TY  - JOUR
TI  - Therapeutic plasmapheresis: an eleven-year clinical experience
AB  - Objective: Therapeutic plasma exchange (TPE) is currently indicated as an alternative treatment regimen in anumber of guidelines for various medical conditions. In this article we retrospectively reviewed cases whounderwent TPE in Bakırköy Dr. Sadi Konuk Training and Research Hospital intensive care unit between 2007and 2016 and compared the findings to the current reports in the literature.Methods: A total of 80 cases were treated with TPE between 2007 and 2016 in our intensive care unit.Information on demographic variables, therapeutic indications, catheterized veins, complications during theprocedure, number of sessions, replacement products used and survival data was collected. In addition, preandpost-procedure serum triglyceride, cholesterol and amylase levels were also collected in acute pancreatitiscases associated with hypertriglyceridemia.Results: A total of 501 TPE sessions were performed on 80 cases comprising 35 neurology, 18 hematology,12 hypertriglycemic acute pancreatitis and 7 acute hepatic insufficiency patients, along with 8 cases with lesscommon indications including sepsis, hyperthyroidism resistant to medical therapy and toxic epidermalnecrolysis. The age of the subjects ranged between 12 and 82 years (mean; 45.08 ± 14.67 years). Sixteen(23.19%) cases died before the completion of the planned sessions. Pre- and post-procedure serum triglyceride,cholesterol and amylase levels were significantly different in acute pancreatitis cases (p < 0.05).Conclusion: Timely implementation of TPE in applicable indications may be helpful in preventing morbidityand mortality in a wide spectrum of disorders.
AU  - HERGÜNSEL, Gülsüm Oya
AU  - TEKDÖŞ ŞEKER, Yasemin
AU  - ÖZEL BİLGİ, Deniz
DO  - 10.18621/eurj.356552
PY  - 2018
JO  - The European Research Journal
VL  - 4
IS  - 4
SN  - 2149-3189
SP  - 343
EP  - 348
DB  - TRDizin
UR  - http://search/yayin/detay/325327
ER  -