TY  - JOUR
TI  - Comparison of the Effects of Lidocaine and Dexmedetomidine Before Propofol Induction During Laryngeal Mask Airway Insertion
AB  - Objective: Laryngeal mask (LMA) is an airway device that can be used as an alternative to face mask and tracheal intubation. Different drug combinations can beused to ensure suitable conditions during LMA insertion. Lidocaine and dexmedetomidine are drugs that can be used to reduce hemodynamic response and suppressoropharyngeal reflexes during both intubation and LMA insertion. The aim of this study was to investigate the effects of lidocaine and dexmedetomidine on LMAinsertion.Methods: Sixty patients who were scheduled to undergo cystoscopy under general anesthesia with LMA were included in the study. Patients were randomly dividedinto two groups: Group L (those who received 1.5 mg/kg lidocaine) and Group D (those who received 1 μg/kg dexmedetomidine). Number of attempts of LMA insertion,ease of LMA insertion, mouth opening, laryngospasm, gumming, stomach distention, limb movements and spontaneous breathing and hemodynamic parameterswere recorded.Results: There was no statistically significant difference between the two groups in terms of the number of attempts of LMA insertion. In the first attempt, the LMAinsertion success rate was 70% for Group L and 73.3% for Group D. There was no statistically significant difference between the two groups in terms of mouth opening,laryngospasm, ease of LMA insertion, gumming, stomach distension, limb movement and spontaneous breathing. Systolic blood pressure, diastolic blood pressure,mean blood pressure and heart rate were statistically lower in Group D after drug administration. It was determined that the decreases in the other times werestatistically significant compared to the baseline values after drug administration in both groups.Conclusion: Based on the results of the present study, 1 μg/kg dexmedetomidine and 1.5 mg/kg lidocaine used before propofol induction provided similar conditionsfor LMA insertion. Dexmedetomidine has a more hypotensive effect and provides a greater reduction in heart rate than lidocaine. Furthermore, the use of lidocainebefore propofol induction provides better hemodynamic control than dexmedetomidine.
AU  - KİTAPÇIOĞLU, Dilek
AU  - KAVAKLİ, Ali Sait
DO  - 10.4274/eamr.galenos.2018.48344
PY  - 2019
JO  - European Archives of Medical Research
VL  - 35
IS  - 4
SN  - 2651-3137
SP  - 205
EP  - 210
DB  - TRDizin
UR  - http://search/yayin/detay/331006
ER  -