Is it possible that the pathogenesis of osteoarthritis could start with subchondral trabecular bone loss like osteoporosis?
Yıl: 2018 Cilt: 29 Sayı: 3 Sayfa Aralığı: 152 - 158 Metin Dili: İngilizce DOI: 10.5606/ehc.2018.007 İndeks Tarihi: 22-11-2019
Is it possible that the pathogenesis of osteoarthritis could start with subchondral trabecular bone loss like osteoporosis?
Öz: Objectives: This study aims to investigate the role of subchondral trabecular bone thickness in the mechanism of knee osteoarthritis and the correlation of osteoarthritis and osteoporosis pathogenesis. Patients and methods: The study included 62 patients (9 males, 53 females; mean age 66.7 years; range, 50 to 84 years) with osteoarthritis. All radiographs were evaluated according to Kellgren and Lawrence classification. The bone mineral density of the patients was measured and bone samples were collected from all patients included in the study during the surgical procedure and investigated pathologically. Results: Osteoarthritis grade and trabecular bone thickness were correlated with each other. Trabecular thickness rate was higher in patients with severe osteoarthritis, whereas trabecular thickness rate was statistically significantly lower than the mean in patients with mild osteoarthritis (p=0.045). Conclusion: Trabecular thickness rate was significantly lower in the mild grade of osteoarthritis compared to the severe grade. As the level of osteoarthritis increased, the number of patients with osteoporosis decreased.
Anahtar Kelime: Konular:
Osteoartrit patogenezi osteoporoza benzer şekilde subkondral trabeküler kemik kaybı ile başlıyor olabilir mi?
Öz: Amaç: Bu çalışmada, diz osteoartriti mekanizmasında subkondral trabeküler kemik kalınlığının rolü ve osteoartrit ile osteoporoz patogenezinin ilişkisi araştırıldı. Hastalar ve yöntemler: Çalışmaya osteoartritli 62 hasta (9 erkek, 53 kadın; ort. yaş 66.7 yıl; dağılım, 50-84 yıl) dahil edildi. Tüm radyografiler Kellgren ve Lawrence sınıflamasına göre değerlendirildi. Hastaların kemik mineral yoğunluğu ölçüldü ve cerrahi işlem sırasında çalışmaya dahil edilen tüm hastaların kemik örnekleri toplandı ve patolojik olarak incelendi. Bulgular: Osteoartrit evresi ve trabeküler kemik kalınlığı birbiriyle ilişkiliydi. Şiddetli osteoartritli hastalarda trabeküler kalınlık oranı daha yüksek iken hafif osteoartritli hastalarda trabeküler kalınlık oranı ortalamadan istatistiksel olarak anlamlı derecede düşük idi (p=0.045). Sonuç: Trabeküler kalınlık oranı osteoartritin hafif evresinde şiddetli evreye kıyasla anlamlı derecede daha düşük idi. Osteoartrit düzeyi arttıkça osteoporozlu hasta sayısı azaldı.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Tokgöz M, ATİK O, Esendagli Yilmaz G, Öğüt B, Bozkurt H (2018). Is it possible that the pathogenesis of osteoarthritis could start with subchondral trabecular bone loss like osteoporosis?. , 152 - 158. 10.5606/ehc.2018.007 |
| Chicago | Tokgöz Mehmet Ali,ATİK Osman Şahap,Esendagli Yilmaz Guldal,Öğüt Betül,Bozkurt Hasan Hüseyin Is it possible that the pathogenesis of osteoarthritis could start with subchondral trabecular bone loss like osteoporosis?. (2018): 152 - 158. 10.5606/ehc.2018.007 |
| MLA | Tokgöz Mehmet Ali,ATİK Osman Şahap,Esendagli Yilmaz Guldal,Öğüt Betül,Bozkurt Hasan Hüseyin Is it possible that the pathogenesis of osteoarthritis could start with subchondral trabecular bone loss like osteoporosis?. , 2018, ss.152 - 158. 10.5606/ehc.2018.007 |
