Perinatal and Medical Risk Factors in Children with Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder or Specific Learning Disorder: Comparison Between Diagnostic Groups
Yıl: 2019 Cilt: 20 Sayı: 6 Sayfa Aralığı: 502 - 507 Metin Dili: İngilizce DOI: 10.4274/imj.galenos.2019.02347 İndeks Tarihi: 21-04-2020
Perinatal and Medical Risk Factors in Children with Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder or Specific Learning Disorder: Comparison Between Diagnostic Groups
Öz: Introduction: Epigenetic changes in the pathogenesis ofneurodevelopmental disorders, including prenatal and earlylife exposures, are becoming as appealing as hereditarygenes. This study aimed to investigate possible pre-pubertalenvironmental and developmental risk factors for childrenwith Attention Deficit Hyperactivity Disorder (ADHD), AutismSpectrum Disorder (ASD), and Specific Learning Disorder (SLD).Methods: The study included 98 children (24 ADHD, 24 SLD,26 ASD, 20 controls) aged 7-12 years. The diagnostic evaluationwas based on the American Psychiatric Association Diagnosticand Statistical Manual of Mental Disorders and Schedule forAffective Disorders and Schizophrenia for School-age Childrenpresentversion. Parents completed socio-demographic dataform for clinical evaluation, and The Wechsler Children’sIntelligence scale was used to assess cognitive skills.Results: In our study, low parental education level, parentalunemployment, low-income, and history of psychiatricdisorders in first-degree relatives were associated with SLDrisk, prematurity, and early self-regulation difficulties wereassociated with ASD risk, and history of allergy was associatedwith ADHD risk.Conclusion: In this study, the presence of many differentrisk factors that play a possible role in neurodevelopmentaldisorders suggests that further epigenetic studies are needed.
Anahtar Kelime: Konular:
Dikkat Eksikliği Hiperaktivite Bozukluğu, Otizm Spektrum Bozukluğu veya Özgül Öğrenme Bozukluğu Olan Çocuklarda Perinatal ve Tıbbi Risk Faktörleri: Tanı Grupları Arası Karşılaştırma
Öz: Amaç: Nörogelişimsel bozuklukların patogenezinde doğum öncesi ve erken yaşam dönemi maruziyetlerini içeren epigenetik değişiklikler, kalıtsal genler kadar ilgi çekici olmaya başlamaktadır. Bu çalışmada puberte öncesi dönemde dikkat eksikliği hiperaktivite bozukluğu (DEHB), otizm spektrum bozukluğu (OSB) ve özgül öğrenme bozukluğu (ÖÖB) tanılı çocuklar için olası çevresel ve gelişimsel risk faktörlerinin araştırılması amaçlanmıştır. Yöntemler: Çalışmaya 7-12 yaş aralığında 98 çocuk (24 DEHB, 24 ÖÖB, 26 OSB, 24 kontrol) alınmıştır. Tanısal değerlendirmede Amerikan Psikiyatri Birliği Ruhsal Bozuklukların Tanısal ve Sayımsal El Kitabına dayalı görüşme, Okul Çağı Çocukları için Duygulanım Bozuklukları ve Şizofreni Görüşme Çizelgesi-şimdi versiyonu kullanılmıştır. Klinik değerlendirmede ebeveynler tarafından sosyo-demografik veri formu doldurulmuştur ve bilişsel değerlendirmede Wechsler Çocuklar İçin Zeka ölçeği kullanılmıştır. Bulgular: Çalışmamızda düşük ebeveyn eğitim düzeyi, ebeveyn işsizliği, düşük gelirli aile ve birinci derece akrabalarda psikiyatrik hastalık öyküsü ÖÖB riski ile, prematürite öyküsü ve erken dönem kendini düzenleme güçlükleri OSB riski ile, allerji öyküsü DEHB riski ile ilişkili bulunmuştur. Sonuç: Bu çalışmada nörogelişimsel bozukluklarda olası rol oynayan pek çok farklı risk faktörü bulunması ileri epigenetik çalışmalara ihtiyaç olduğunu göstermektedir.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Şahin B, Bozkurt a, Karabekiroglu K (2019). Perinatal and Medical Risk Factors in Children with Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder or Specific Learning Disorder: Comparison Between Diagnostic Groups. , 502 - 507. 10.4274/imj.galenos.2019.02347 |
