C-reactive protein and red cell distribution width as indicators of complications in patients with acute appendicitis
Yıl: 2019 Cilt: 4 Sayı: 2 Sayfa Aralığı: 76 - 80 Metin Dili: İngilizce DOI: 10.25000/acem.546308 İndeks Tarihi: 22-01-2020
C-reactive protein and red cell distribution width as indicators of complications in patients with acute appendicitis
Öz: Aim: Acute appendicitis is one of the most common operations in general surgery. When complicated, mortality and morbidity increases. We aimed to find out whether use of C-reactive protein (CRP) and red cell distribution width (RDW) may help to find out development of complications with acute appendicitis at initial evaluation in an emergency department. Methods: Files of the patients who underwent operations for acute appendicitis between January 2017 and August 2017 were reviewed. Development of complications was recorded and the patients were grouped as with and without complications and were compared about age, sex RDW, CRP, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels. Diagnostic efficiency of CRP and RDW on the development of complications in acute appendicitis was investigated with regression analysis and by receiver operator characteristic curve analysis. Results: Age, CRP and RDW were found to be significantly related to perforation (p<0.001 for all) (Bonferoni correction), while white blood cell (WBC), AST and ALT were found to be insignificant (p=0.052, p=0.806 and p=0.804, respectively. There was a significant correlation between RDW and CRP in the Spearman non-parametric correlation analysis (correlation coefficient r=0.244 and p<0.001). There was no significant correlation of WBC to CRP and RDW. Conclusion: CRP and RDW are biochemical parameters that help us to identify the development of complications in acute appencitis. CRP may be elevated in acute appendicitis; however, it must be kept in mind to be cautious about a potentially complicated acute appendicitis after a certain level, RDW in our study has been found to be elevated in complicated appendicitis cases; but, it may not helpful to detect for perforated or gangrenous appendicitis.
Anahtar Kelime: Konular:
Akut apandisit tanısı konmuş hastalarda komplikasyon belirteçleri olarak C-reaktif protein ve kırmızı küre dağılım indisinin yeri ve önemi
Öz: Amaç: Akut apandisit genel cerrahide en sık karşılaşılan operasyon sebeplerinden biridir. Komplike olduğu zaman mortalite ve morbidite artmaktadır. C-reaktif protein (CRP) ve kırmızı küre genişlik dağılım indisi (RDW) değerlerinin kullanılmasının komplike olan akut apandisit vakalarını acil servisteki ilk muayenede ayırt etmemizde faydalı olup olmadığını incelemeyi amaçladık. Yöntemler: Ocak 2017 ve Ağustos 2017 tarihleri arasında akut apandisit nedeniyle opere edilmiş olan hastaların dosyaları tarandı. Hastalar yaş, cinsiyet, CRP, RDW, alanin aminotransferaz, aspartat aminotransferaz değerleri açısından komplike olan ve olmayan akut apandisit vakalarında karşılaştırıldı. Artmış serum CRP ve RDW değerlerinin komplike apandisit tanısı koymada ne kadar etkin olduğu regresyon analizi ve alıcı işlemci nitelikleri eğrisi analizi ile değerlendirildi. Bulgular: Yaş, RDW ve CRP, perforasyon ve gangrenöz apandisit ile belirgin olarak ilişkili olarak bulundu, p<0,001, beyaz küre, aspartat aminotransferaz (AST), alanin aminotransferaz (ALT) düzeyleri ise P değerleri açısından anlamsız olarak bulundu (sırasıyla p=0,052, p=0,806 ve p=0,804). RDW ile CRP arasında korelasyon olmakla birlikte (korelasyon katsayısı r=0,244 ve p<0,001), beyaz küre ile RDW ve CRP arasında anlamlı bir ilişki yoktu. Sonuç: CRP ve RDW komplike apandisit tanısını koymamızda biyokimyasal parametreler olarak değerlendirilmelidir. CRP akut apandisit vakalarında artmış olarak tespit edilebilir ancak belli bir seviyeden sonra komplike olmuş bir apandisite işaret edebilir. RDW bizim çalışmamızda komplike apandisitlerde artmış olarak bulundu. Ancak bu yükseklik için bir eşik değer tespit edilemedi.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Akturk O, Cakir M, Yildirim D, Akinci M (2019). C-reactive protein and red cell distribution width as indicators of complications in patients with acute appendicitis. , 76 - 80. 10.25000/acem.546308 |
