Santral Retinal Ven Tıkanıklığı ile Maküla Ödeminde Genetik ve Risk Faktörleri

Fahrettin AKAY, (İzmir Katip Çelebi Üniversitesi)
Muhammed Altınışık, (Manisa Celal Bayar Üniversitesi)
Yusuf Ziya GÜVEN (İzmir Katip Çelebi Üniversitesi)
Güncel Retina Dergisi
3 0
Yıl: 2019 Cilt: 3 Sayı: 1 Sayfa Aralığı: 6 - 10 Metin Dili: Türkçe İndeks Tarihi: 28-11-2019

Santral Retinal Ven Tıkanıklığı ile Maküla Ödeminde Genetik ve Risk Faktörleri

Öz:
Retinal venöz tıkanıklıklar retinanın vasküler hastalıkları içinde diyabetik retinopatiden sonra en fazla görülen körlüksebebidir. Yaş ilerledikçe görülme oranı artar. Bu hastalığa zemin hazırlayan sistemik, genetik ve oküler risk faktörlerimevcuttur. Metiltetrahidrofolat redüktaz (MTHFR) enzim gen mutasyonu (MTHFR C677T) ile homosisteinin plazmadüzeylerindeki artış tromboza eğilimi arttırır. Faktör V Leiden polimorfizmi FVR506Q, protrombin (FII)G20210A mutasyonu,anjiyotensin dönüştürücü enzim (ACE), ins287del ve anjiyotensinojen (AGT) T235M mutasyonları diğer sık bilinen genmutasyonlarındandır. Sistemik risk faktörleri hipertansiyon, hiperlipidemi, sigara kullanımı, diabetes mellitus ve obezite gibiateroskleroza zemin hazırlayan hastalıklardan oluşmaktadır. Glokom, orbital inflamasyon ve kitleler, glob travması oküler riskfaktörlerini oluşturmaktadır.
Anahtar Kelime:

Konular: Cerrahi

Genetic and Risk Factors in Central Retinal Venous Occlusion with Macular Edema

Öz:
Retinal venous occlusions are the most common cause of blindness after diabetic retinopathy. Incidence of the disease increases with the age. There are systemic, genetic, and ocular risk factors that set the backround of disease. Methyltetrahydrofolate reductase (MTHFR) enzyme gene mutation (MTHFR C677T) increases the plasma levels of homocysteine and the thrombosis tendency. Factor V Leiden polymorphism FVR506Q, prothrombin (FII) G20210A, angiotensin converting enzyme (ACE) ins287del and angiotensinogen (AGT) T235M are other common gene mutations for thromboembolic events. Systemic risk factors such as hypertension, hyperlipidemia, cigarette smoking, diabetes mellitus and obesity are the diseases which make atherosclerosis. Other ocular risk factors are glaucoma, orbital masses with inflammation and glob trauma.
Anahtar Kelime:

Konular: Cerrahi
Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Bibliyografik
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APA Akay F, Altinisik M, Güven Y (2019). Santral Retinal Ven Tıkanıklığı ile Maküla Ödeminde Genetik ve Risk Faktörleri. , 6 - 10.
Chicago Akay Fahrettin,Altinisik Muhammed,Güven Yusuf Ziya Santral Retinal Ven Tıkanıklığı ile Maküla Ödeminde Genetik ve Risk Faktörleri. (2019): 6 - 10.
MLA Akay Fahrettin,Altinisik Muhammed,Güven Yusuf Ziya Santral Retinal Ven Tıkanıklığı ile Maküla Ödeminde Genetik ve Risk Faktörleri. , 2019, ss.6 - 10.
AMA Akay F,Altinisik M,Güven Y Santral Retinal Ven Tıkanıklığı ile Maküla Ödeminde Genetik ve Risk Faktörleri. . 2019; 6 - 10.
Vancouver Akay F,Altinisik M,Güven Y Santral Retinal Ven Tıkanıklığı ile Maküla Ödeminde Genetik ve Risk Faktörleri. . 2019; 6 - 10.
IEEE Akay F,Altinisik M,Güven Y "Santral Retinal Ven Tıkanıklığı ile Maküla Ödeminde Genetik ve Risk Faktörleri." , ss.6 - 10, 2019.
ISNAD Akay, Fahrettin vd. "Santral Retinal Ven Tıkanıklığı ile Maküla Ödeminde Genetik ve Risk Faktörleri". (2019), 6-10.
APA Akay F, Altinisik M, Güven Y (2019). Santral Retinal Ven Tıkanıklığı ile Maküla Ödeminde Genetik ve Risk Faktörleri. Güncel Retina Dergisi, 3(1), 6 - 10.
Chicago Akay Fahrettin,Altinisik Muhammed,Güven Yusuf Ziya Santral Retinal Ven Tıkanıklığı ile Maküla Ödeminde Genetik ve Risk Faktörleri. Güncel Retina Dergisi 3, no.1 (2019): 6 - 10.
MLA Akay Fahrettin,Altinisik Muhammed,Güven Yusuf Ziya Santral Retinal Ven Tıkanıklığı ile Maküla Ödeminde Genetik ve Risk Faktörleri. Güncel Retina Dergisi, vol.3, no.1, 2019, ss.6 - 10.
AMA Akay F,Altinisik M,Güven Y Santral Retinal Ven Tıkanıklığı ile Maküla Ödeminde Genetik ve Risk Faktörleri. Güncel Retina Dergisi. 2019; 3(1): 6 - 10.
Vancouver Akay F,Altinisik M,Güven Y Santral Retinal Ven Tıkanıklığı ile Maküla Ödeminde Genetik ve Risk Faktörleri. Güncel Retina Dergisi. 2019; 3(1): 6 - 10.
IEEE Akay F,Altinisik M,Güven Y "Santral Retinal Ven Tıkanıklığı ile Maküla Ödeminde Genetik ve Risk Faktörleri." Güncel Retina Dergisi, 3, ss.6 - 10, 2019.
ISNAD Akay, Fahrettin vd. "Santral Retinal Ven Tıkanıklığı ile Maküla Ödeminde Genetik ve Risk Faktörleri". Güncel Retina Dergisi 3/1 (2019), 6-10.
Sayfa Oluşturulma Tarihi
23-04-2024 9:25

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