TY - JOUR TI - Reducing the Impact of Cutaneous Leishmaniasis Disease by Domestic Animals and Tilapia Fish: A System Dynamics Model AB - The purpose of this paper is to seek ways in reducing incidence of vector borne disease calledleishmaniasis on humans. Frequently encountered in East Mediterranean and SoutheasternAnatolian region of Turkey due to risk factors including poverty, malnutrition, lack of sanitationand defrostration, leishmaniasis disease is transmitted by sandflies’ (vector) bites to humans. Inaddition to the zooprophylaxis effect in which domestic animals acting as dead-end hosts are usedto alleviate the incidence on humans, we also incorporate the Tilapia fish population into themodel to observe its effect in terms of relieving the vector bites on humans. We elaborate dynamicbehavior and feedback loop structure of the system under study with three blood meal hosts:rodents, humans, and domestic animals. Proposed model is simulated throughout a period of 1000days. We conduct sensitivity analysis by changing the rates of vector biting and the number oflarvae eaten by Tilapia fish which influence the transmission of the disease. Results indicate thatbasic reproductive number 𝑅0 and its prevalence in humans decreases as the size of domesticanimal and the sandflies larvae eaten by Tilapia fish increases. AU - KURT, Seyma AU - Kesen, Saadettin PY - 2019 JO - Gazi University Journal of Science VL - 32 IS - 2 SN - 2147-1762 SP - 595 EP - 606 DB - TRDizin UR - http://search/yayin/detay/324492 ER -