepe Klinik. 2019; 15(1): 8 - 13. 10.5505/yeditepe.2019.63634
IEEE AKPINAR A,TOKER H,BOSTANCI V,POYRAZ Ö,Aydin H "Agresif periodontitisli hastalarda periodontal tedavinin oksidan ve antioksidan seviyeleri üzerine etkisi." 7tepe Klinik, 15, ss.8 - 13, 2019. 10.5505/yeditepe.2019.63634
ISNAD AKPINAR, Aysun vd. "Agresif periodontitisli hastalarda periodontal tedavinin oksidan ve antioksidan seviyeleri üzerine etkisi". 7tepe Klinik 15/1 (2019), 8-13. https://doi.org/10.5505/yeditepe.2019.63634