| AMA | Tokgöz M,ATİK O,Esendagli Yilmaz G,Öğüt B,Bozkurt H Is it possible that the pathogenesis of osteoarthritis could start with subchondral trabecular bone loss like osteoporosis?. . 2018; 152 - 158. 10.5606/ehc.2018.007 |
| Vancouver | Tokgöz M,ATİK O,Esendagli Yilmaz G,Öğüt B,Bozkurt H Is it possible that the pathogenesis of osteoarthritis could start with subchondral trabecular bone loss like osteoporosis?. . 2018; 152 - 158. 10.5606/ehc.2018.007 |
| IEEE | Tokgöz M,ATİK O,Esendagli Yilmaz G,Öğüt B,Bozkurt H "Is it possible that the pathogenesis of osteoarthritis could start with subchondral trabecular bone loss like osteoporosis?." , ss.152 - 158, 2018. 10.5606/ehc.2018.007 |
| ISNAD | Tokgöz, Mehmet Ali vd. "Is it possible that the pathogenesis of osteoarthritis could start with subchondral trabecular bone loss like osteoporosis?". (2018), 152-158. https://doi.org/10.5606/ehc.2018.007 |
| APA | Tokgöz M, ATİK O, Esendagli Yilmaz G, Öğüt B, Bozkurt H (2018). Is it possible that the pathogenesis of osteoarthritis could start with subchondral trabecular bone loss like osteoporosis?. Eklem Hastalıkları ve Cerrahisi Dergisi (Eski Adı: Artroplasti Artroskopik Cerrahi Derg.), 29(3), 152 - 158. 10.5606/ehc.2018.007 |
| Chicago | Tokgöz Mehmet Ali,ATİK Osman Şahap,Esendagli Yilmaz Guldal,Öğüt Betül,Bozkurt Hasan Hüseyin Is it possible that the pathogenesis of osteoarthritis could start with subchondral trabecular bone loss like osteoporosis?. Eklem Hastalıkları ve Cerrahisi Dergisi (Eski Adı: Artroplasti Artroskopik Cerrahi Derg.) 29, no.3 (2018): 152 - 158. 10.5606/ehc.2018.007 |
| MLA | Tokgöz Mehmet Ali,ATİK Osman Şahap,Esendagli Yilmaz Guldal,Öğüt Betül,Bozkurt Hasan Hüseyin Is it possible that the pathogenesis of osteoarthritis could start with subchondral trabecular bone loss like osteoporosis?. Eklem Hastalıkları ve Cerrahisi Dergisi (Eski Adı: Artroplasti Artroskopik Cerrahi Derg.), vol.29, no.3, 2018, ss.152 - 158. 10.5606/ehc.2018.007 |
| AMA | Tokgöz M,ATİK O,Esendagli Yilmaz G,Öğüt B,Bozkurt H Is it possible that the pathogenesis of osteoarthritis could start with subchondral trabecular bone loss like osteoporosis?. Eklem Hastalıkları ve Cerrahisi Dergisi (Eski Adı: Artroplasti Artroskopik Cerrahi Derg.). 2018; 29(3): 152 - 158. 10.5606/ehc.2018.007 |
| Vancouver | Tokgöz M,ATİK O,Esendagli Yilmaz G,Öğüt B,Bozkurt H Is it possible that the pathogenesis of osteoarthritis could start with subchondral trabecular bone loss like osteoporosis?. Eklem Hastalıkları ve Cerrahisi Dergisi (Eski Adı: Artroplasti Artroskopik Cerrahi Derg.). 2018; 29(3): 152 - 158. 10.5606/ehc.2018.007 |
| IEEE | Tokgöz M,ATİK O,Esendagli Yilmaz G,Öğüt B,Bozkurt H "Is it possible that the pathogenesis of osteoarthritis could start with subchondral trabecular bone loss like osteoporosis?." Eklem Hastalıkları ve Cerrahisi Dergisi (Eski Adı: Artroplasti Artroskopik Cerrahi Derg.), 29, ss.152 - 158, 2018. 10.5606/ehc.2018.007 |
| ISNAD | Tokgöz, Mehmet Ali vd. "Is it possible that the pathogenesis of osteoarthritis could start with subchondral trabecular bone loss like osteoporosis?". Eklem Hastalıkları ve Cerrahisi Dergisi (Eski Adı: Artroplasti Artroskopik Cerrahi Derg.) 29/3 (2018), 152-158. https://doi.org/10.5606/ehc.2018.007 |
