Purpose: This study was conducted regarding the internship program that had been applied for the first time in nursing curriculum and the objective of it was to determine opinions of the nurses that were working in a clinic in which internship program with 4th class students had been applied for the first time. Materials and methods: This descriptive study was conducted with 101 nursing students that were studying in the 4th class with internship program and 100 nurses working in clinics that this internship program applied. Data was collected with internship program evaluation form that was developed by researchers based on the literature. This form was developed for both students and nurses individually. The evaluation of data was made by using descriptive tests. Results: 96.4% of students stated that internship program supported them in learning nursing occupation and adaptation. Also students informed that the internship program supported them in developing their hand skills (89.3%), responsibility and communication skills (82.1%), learning team work and increasing self-confidence (81%). On the other hand, nurses that worked with these students stated that internship program supported students in developing their hand skills (97.9%), increasing their theoretical knowledge (91.8%), learning the occupation and adaptation (93.8%), learning the team work (91.8%) and increasing their self-confidence (93.8%). 72.6% of students and 98% of nurses wanted internship program to be continued.phosphatase levels were lower and glutathione levels, myeloperoxidase activity, and superoxide dismutase activity were similar between Leflunomide treated and untreated Methotrexate toxicity groups. Conclusion:Structuring the internship program, which supports developing occupational skills of students in nursing education, by getting feedbacks of students and clinic nurses is important to make it more effective and efficient.