Chemical Diversity and Biological Potential of Tanacetum praeteritum subsp. praeteritum Essential Oils

Gülmira ÖZEK (Anadolu Üniversitesi)
Journal of the Turkish Chemical Society, Section A: Chemistry
4 0
Yıl: 2018 Cilt: 5 Sayı: 2 Sayfa Aralığı: 493 - 510 Metin Dili: İngilizce DOI: 10.18596/jotcsa.389075 İndeks Tarihi: 22-02-2020

Chemical Diversity and Biological Potential of Tanacetum praeteritum subsp. praeteritum Essential Oils

Öz:
Two samples of Tanacetum praeteritum (Horwood) Heywood subsp. praeteritum(Horwood) were collected in flowering period and subjected separately to hydrodistillation toyield the essential oils (A and B). The oils were investigated for chemical composition with GCFIDand GC/MS techniques and evaluated against acetylcholinesterase and -amylase enzymesand free radicals (DPPH• and ABTS•+) using microtiter plate assays. Both oils were characterizedwith high abundance of oxygenated monoterpenes. The oils were distinguished by the mainconstituents, namely, camphor (37.6%), 1,8-cineole (19.5%) and terpinen-4-ol (9.3%) werefound as the major constituents in the oil A, while -thujone (79.4%) and -thujone (8.5%)were detected in the oil B. The oils demonstrated significant inhibitory (80% and 60.0%)potentials on acetylcholinesterase (an IC50 of 0.74 mg/mL and an IC50 of 1.78 mg/mL,respectively) which is involved in Alzheimer’s disease. With respect to antidiabetic activity, theoils demonstrated significant inhibiting potential on porcine pancreatic -amylase (an IC50 of1.02 mg/mL and an IC50 of 0.89 mg/mL) in I2/KI assay. The oils demonstrated weak free radicalscavenging activity against DPPH radicals and moderate activity (0.23 mM and 0.15 mM) againstABTS+• in TEAC assay.
Anahtar Kelime:

Konular: Kimya, Analitik Termodinamik Spektroskopi Kimya, Uygulamalı Kimya, Organik Kimya, Tıbbi Fizikokimya Kimya, İnorganik ve Nükleer
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA ÖZEK G (2018). Chemical Diversity and Biological Potential of Tanacetum praeteritum subsp. praeteritum Essential Oils. , 493 - 510. 10.18596/jotcsa.389075
Chicago ÖZEK Gülmira Chemical Diversity and Biological Potential of Tanacetum praeteritum subsp. praeteritum Essential Oils. (2018): 493 - 510. 10.18596/jotcsa.389075
MLA ÖZEK Gülmira Chemical Diversity and Biological Potential of Tanacetum praeteritum subsp. praeteritum Essential Oils. , 2018, ss.493 - 510. 10.18596/jotcsa.389075
AMA ÖZEK G Chemical Diversity and Biological Potential of Tanacetum praeteritum subsp. praeteritum Essential Oils. . 2018; 493 - 510. 10.18596/jotcsa.389075
Vancouver ÖZEK G Chemical Diversity and Biological Potential of Tanacetum praeteritum subsp. praeteritum Essential Oils. . 2018; 493 - 510. 10.18596/jotcsa.389075
IEEE ÖZEK G "Chemical Diversity and Biological Potential of Tanacetum praeteritum subsp. praeteritum Essential Oils." , ss.493 - 510, 2018. 10.18596/jotcsa.389075
ISNAD ÖZEK, Gülmira. "Chemical Diversity and Biological Potential of Tanacetum praeteritum subsp. praeteritum Essential Oils". (2018), 493-510. https://doi.org/10.18596/jotcsa.389075
APA ÖZEK G (2018). Chemical Diversity and Biological Potential of Tanacetum praeteritum subsp. praeteritum Essential Oils. Journal of the Turkish Chemical Society, Section A: Chemistry, 5(2), 493 - 510. 10.18596/jotcsa.389075
Chicago ÖZEK Gülmira Chemical Diversity and Biological Potential of Tanacetum praeteritum subsp. praeteritum Essential Oils. Journal of the Turkish Chemical Society, Section A: Chemistry 5, no.2 (2018): 493 - 510. 10.18596/jotcsa.389075
MLA ÖZEK Gülmira Chemical Diversity and Biological Potential of Tanacetum praeteritum subsp. praeteritum Essential Oils. Journal of the Turkish Chemical Society, Section A: Chemistry, vol.5, no.2, 2018, ss.493 - 510. 10.18596/jotcsa.389075
AMA ÖZEK G Chemical Diversity and Biological Potential of Tanacetum praeteritum subsp. praeteritum Essential Oils. Journal of the Turkish Chemical Society, Section A: Chemistry. 2018; 5(2): 493 - 510. 10.18596/jotcsa.389075
Vancouver ÖZEK G Chemical Diversity and Biological Potential of Tanacetum praeteritum subsp. praeteritum Essential Oils. Journal of the Turkish Chemical Society, Section A: Chemistry. 2018; 5(2): 493 - 510. 10.18596/jotcsa.389075
IEEE ÖZEK G "Chemical Diversity and Biological Potential of Tanacetum praeteritum subsp. praeteritum Essential Oils." Journal of the Turkish Chemical Society, Section A: Chemistry, 5, ss.493 - 510, 2018. 10.18596/jotcsa.389075
ISNAD ÖZEK, Gülmira. "Chemical Diversity and Biological Potential of Tanacetum praeteritum subsp. praeteritum Essential Oils". Journal of the Turkish Chemical Society, Section A: Chemistry 5/2 (2018), 493-510. https://doi.org/10.18596/jotcsa.389075
Sayfa Oluşturulma Tarihi
02-05-2024 13:37

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