L-Carnitine Treatment In Acute Valproic Acid Intoxication: Case Report
Yıl: 2019 Cilt: 10 Sayı: 3 Sayfa Aralığı: 96 - 98 Metin Dili: İngilizce DOI: 10.33381/dcbybd.2019.2037 İndeks Tarihi: 25-03-2020
L-Carnitine Treatment In Acute Valproic Acid Intoxication: Case Report
Öz: Valproic acid (VPA) is a widely used drug with various indications (psychiatric disorders, epilepsy, migraineetc.) and it has been used in many cases of suicide attempts. VPA intoxication may cause electrolyte imbalances,hepatotoxicity, pancreatitis, bone marrow suppression, and brain edema. The most common finding in VPAintoxication is coma and respiratory depression as a result of central nervous system suppression. Case reportsemphasize that the efficacy of L-carnitine and various extracorporeal elimination techniques like intermittenthemodialysis or continuous renal replacement therapies in the treatment of VPA intoxication. In this report wepresent the case of a 34 year old female with VPA intoxication who was successfully treated with L-carnitine.
Anahtar Kelime: Konular:
Akut Valproik Asit İntoksikasyonunda L-Karnitin Tedavisi: Olgu Sunumu
Öz: Valproik asit (VPA) çeşitli endikasyonlarla (psikiyatrik bozukluklar, epilepsi, migren vb.) yaygın olarak kullanılan bir ilaçtır ve birçok intihar girişimi vakasında kullanılmıştır. VPA intoksikasyonu elektrolit bozukluklarına, hepatotoksisiteye, pankreatit, kemik iliği baskılanması ve beyin ödemine neden olabilir. VPA intoksikasyonunda en sık rastlanan bulgular, merkezi sinir sistemi baskılanmasının bir sonucu olarak koma ve solunum depresyonudur. Vaka raporları, L-karnitinin; intermittan hemodiyaliz veya sürekli renal replasman tedavileri gibi çeşitli ekstrakorporeal eliminasyon tekniklerinin VPA intoksikasyonu tedavisindeki etkinliğini vurgulamaktadır. Bu yazıda, L-karnitin ile başarılı bir şekilde tedavi edilen VPA toksisitesi olan 34 yaşında bir kadın olguyu sunmayı amaçladık.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık
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| APA | ÖZER D, YILDIRIM V, AYYILDIZ A, karakoç e, YELKEN B (2019). L-Carnitine Treatment In Acute Valproic Acid Intoxication: Case Report. , 96 - 98. 10.33381/dcbybd.2019.2037 |
| Chicago | ÖZER Demet,YILDIRIM Volkan,AYYILDIZ AYŞE,karakoç ebru,YELKEN Birgül L-Carnitine Treatment In Acute Valproic Acid Intoxication: Case Report. (2019): 96 - 98. 10.33381/dcbybd.2019.2037 |
| MLA | ÖZER Demet,YILDIRIM Volkan,AYYILDIZ AYŞE,karakoç ebru,YELKEN Birgül L-Carnitine Treatment In Acute Valproic Acid Intoxication: Case Report. , 2019, ss.96 - 98. 10.33381/dcbybd.2019.2037 |
| AMA | ÖZER D,YILDIRIM V,AYYILDIZ A,karakoç e,YELKEN B L-Carnitine Treatment In Acute Valproic Acid Intoxication: Case Report. . 2019; 96 - 98. 10.33381/dcbybd.2019.2037 |
| Vancouver | ÖZER D,YILDIRIM V,AYYILDIZ A,karakoç e,YELKEN B L-Carnitine Treatment In Acute Valproic Acid Intoxication: Case Report. . 2019; 96 - 98. 10.33381/dcbybd.2019.2037 |
| IEEE | ÖZER D,YILDIRIM V,AYYILDIZ A,karakoç e,YELKEN B "L-Carnitine Treatment In Acute Valproic Acid Intoxication: Case Report." , ss.96 - 98, 2019. 10.33381/dcbybd.2019.2037 |
| ISNAD | ÖZER, Demet vd. "L-Carnitine Treatment In Acute Valproic Acid Intoxication: Case Report". (2019), 96-98. https://doi.org/10.33381/dcbybd.2019.2037 |
| APA | ÖZER D, YILDIRIM V, AYYILDIZ A, karakoç e, YELKEN B (2019). L-Carnitine Treatment In Acute Valproic Acid Intoxication: Case Report. Dahili ve Cerrahi Bilimler Yoğun Bakım Dergisi, 10(3), 96 - 98. 10.33381/dcbybd.2019.2037 |
| Chicago | ÖZER Demet,YILDIRIM Volkan,AYYILDIZ AYŞE,karakoç ebru,YELKEN Birgül L-Carnitine Treatment In Acute Valproic Acid Intoxication: Case Report. Dahili ve Cerrahi Bilimler Yoğun Bakım Dergisi 10, no.3 (2019): 96 - 98. 10.33381/dcbybd.2019.2037 |
| MLA | ÖZER Demet,YILDIRIM Volkan,AYYILDIZ AYŞE,karakoç ebru,YELKEN Birgül L-Carnitine Treatment In Acute Valproic Acid Intoxication: Case Report. Dahili ve Cerrahi Bilimler Yoğun Bakım Dergisi, vol.10, no.3, 2019, ss.96 - 98. 10.33381/dcbybd.2019.2037 |
| AMA | ÖZER D,YILDIRIM V,AYYILDIZ A,karakoç e,YELKEN B L-Carnitine Treatment In Acute Valproic Acid Intoxication: Case Report. Dahili ve Cerrahi Bilimler Yoğun Bakım Dergisi. 2019; 10(3): 96 - 98. 10.33381/dcbybd.2019.2037 |
| Vancouver | ÖZER D,YILDIRIM V,AYYILDIZ A,karakoç e,YELKEN B L-Carnitine Treatment In Acute Valproic Acid Intoxication: Case Report. Dahili ve Cerrahi Bilimler Yoğun Bakım Dergisi. 2019; 10(3): 96 - 98. 10.33381/dcbybd.2019.2037 |
| IEEE | ÖZER D,YILDIRIM V,AYYILDIZ A,karakoç e,YELKEN B "L-Carnitine Treatment In Acute Valproic Acid Intoxication: Case Report." Dahili ve Cerrahi Bilimler Yoğun Bakım Dergisi, 10, ss.96 - 98, 2019. 10.33381/dcbybd.2019.2037 |
| ISNAD | ÖZER, Demet vd. "L-Carnitine Treatment In Acute Valproic Acid Intoxication: Case Report". Dahili ve Cerrahi Bilimler Yoğun Bakım Dergisi 10/3 (2019), 96-98. https://doi.org/10.33381/dcbybd.2019.2037 |