| Chicago | Şahin Berkan,Bozkurt abdullah,Karabekiroglu Koray Perinatal and Medical Risk Factors in Children with Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder or Specific Learning Disorder: Comparison Between Diagnostic Groups. (2019): 502 - 507. 10.4274/imj.galenos.2019.02347 |
| MLA | Şahin Berkan,Bozkurt abdullah,Karabekiroglu Koray Perinatal and Medical Risk Factors in Children with Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder or Specific Learning Disorder: Comparison Between Diagnostic Groups. , 2019, ss.502 - 507. 10.4274/imj.galenos.2019.02347 |
| AMA | Şahin B,Bozkurt a,Karabekiroglu K Perinatal and Medical Risk Factors in Children with Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder or Specific Learning Disorder: Comparison Between Diagnostic Groups. . 2019; 502 - 507. 10.4274/imj.galenos.2019.02347 |
| Vancouver | Şahin B,Bozkurt a,Karabekiroglu K Perinatal and Medical Risk Factors in Children with Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder or Specific Learning Disorder: Comparison Between Diagnostic Groups. . 2019; 502 - 507. 10.4274/imj.galenos.2019.02347 |
| IEEE | Şahin B,Bozkurt a,Karabekiroglu K "Perinatal and Medical Risk Factors in Children with Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder or Specific Learning Disorder: Comparison Between Diagnostic Groups." , ss.502 - 507, 2019. 10.4274/imj.galenos.2019.02347 |
| ISNAD | Şahin, Berkan vd. "Perinatal and Medical Risk Factors in Children with Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder or Specific Learning Disorder: Comparison Between Diagnostic Groups". (2019), 502-507. https://doi.org/10.4274/imj.galenos.2019.02347 |
| APA | Şahin B, Bozkurt a, Karabekiroglu K (2019). Perinatal and Medical Risk Factors in Children with Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder or Specific Learning Disorder: Comparison Between Diagnostic Groups. İstanbul Medical Journal, 20(6), 502 - 507. 10.4274/imj.galenos.2019.02347 |
| Chicago | Şahin Berkan,Bozkurt abdullah,Karabekiroglu Koray Perinatal and Medical Risk Factors in Children with Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder or Specific Learning Disorder: Comparison Between Diagnostic Groups. İstanbul Medical Journal 20, no.6 (2019): 502 - 507. 10.4274/imj.galenos.2019.02347 |
| MLA | Şahin Berkan,Bozkurt abdullah,Karabekiroglu Koray Perinatal and Medical Risk Factors in Children with Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder or Specific Learning Disorder: Comparison Between Diagnostic Groups. İstanbul Medical Journal, vol.20, no.6, 2019, ss.502 - 507. 10.4274/imj.galenos.2019.02347 |
| AMA | Şahin B,Bozkurt a,Karabekiroglu K Perinatal and Medical Risk Factors in Children with Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder or Specific Learning Disorder: Comparison Between Diagnostic Groups. İstanbul Medical Journal. 2019; 20(6): 502 - 507. 10.4274/imj.galenos.2019.02347 |
| Vancouver | Şahin B,Bozkurt a,Karabekiroglu K Perinatal and Medical Risk Factors in Children with Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder or Specific Learning Disorder: Comparison Between Diagnostic Groups. İstanbul Medical Journal. 2019; 20(6): 502 - 507. 10.4274/imj.galenos.2019.02347 |
| IEEE | Şahin B,Bozkurt a,Karabekiroglu K "Perinatal and Medical Risk Factors in Children with Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder or Specific Learning Disorder: Comparison Between Diagnostic Groups." İstanbul Medical Journal, 20, ss.502 - 507, 2019. 10.4274/imj.galenos.2019.02347 |
| ISNAD | Şahin, Berkan vd. "Perinatal and Medical Risk Factors in Children with Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder or Specific Learning Disorder: Comparison Between Diagnostic Groups". İstanbul Medical Journal 20/6 (2019), 502-507. https://doi.org/10.4274/imj.galenos.2019.02347 |