| Chicago | Akturk Okan Murat,Cakir Mikail,Yildirim Dogan,Akinci Muzaffer C-reactive protein and red cell distribution width as indicators of complications in patients with acute appendicitis. (2019): 76 - 80. 10.25000/acem.546308 |
| MLA | Akturk Okan Murat,Cakir Mikail,Yildirim Dogan,Akinci Muzaffer C-reactive protein and red cell distribution width as indicators of complications in patients with acute appendicitis. , 2019, ss.76 - 80. 10.25000/acem.546308 |
| AMA | Akturk O,Cakir M,Yildirim D,Akinci M C-reactive protein and red cell distribution width as indicators of complications in patients with acute appendicitis. . 2019; 76 - 80. 10.25000/acem.546308 |
| Vancouver | Akturk O,Cakir M,Yildirim D,Akinci M C-reactive protein and red cell distribution width as indicators of complications in patients with acute appendicitis. . 2019; 76 - 80. 10.25000/acem.546308 |
| IEEE | Akturk O,Cakir M,Yildirim D,Akinci M "C-reactive protein and red cell distribution width as indicators of complications in patients with acute appendicitis." , ss.76 - 80, 2019. 10.25000/acem.546308 |
| ISNAD | Akturk, Okan Murat vd. "C-reactive protein and red cell distribution width as indicators of complications in patients with acute appendicitis". (2019), 76-80. https://doi.org/10.25000/acem.546308 |
| APA | Akturk O, Cakir M, Yildirim D, Akinci M (2019). C-reactive protein and red cell distribution width as indicators of complications in patients with acute appendicitis. Archives of Clinical and Experimental Medicine, 4(2), 76 - 80. 10.25000/acem.546308 |
| Chicago | Akturk Okan Murat,Cakir Mikail,Yildirim Dogan,Akinci Muzaffer C-reactive protein and red cell distribution width as indicators of complications in patients with acute appendicitis. Archives of Clinical and Experimental Medicine 4, no.2 (2019): 76 - 80. 10.25000/acem.546308 |
| MLA | Akturk Okan Murat,Cakir Mikail,Yildirim Dogan,Akinci Muzaffer C-reactive protein and red cell distribution width as indicators of complications in patients with acute appendicitis. Archives of Clinical and Experimental Medicine, vol.4, no.2, 2019, ss.76 - 80. 10.25000/acem.546308 |
| AMA | Akturk O,Cakir M,Yildirim D,Akinci M C-reactive protein and red cell distribution width as indicators of complications in patients with acute appendicitis. Archives of Clinical and Experimental Medicine. 2019; 4(2): 76 - 80. 10.25000/acem.546308 |
| Vancouver | Akturk O,Cakir M,Yildirim D,Akinci M C-reactive protein and red cell distribution width as indicators of complications in patients with acute appendicitis. Archives of Clinical and Experimental Medicine. 2019; 4(2): 76 - 80. 10.25000/acem.546308 |
| IEEE | Akturk O,Cakir M,Yildirim D,Akinci M "C-reactive protein and red cell distribution width as indicators of complications in patients with acute appendicitis." Archives of Clinical and Experimental Medicine, 4, ss.76 - 80, 2019. 10.25000/acem.546308 |
| ISNAD | Akturk, Okan Murat vd. "C-reactive protein and red cell distribution width as indicators of complications in patients with acute appendicitis". Archives of Clinical and Experimental Medicine 4/2 (2019), 76-80. https://doi.org/10.25000/acem.546308 |
